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ADG elisa kit :: Human Androgen ELISA Kit

Scan QR to view Datasheet Catalog #    MBS027449
Typical Testing Data/Standard Curve (for reference only)
Unit / Price
48-Strip-Wells  /  $435 +1 FREE 8GB USB
96-Strip-Wells  /  $600 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,650 +3 FREE 8GB USB
10x96-Strip-Wells  /  $5,205 +6 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Androgen (ADG), ELISA Kit

 Also Known As   

Human Androgen ELISA Kit

 Product Gene Name   

ADG elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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  Sample Manual Insert    Download PDF Manual View PDF Manual
 Request for Current Manual Insert    Request Current Manual
 OMIM    300068
 3D Structure    ModBase 3D Structure for P10275
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 Species Reactivity    Human
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 Specificity    No significant cross-reactivity or interference between this analyte and analogues is observed.
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 Samples    Body fluids, tissue homogenates, secretions or feces samples
 Assay Type    Quantitative Sandwich
 Detection Range    0.625 ng/ml - 20 ng/ml
 Sensitivity    0.1 ng/ml.
 Intra-assay Precision    Intra-assay CV (%) is less than 15%
 Inter-assay Precision    Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean 100].
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 Preparation and Storage    Store all reagents at 2-8 degree C
 Product Note    Our ELISA assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of ADG elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for ADG purchase    MBS027449 is a ready-to-use microwell, strip plate Quantitative Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Androgen (ADG) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range of 0.625 ng/ml - 20 ng/ml in biological research samples containing ADG, with an estimated sensitivity of 0.1 ng/ml. The ELISA analytical biochemical technique of the MBS027449 kit is based on ADG antibody-ADG antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect ADG antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, ADG. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions such as Body fluids, tissue homogenates, secretions or feces samples. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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Product Description specifically for ADG elisa kit

   Background/Introduction: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of ADG (hereafter termed "analyte") in undiluted original Human body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.
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 Typical Testing Data/Standard Curve (for reference only) of ADG elisa kit    ADG elisa kit Typical Testing Data/Standard Curve (for reference only) image
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Sample Manual Insert of MBS027449. Click to request current manual
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NCBI/Uniprot data below describe general gene information for ADG. It may not necessarily be applicable to this product.
 NCBI GI #    21322252
 NCBI GeneID    367
 NCBI Accession #    NP_000035.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_000044.3 [Other Products]
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 UniProt Primary Accession #    P10275 [Other Products]
 UniProt Secondary Accession #    Q9UD95; A2RUN2; B1AKD7 [Other Products]
 UniProt Related Accession #    P10275 [Other Products]
 Molecular Weight    98,989 Da
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 NCBI Official Full Name    androgen receptor isoform 1
 NCBI Official Synonym Full Names    androgen receptor
 NCBI Official Symbol    AR [Similar Products]
 NCBI Official Synonym Symbols   
KD; AIS; TFM; DHTR; SBMA; HYSP1; NR3C4; SMAX1; HUMARA
[Similar Products]
 NCBI Protein Information    androgen receptor; dihydrotestosterone receptor; androgen nuclear receptor variant 2; nuclear receptor subfamily 3 group C member 4
 UniProt Protein Name    Androgen receptor
 UniProt Synonym Protein Names   
Dihydrotestosterone receptor; Nuclear receptor subfamily 3 group C member 4
 Protein Family    Androgen receptor
 UniProt Gene Name    AR [Similar Products]
 UniProt Synonym Gene Names    DHTR; NR3C4 [Similar Products]
 UniProt Entry Name    ANDR_HUMAN
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 NCBI Summary for ADG    The androgen receptor gene is more than 90 kb long and codes for a protein that has 3 major functional domains: the N-terminal domain, DNA-binding domain, and androgen-binding domain. The protein functions as a steroid-hormone activated transcription factor. Upon binding the hormone ligand, the receptor dissociates from accessory proteins, translocates into the nucleus, dimerizes, and then stimulates transcription of androgen responsive genes. This gene contains 2 polymorphic trinucleotide repeat segments that encode polyglutamine and polyglycine tracts in the N-terminal transactivation domain of its protein. Expansion of the polyglutamine tract causes spinal bulbar muscular atrophy (Kennedy disease). Mutations in this gene are also associated with complete androgen insensitivity (CAIS). Two alternatively spliced variants encoding distinct isoforms have been described. [provided by RefSeq, Jul 2008]
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 UniProt Comments for ADG    AR: a nuclear hormone receptor and transcription factor. Regulates gene expression and affects cellular proliferation and differentiation in target tissues. Two splice-variant isoforms have been described.

