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AGK elisa kit :: Human Acylglycerol Kinase ELISA Kit

Scan QR to view Datasheet Catalog #    MBS083508 AGK elisa kit
Unit / Price
48-Strip-Wells  /  $435 +1 FREE 8GB USB
96-Strip-Wells  /  $600 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,650 +3 FREE 8GB USB
10x96-Strip-Wells  /  $5,205 +6 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Acylglycerol Kinase (AGK), ELISA Kit

 Also Known As   

Human Acylglycerol Kinase ELISA Kit

 Product Gene Name   

AGK elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Request for Current Manual Insert    Request Current Manual
 OMIM    212350
 3D Structure    ModBase 3D Structure for Q53H12
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 Species Reactivity    Human
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 Preparation and Storage    Store all reagents at 2-8 degree C
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of AGK elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for AGK purchase    MBS083508 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Acylglycerol Kinase (AGK) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing AGK. The ELISA analytical biochemical technique of the MBS083508 kit is based on AGK antibody-AGK antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect AGK antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, AGK. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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NCBI/Uniprot data below describe general gene information for AGK. It may not necessarily be applicable to this product.
 NCBI GI #    8922701
 NCBI GeneID    55750
 NCBI Accession #    NP_060708.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_018238.3 [Other Products]
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 UniProt Primary Accession #    Q53H12 [Other Products]
 UniProt Secondary Accession #    Q75KN1; Q96GC3; Q9NP48 [Other Products]
 UniProt Related Accession #    Q53H12 [Other Products]
 Molecular Weight    47,137 Da
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 NCBI Official Full Name    acylglycerol kinase, mitochondrial
 NCBI Official Synonym Full Names    acylglycerol kinase
 NCBI Official Symbol    AGK [Similar Products]
 NCBI Official Synonym Symbols   
MULK; CATC5; CTRCT38; MTDPS10
[Similar Products]
 NCBI Protein Information    acylglycerol kinase, mitochondrial; hAGK; hsMuLK; multi-substrate lipid kinase; multiple substrate lipid kinase
 UniProt Protein Name    Acylglycerol kinase, mitochondrial
 UniProt Synonym Protein Names   
Multiple substrate lipid kinase
 Protein Family    Acylglycerol kinase
 UniProt Gene Name    AGK [Similar Products]
 UniProt Synonym Gene Names    MULK; hAGK; HsMuLK; MuLK [Similar Products]
 UniProt Entry Name    AGK_HUMAN
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 NCBI Summary for AGK    The protein encoded by this gene is a mitochondrial membrane protein involved in lipid and glycerolipid metabolism. The encoded protein is a lipid kinase that catalyzes the formation of phosphatidic and lysophosphatidic acids. Defects in this gene have been associated with mitochondrial DNA depletion syndrome 10. [provided by RefSeq, Feb 2012]
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 UniProt Comments for AGK    AGK: Lipid kinase that can phosphorylate both monoacylglycerol and diacylglycerol to form lysophosphatidic acid (LPA) and phosphatidic acid (PA), respectively. Does not phosphorylate sphingosine. Overexpression increases the formation and secretion of LPA, resulting in transactivation of EGFR and activation of the downstream MAPK signaling pathway, leading to increased cell growth. Defects in AGK are the cause of mitochondrial DNA depletion syndrome type 10 (MTDPS10). An autosomal recessive mitochondrial disorder characterized by congenital cataracts, hypertrophic cardiomyopathy, skeletal myopathy, exercise intolerance, and lactic acidosis. Mental development is normal, but affected individuals may die early from cardiomyopathy. Defects in AGK are the cause of cataract, congenital, autosomal recessive type 5 (CATC5). CATC5 consists of an opacification of the crystalline lens of the eye becoming evident at birth. It frequently results in visual impairment or blindness. Opacities vary in morphology, are often confined to a portion of the lens, and may be static or progressive. In general, the more posteriorly located and dense an opacity, the greater the impact on visual function. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Kinase, lipid; EC 2.7.1.107; Lipid Metabolism - glycerolipid; Motility/polarity/chemotaxis; EC 2.7.1.94

Chromosomal Location of Human Ortholog: 7q34

Cellular Component: intracellular membrane-bound organelle; mitochondrion; mitochondrial membrane

Molecular Function: acylglycerol kinase activity; ceramide kinase activity; diacylglycerol kinase activity; ATP binding; NAD+ kinase activity

Biological Process: protein kinase C activation; glycerolipid metabolic process; ceramide biosynthetic process; lipid phosphorylation

Disease: Cataract 38; Sengers Syndrome
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 Research Articles on AGK    1. Our findings suggest that ATX-AGK-LPA signaling axis might be an important player in the development and progression of diabetic retinopathy.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with AGK elisa kitDiseases associated with AGK elisa kit
 Products by Pathway  Pathway Diagram
 Glycerolipid Metabolism Pathway antibodies  Glycerolipid Metabolism Pathway Diagram
 Glycerolipid Metabolism Pathway antibodies  Glycerolipid Metabolism Pathway Diagram
 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >8 publications with AGK and Neoplasms
 Prostatic Diseases Antibodies  >4 publications with AGK and Prostatic Diseases
 Nervous System Diseases Antibodies  >3 publications with AGK and Nervous System Diseases
 Necrosis Antibodies  >2 publications with AGK and Necrosis
 Hyperplasia Antibodies  >1 publications with AGK and Hyperplasia
 Weight Gain Antibodies  >1 publications with AGK and Weight Gain
 Disease Models, Animal Antibodies  >1 publications with AGK and Disease Models, Animal
 Hypertrophy Antibodies  >1 publications with AGK and Hypertrophy
 Neoplasms, Experimental Antibodies  >1 publications with AGK and Neoplasms, Experimental
Organs/Tissues associated with AGK elisa kit
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >6 publications with AGK and Blood
 Skin Antibodies  >4 publications with AGK and Skin
 Lung Antibodies  >3 publications with AGK and Lung
 Muscle Antibodies  >3 publications with AGK and Muscle
 Vascular Antibodies  >3 publications with AGK and Vascular
 Brain Antibodies  >3 publications with AGK and Brain
 Thyroid Antibodies  >2 publications with AGK and Thyroid
 Eye Antibodies  >2 publications with AGK and Eye
 Cervix Antibodies  >2 publications with AGK and Cervix
 Uterus Antibodies  >1 publications with AGK and Uterus
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