NP_001123910.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
282,282 Da
NCBI Official Full Name
spectrin alpha chain, non-erythrocytic 1 isoform 1
NCBI Official Synonym Full Names
spectrin alpha, non-erythrocytic 1
NCBI Protein Information
spectrin alpha chain, non-erythrocytic 1
UniProt Protein Name
Spectrin alpha chain, non-erythrocytic 1
UniProt Synonym Protein Names
Alpha-II spectrin; Fodrin alpha chain; Spectrin, non-erythroid alpha subunit
UniProt Synonym Gene Names
NCBI Summary for SPTAN1
Spectrins are a family of filamentous cytoskeletal proteins that function as essential scaffold proteins that stabilize the plasma membrane and organize intracellular organelles. Spectrins are composed of alpha and beta dimers that associate to form tetramers linked in a head-to-head arrangement. This gene encodes an alpha spectrin that is specifically expressed in nonerythrocytic cells. The encoded protein has been implicated in other cellular functions including DNA repair and cell cycle regulation. Mutations in this gene are the cause of early infantile epileptic encephalopathy-5. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Sep 2010]
UniProt Comments for SPTAN1
Fodrin, which seems to be involved in secretion, interacts with calmodulin in a calcium-dependent manner and is thus candidate for the calcium-dependent movement of the cytoskeleton at the membrane.
Research Articles on SPTAN1
Precautions
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Products associated with SPTAN1 elisa kit
Pathways associated with SPTAN1 elisa kit
Diseases associated with SPTAN1 elisa kit
Organs/Tissues associated with SPTAN1 elisa kit
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