View our list of available Coronavirus (COVID-19, SARS-CoV-2, 2019-nCOV) antibodies, recombinant proteins, ELISA Kits... Options Full Datasheet Printer Friendly Datasheet Prepare for Printing Full Datasheet Printer Friendly Datasheet Prepare for Printing Have Questions? Ask Us! Add To Compare List ACE elisa kit :: Human Angiotensin Converting Enzyme ELISA Kit Catalog # MBS7253919 Unit / Price DISCONTINUEDYou will be redirected to our replacement product Product Name Product Info Accession #s Product Desc Diseases/Tissues/Pathways Applications References Product Name Angiotensin Converting Enzyme (ACE), ELISA Kit Full Product Name Human Angiotensin Converting Enzyme ELISA Kit Product Gene Name ACE elisa kit[Similar Products] Research Use Only For Research Use Only. Not for use in diagnostic procedures. TOP Sample Manual Insert Download Sample PDF Manual View Sample PDF Manual OMIM J04144 mRNA Species Reactivity Human Specificity This assay has high sensitivity and excellent specificity for detection of ACE. No significant cross-reactivity or interference between ACE and analogues was observed. NOTE: Limited by current skills and knowledge, it is impossible for us to complete the cross-reactivity detection between ACE and all the analogues, therefore, cross reaction may still exist in some cases. Samples Serum, plasma, cell culture supernatants, body fluid and tissue homogenate Assay Type Quantitative Competitive Sensitivity 1.0 pg/mL Sample Preparation We suggest pre-experimenting with neat (undiluted) samples, 1:2 or 1:4 dilutions. Please avoid diluting your samples more than 1:10 as it would exceed the dilution limit set for this kit. If the expected concentration of the target is beyond the detection range of the kit, please contact our technical support team ISO Certification Manufactured in an ISO 13485:2016 Certified Laboratory. Product Note Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details. Other Notes Small volumes of ACE elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply. Searchable Terms for ACE purchase MBS7253919 is a ready-to-use microwell, strip-or-full plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Angiotensin Converting Enzyme (ACE) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing ACE. The ELISA analytical biochemical technique of the MBS7253919 kit is based on ACE antibody-ACE antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect ACE antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, ACE. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%). TOP Related Product Information for ACE elisa kit Intended Uses: This ACE ELISA kit is a 1.5 hour solid-phase ELISA designed for the quantitative determination of Human ACE. This ELISA kit for research use only!Principle of the Assay: ACE ELISA kit applies the competitive enzyme immunoassay technique utilizing an anti-ACE antibody and an ACE-HRP conjugate. The assay sample and buffer are incubated together with ACE-HRP conjugate in pre-coated plate for one hour. After the incubation period, the wells are decanted and washed five times. The wells are then incubated with a substrate for HRP enzyme. The product of the enzyme-substrate reaction forms a blue colored complex. Finally, a stop solution is added to stop the reaction, which will then turn the solution yellow. The intensity of color is measured spectrophotometrically at 450nm in a microplate reader. The intensity of the color is inversely proportional to the ACE concentration since ACE from samples and ACE-HRP conjugate compete for the anti-ACE antibody binding site. Since the number of sites is limited, as more sites are occupied by ACE from the sample, fewer sites are left to bind ACE-HRP conjugate. A standard curve is plotted relating the intensity of the color (O.D.) to the concentration of standards. The ACE concentration in each sample is interpolated from this standard curve. Typical Testing Data/Standard Curve (for reference only) of ACE elisa kit TOP Sample Manual Insert of MBS7253919. NCBI/Uniprot data below describe general gene information for ACE. It may not necessarily be applicable to this product. NCBI GI # 338667 NCBI GeneID 1636 NCBI Accession # AAA60611.1 [Other Products] UniProt Secondary Accession # P22966; Q53YX9; Q59GY8; Q7M4L4; B0LPF0; B4DXI3; E7EU16[Other Products] UniProt Related Accession # P12821[Other Products] Molecular Weight 78,694 Da TOP NCBI Official Full Name angiotensin converting enzyme (EC 3.4.15.1) NCBI Official Synonym Full Names angiotensin I converting enzyme NCBI Official Symbol ACE [Similar Products] NCBI Official Synonym Symbols DCP; ACE1; DCP1; CD143 [Similar Products] NCBI Protein Information angiotensin-converting enzyme UniProt Protein Name Angiotensin-converting enzyme UniProt Synonym Protein Names Dipeptidyl carboxypeptidase I; Kininase II; CD_antigen: