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AIMP1 elisa kit :: Human Aminoacyl tRNA Synthetase Complex Interacting Multifunctional Protein 1 (AIMP1) ELISA Kit

Scan QR to view Datasheet Catalog #    MBS2706980 (SPECIAL PROMOTIONAL PRICING for a limited time)
Typical Testing Data/Standard Curve (for reference only)
Unit / Price
24-Strip-Wells  /  $230 +1 FREE 8GB USB
48-Strip-Wells  /  $385 +1 FREE 8GB USB
96-Strip-Wells  /  $515 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,170 +2 FREE 8GB USB
10x96-Strip-Wells  /  $4,020 +5 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Aminoacyl tRNA Synthetase Complex Interacting Multifunctional Protein 1 (AIMP1), ELISA Kit

★Popular Item★
 Also Known As   

Human Aminoacyl tRNA Synthetase Complex Interacting Multifunctional Protein 1 (AIMP1) ELISA Kit

 Product Synonym Names    SCYE1; EMAP II; EMAP2; p43; Small Inducible Cytokine Subfamily E,Member 1; Endothelial monocyte-activating polypeptide II; Multisynthase complex auxiliary component p43
 Product Gene Name   

AIMP1 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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  Sample Manual Insert    Download PDF Manual View PDF Manual
 Request for Current Manual Insert    Request Current Manual
 OMIM    U10117 mRNA
 3D Structure    ModBase 3D Structure for Q12904
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 Species Reactivity    Human
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 Specificity    This assay has high sensitivity and excellent specificity for detection of Aminoacyl tRNA Synthetase Complex Interacting Multifunctional Protein 1 (AIMP1).
No significant cross-reactivity or interference between Aminoacyl tRNA Synthetase Complex Interacting Multifunctional Protein 1 (AIMP1) and analogues was observed.
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 Assay Type    Double-antibody Sandwich
 Samples    Serum, Plasma, Tissue Homogenates, Cell Lysates, Cell Culture Supernates and Other Biological Fluids
 Detection Range    125-8000pg/mL
 Sensitivity    < 44pg/mL
 Application    Enzyme-linked immunosorbent assay for Antigen Detection.
 Intra-assay Precision (Precision within an assay)    3 samples with low, middle and high level Aminoacyl tRNA Synthetase Complex Interacting Multifunctional Protein 1 (AIMP1) were tested 20 times on one plate, respectively.
 Inter-assay Precision (Precision between assays)    3 samples with low, middle and high level Aminoacyl tRNA Synthetase Complex Interacting Multifunctional Protein 1 (AIMP1) were tested on 3 different plates, 8 replicates in each plate.
 CV(%) =    SD/meanX100
 Intra-Assay    CV<10%
 Inter-Assay    CV<12%
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 Preparation and Storage    The stability of kit is determined by the loss rate of activity. The loss rate of this kit is less than 5% within the expiration date under appropriate storage condition.
To minimize extra influence on the performance, operation procedures and lab conditions, especially room temperature, air humidity, incubator temperature should be strictly controlled. It is also strongly suggested that the whole assay is performed by the same operator from the beginning to the end.
 ISO Certification    Manufactured in an ISO 9001:2008 and ISO 13485:2003 Certified Laboratory.
 Supply Chain Verification    Manufactured in a lab with traceable raw materials manufactured on site. Coordinated product portfolio of antibodies, pairs, conjugates, recombinant proteins, and immunoassay materials available. Please inquire.
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of AIMP1 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for AIMP1 purchase    MBS2706980 is a ready-to-use microwell, strip plate Double-antibody Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Aminoacyl tRNA Synthetase Complex Interacting Multifunctional Protein 1 (AIMP1) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range of 125-8000pg/mL in biological research samples containing AIMP1, with an estimated sensitivity of < 44pg/mL. The ELISA analytical biochemical technique of the MBS2706980 kit is based on AIMP1 antibody-AIMP1 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect AIMP1 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, AIMP1. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions such as Serum, Plasma, Tissue Homogenates, Cell Lysates, Cell Culture Supernates and Other Biological Fluids. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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Related Product Information for AIMP1 elisa kit