Protein type: DNA-binding; Nuclear receptor; Transcription factor

Chromosomal Location of Human Ortholog: Xq12

Cellular Component: nucleoplasm; protein complex; nuclear chromatin; cytoplasm; nucleus

Molecular Function: protein dimerization activity; ligand-dependent nuclear receptor activity; androgen receptor activity; protein binding; enzyme binding; DNA binding; zinc ion binding; androgen binding; beta-catenin binding; chromatin binding; transcription factor activity; transcription factor binding; receptor binding

Biological Process: prostate gland development; transcription initiation from RNA polymerase II promoter; intracellular receptor-mediated signaling pathway; transcription, DNA-dependent; positive regulation of transcription, DNA-dependent; signal transduction; protein oligomerization; activation of NF-kappaB transcription factor; negative regulation of integrin biosynthetic process; cell proliferation; cell-cell signaling; transport; androgen receptor signaling pathway; positive regulation of cell proliferation; positive regulation of transcription from RNA polymerase III promoter; steroid hormone mediated signaling; gene expression; positive regulation of transcription from RNA polymerase II promoter; positive regulation of integrin biosynthetic process; cell growth; sex differentiation; positive regulation of phosphorylation

Disease: Androgen Insensitivity Syndrome; Prostate Cancer; Androgen Insensitivity, Partial; Hypospadias 1, X-linked; Spinal And Bulbar Muscular Atrophy, X-linked 1
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 Research Articles on ADG    1. Androgen-induced AR activating signal upregulates let-7a that targets CMYC and KRAS and contributes to ER-, PR-, AR+ breast cancer pathogenesis.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with ADG elisa kitPathways associated with ADG elisa kit
 Reference Product  PubMed Publications
 SRC elisa kit  >655 publications with ADG and SRC
 CTNNB1 elisa kit  >648 publications with ADG and CTNNB1
 NCOA1 elisa kit  >62 publications with ADG and NCOA1
 NCOA4 elisa kit  >55 publications with ADG and NCOA4
 NCOA2 elisa kit  >50 publications with ADG and NCOA2
 UBC elisa kit  >40 publications with ADG and UBC
 NCOR1 elisa kit  >27 publications with ADG and NCOR1
 NCOR2 elisa kit  >26 publications with ADG and NCOR2
 KLK3 elisa kit  >25 publications with ADG and KLK3
 NCOA3 elisa kit  >24 publications with ADG and NCOA3
 Products by Pathway  Pathway Diagram
 Alpha6-Beta4 Integrin Signaling Pathway antibodies  Alpha6-Beta4 Integrin Signaling Pathway Diagram
 Androgen Receptor Signaling Pathway antibodies  Androgen Receptor Signaling Pathway Diagram
 Coregulation Of Androgen Receptor Activity Pathway antibodies  Coregulation Of Androgen Receptor Activity Pathway Diagram
 FOXA1 Transcription Factor Network Pathway antibodies  FOXA1 Transcription Factor Network Pathway Diagram
 Gene Expression Pathway antibodies  Gene Expression Pathway Diagram
 Generic Transcription Pathway antibodies  Generic Transcription Pathway Diagram
 IL-6 Signaling Pathway antibodies  IL-6 Signaling Pathway Diagram
 Integrated Breast Cancer Pathway antibodies  Integrated Breast Cancer Pathway Diagram
 Integrated Pancreatic Cancer Pathway antibodies  Integrated Pancreatic Cancer Pathway Diagram
 Nongenotropic Androgen Signaling Pathway antibodies  Nongenotropic Androgen Signaling Pathway Diagram
Diseases associated with ADG elisa kitOrgans/Tissues associated with ADG elisa kit
 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >10558 publications with ADG and Neoplasms
 Inflammation Antibodies  >5108 publications with ADG and Inflammation
 Heart Diseases Antibodies  >4070 publications with ADG and Heart Diseases
 Genital Diseases, Male Antibodies  >3701 publications with ADG and Genital Diseases, Male
 Necrosis Antibodies  >3261 publications with ADG and Necrosis
 Prostatic Neoplasms Antibodies  >2905 publications with ADG and Prostatic Neoplasms
 Kidney Diseases Antibodies  >1909 publications with ADG and Kidney Diseases
 Hypertension Antibodies  >1401 publications with ADG and Hypertension
 Breast Neoplasms Antibodies  >1262 publications with ADG and Breast Neoplasms
 Liver Diseases Antibodies  >1250 publications with ADG and Liver Diseases
 Organ/Tissue Name  Pubmed Publications
 Bone Antibodies  >16196 publications with ADG and Bone
 Muscle Antibodies  >12740 publications with ADG and Muscle
 Skin Antibodies  >8867 publications with ADG and Skin
 Heart Antibodies  >6479 publications with ADG and Heart
 Vascular Antibodies  >5454 publications with ADG and Vascular
 Brain Antibodies  >5031 publications with ADG and Brain
 Prostate Antibodies  >4425 publications with ADG and Prostate
 Kidney Antibodies  >3613 publications with ADG and Kidney
 Liver Antibodies  >3192 publications with ADG and Liver
 Lung Antibodies  >2470 publications with ADG and Lung
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