CD143 Protein Family Acetylcholinesterase UniProt Gene Name ACE [Similar Products] UniProt Synonym Gene Names DCP; DCP1; ACE [Similar Products] TOP NCBI Summary for ACE This gene encodes an enzyme involved in catalyzing the conversion of angiotensin I into a physiologically active peptide angiotensin II. Angiotensin II is a potent vasopressor and aldosterone-stimulating peptide that controls blood pressure and fluid-electrolyte balance. This enzyme plays a key role in the renin-angiotensin system. Many studies have associated the presence or absence of a 287 bp Alu repeat element in this gene with the levels of circulating enzyme or cardiovascular pathophysiologies. Multiple alternatively spliced transcript variants encoding different isoforms have been identified, and two most abundant spliced variants encode the somatic form and the testicular form, respectively, that are equally active. [provided by RefSeq, May 2010] TOP UniProt Comments for ACE Converts angiotensin I to angiotensin II by release of the terminal His-Leu, this results in an increase of the vasoconstrictor activity of angiotensin. Also able to inactivate bradykinin, a potent vasodilator. Has also a glycosidase activity which releases GPI-anchored proteins from the membrane by cleaving the mannose linkage in the GPI moiety. Research Articles on ACE 1. The current meta-analysis provided solid evidence suggesting that ACE gene I/D polymorphism was probably a genetic risk factor for HCM. TOP Precautions All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines. Disclaimer While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information. TOP Products associated with ACE elisa kit Reference Product PubMed Publications AGT elisa kit >554 publications with ACE and AGT AGTR2 elisa kit >418 publications with ACE and AGTR2 REN elisa kit >192 publications with ACE and REN NOS3 elisa kit >189 publications with ACE and NOS3 AGTR1 elisa kit >186 publications with ACE and AGTR1 CRP elisa kit >140 publications with ACE and CRP INS elisa kit >63 publications with ACE and INS SERPINE1 elisa kit >41 publications with ACE and SERPINE1 TFPI elisa kit >12 publications with ACE and TFPI KNG1 elisa kit >3 publications with ACE and KNG1 Pathways associated with ACE elisa kit Products by Pathway Pathway Diagram ACE Inhibitor Pathway antibodies ACE Inhibitor Pathway Diagram Chagas Disease (American Trypanosomiasis) Pathway antibodies Chagas Disease (American Trypanosomiasis) Pathway Diagram Chagas Disease (American Trypanosomiasis) Pathway antibodies Chagas Disease (American Trypanosomiasis) Pathway Diagram Hypertrophic Cardiomyopathy (HCM) Pathway antibodies Hypertrophic Cardiomyopathy (HCM) Pathway Diagram Hypertrophic Cardiomyopathy (HCM) Pathway antibodies Hypertrophic Cardiomyopathy (HCM) Pathway Diagram Metabolism Of Angiotensinogen To Angiotensins Pathway antibodies Metabolism Of Angiotensinogen To Angiotensins Pathway Diagram Metabolism Of Proteins Pathway antibodies Metabolism Of Proteins Pathway Diagram Peptide Hormone Metabolism Pathway antibodies Peptide Hormone Metabolism Pathway Diagram Renin Secretion Pathway antibodies Renin Secretion Pathway Diagram Renin Secretion Pathway antibodies Renin Secretion Pathway Diagram Diseases associated with ACE elisa kit Disease Name Pubmed Publications Cardiovascular Diseases Antibodies >15046 publications with ACE and Cardiovascular Diseases Hypertension Antibodies >9803 publications with ACE and Hypertension Heart Failure Antibodies >5038 publications with ACE and Heart Failure Kidney Diseases Antibodies >3808 publications with ACE and Kidney Diseases Myocardial Infarction Antibodies >2747 publications with ACE and Myocardial Infarction Coronary Disease Antibodies >2397 publications with ACE and Coronary Disease Stroke Antibodies >1618 publications with ACE and Stroke Renal Insufficiency Antibodies >1499 publications with ACE and Renal Insufficiency Respiratory Tract Diseases Antibodies >1453 publications with ACE and Respiratory Tract Diseases Coronary Artery Disease Antibodies >1377 publications with ACE and Coronary Artery Disease Organs/Tissues associated with ACE elisa kit Organ/Tissue Name Pubmed Publications Blood Antibodies >13418 publications with ACE and Blood Heart Antibodies >9103 publications with ACE and Heart Vascular Antibodies >4987 publications with ACE and Vascular Kidney Antibodies >4689 publications with ACE and Kidney Muscle Antibodies >2349 publications with ACE and Muscle Lung Antibodies >1737 publications with ACE and Lung Brain Antibodies >1560 publications with ACE and Brain Intestine Antibodies >334 publications with ACE and Intestine Eye Antibodies >288 publications with ACE and Eye Testis Antibodies >236 publications with ACE and Testis TOP © 2006-24 MyBioSource.com. 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