   The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Aminoacyl tRNA Synthetase Complex Interacting Multifunctional Protein 1 (AIMP1). Standards or samples are then added to the appropriate microtiter plate wells with a biotin-conjugated antibody specific to Aminoacyl tRNA Synthetase Complex Interacting Multifunctional Protein 1 (AIMP1). Next, Avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. After TMB substrate solution is added, only those wells that contain Aminoacyl tRNA Synthetase Complex Interacting Multifunctional Protein 1 (AIMP1), biotin-conjugated antibody and enzyme-conjugated Avidin will exhibit a change in color. The enzyme-substrate reaction is terminated by the addition of sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450nm ± 10nm. The concentration of Aminoacyl tRNA Synthetase Complex Interacting Multifunctional Protein 1 (AIMP1) in the samples is then determined by comparing the O.D. of the samples to the standard curve.
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 Typical Testing Data/Standard Curve (for reference only) of AIMP1 elisa kit    AIMP1 elisa kit Typical Testing Data/Standard Curve (for reference only) image
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Sample Manual Insert of MBS2706980. Click to request current manual
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NCBI/Uniprot data below describe general gene information for AIMP1. It may not necessarily be applicable to this product.
 NCBI GI #    45006986
 NCBI GeneID    9255
 NCBI Accession #    NP_004748.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_004757.3 [Other Products]
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 UniProt Primary Accession #    Q12904 [Other Products]
 UniProt Secondary Accession #    Q6FG28; Q96CQ9; B3KTR2; B4E1S7 [Other Products]
 UniProt Related Accession #    Q12904 [Other Products]
 Molecular Weight    37,039 Da
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 NCBI Official Full Name    aminoacyl tRNA synthase complex-interacting multifunctional protein 1 isoform a
 NCBI Official Synonym Full Names    aminoacyl tRNA synthetase complex interacting multifunctional protein 1
 NCBI Official Symbol    AIMP1 [Similar Products]
 NCBI Official Synonym Symbols   
p43; HLD3; EMAP2; SCYE1; EMAPII
[Similar Products]
 NCBI Protein Information    aminoacyl tRNA synthase complex-interacting multifunctional protein 1
 UniProt Protein Name    Aminoacyl tRNA synthase complex-interacting multifunctional protein 1
 UniProt Synonym Protein Names   
Multisynthase complex auxiliary component p43
 Protein Family    Aminoacyl tRNA synthase complex-interacting multifunctional protein
 UniProt Gene Name    AIMP1 [Similar Products]
 UniProt Synonym Gene Names    EMAP2; SCYE1; EMAP-2; EMAP-II [Similar Products]
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 NCBI Summary for AIMP1    The protein encoded by this gene is a cytokine that is specifically induced by apoptosis, and it is involved in the control of angiogenesis, inflammation, and wound healing. The release of this cytokine renders the tumor-associated vasculature sensitive to tumor necrosis factor. The precursor protein is identical to the p43 subunit, which is associated with the multi-tRNA synthetase complex, and it modulates aminoacylation activity of tRNA synthetase in normal cells. This protein is also involved in the stimulation of inflammatory responses after proteolytic cleavage in tumor cells. Multiple transcript variants encoding different isoforms have been found for this gene. A pseudogene has been identified on chromosome 20. [provided by RefSeq, Dec 2008]
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 UniProt Comments for AIMP1    Non-catalytic component of the multisynthase complex. Stimulates the catalytic activity of cytoplasmic arginyl-tRNA synthase. Binds tRNA. Possesses inflammatory cytokine activity. Negatively regulates TGF-beta signaling through stabilization of SMURF2 by binding to SMURF2 and inhibiting its SMAD7-mediated degradation. Involved in glucose homeostasis through induction of glucagon secretion at low glucose levels. Promotes dermal fibroblast proliferation and wound repair. Regulates KDELR1-mediated retention of HSP90B1/gp96 in the endoplasmic reticulum. Plays a role in angiogenesis by inducing endothelial cell migration at low concentrations and endothelian cell apoptosis at high concentrations. Induces maturation of dendritic cells and monocyte cell adhesion. Modulates endothelial cell responses by degrading HIF-1A through interaction with PSMA7.
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 Research Articles on AIMP1    1. systemic mRNA expression of AIMP1 strongly differentiated children who failed to achieve asthma control with triamcinolone administration
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with AIMP1 elisa kitPathways associated with AIMP1 elisa kit
 Reference Product  PubMed Publications
 AIMP2 elisa kit  >6 publications with AIMP1 and AIMP2
 AIMP3 elisa kit  >3 publications with AIMP1 and AIMP3
 EPRS elisa kit  >2 publications with AIMP1 and EPRS
 RARS elisa kit  >2 publications with AIMP1 and RARS
 LARS elisa kit  >1 publications with AIMP1 and LARS
 DARS elisa kit  >1 publications with AIMP1 and DARS
 IARS elisa kit  >1 publications with AIMP1 and IARS
 KARS elisa kit  >1 publications with AIMP1 and KARS
 MARS elisa kit  >1 publications with AIMP1 and MARS
 Products by Pathway  Pathway Diagram
 Cytosolic TRNA Aminoacylation Pathway antibodies  Cytosolic TRNA Aminoacylation Pathway Diagram
 Gene Expression Pathway antibodies  Gene Expression Pathway Diagram
 TRNA Aminoacylation Pathway antibodies  TRNA Aminoacylation Pathway Diagram
Diseases associated with AIMP1 elisa kitOrgans/Tissues associated with AIMP1 elisa kit
 Disease Name  Pubmed Publications
 Inflammation Antibodies  >7 publications with AIMP1 and Inflammation
 Lung Diseases Antibodies  >4 publications with AIMP1 and Lung Diseases
 Cardiovascular Diseases Antibodies  >1 publications with AIMP1 and Cardiovascular Diseases
 Nervous System Malformations Antibodies  >1 publications with AIMP1 and Nervous System Malformations
 Breast Neoplasms Antibodies  >1 publications with AIMP1 and Breast Neoplasms
 Fibrosis Antibodies  >1 publications with AIMP1 and Fibrosis
 Congenital Abnormalities Antibodies  >1 publications with AIMP1 and Congenital Abnormalities
 Liver Diseases Antibodies  >1 publications with AIMP1 and Liver Diseases
 Hyperplasia Antibodies  >1 publications with AIMP1 and Hyperplasia
 Necrosis Antibodies  >1 publications with AIMP1 and Necrosis
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >12 publications with AIMP1 and Blood
 Stomach Antibodies  >3 publications with AIMP1 and Stomach
 Lung Antibodies  >3 publications with AIMP1 and Lung
 Vascular Antibodies  >3 publications with AIMP1 and Vascular
 Bone Antibodies  >3 publications with AIMP1 and Bone
 Muscle Antibodies  >2 publications with AIMP1 and Muscle
 Intestine Antibodies  >2 publications with AIMP1 and Intestine
 Spleen Antibodies  >2 publications with AIMP1 and Spleen
 Brain Antibodies  >2 publications with AIMP1 and Brain
 Liver Antibodies  >1 publications with AIMP1 and Liver
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