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ASA elisa kit :: Human Anti-Skin Antibody (ASA) ELISA Kit

Scan QR to view Datasheet Catalog #    MBS260713 ASA elisa kit
Unit / Price
48-Strip-Wells  /  $275 +1 FREE 8GB USB
96-Strip-Wells  /  $420 +1 FREE 8GB USB
5x96-Strip-Wells  /  $1,615 +2 FREE 8GB USB
10x96-Strip-Wells  /  $2,880 +3 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Anti-Skin Antibody (ASA), ELISA Kit

 Also Known As   

Human Anti-Skin Antibody (ASA) ELISA Kit

 Product Gene Name   

ASA elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Request for Current Manual Insert    Request Current Manual
 OMIM    600040
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 Species Reactivity    Human
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 Preparation and Storage    Store all reagents at 2-8 degree C.
 Product Note    Our ELISA assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of ASA elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for ASA purchase    MBS260713 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Anti-Skin Antibody (ASA) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing ASA. The ELISA analytical biochemical technique of the MBS260713 kit is based on ASA antibody-ASA antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect ASA antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, ASA. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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NCBI/Uniprot data below describe general gene information for ASA. It may not necessarily be applicable to this product.
 NCBI GI #    728945
 NCBI GeneID    581
 NCBI Accession #    Q07812.1 [Other Products]
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 UniProt Secondary Accession #    P55269; Q07814; Q07815; Q8WZ49; Q9NR76; Q9NYG7; Q9UCZ6; Q9UCZ7; Q9UQD6; A8K4W1 [Other Products]
 UniProt Related Accession #    Q07812 [Other Products]
 Molecular Weight    19,718 Da
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 NCBI Official Full Name    Apoptosis regulator BAX
 NCBI Official Synonym Full Names    BCL2-associated X protein
 NCBI Official Symbol    BAX [Similar Products]
 NCBI Official Synonym Symbols   
BCL2L4
[Similar Products]
 NCBI Protein Information    apoptosis regulator BAX; bcl2-L-4; Baxdelta2G9; Baxdelta2omega; Baxdelta2G9omega; bcl-2-like protein 4; BCL2-associated X protein omega
 UniProt Protein Name    Apoptosis regulator BAX
 UniProt Synonym Protein Names   
Bcl-2-like protein 4; Bcl2-L-4
 UniProt Gene Name    BAX [Similar Products]
 UniProt Synonym Gene Names    BCL2L4; Bcl2-L-4 [Similar Products]
 UniProt Entry Name    BAX_HUMAN
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 NCBI Summary for ASA    The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein forms a heterodimer with BCL2, and functions as an apoptotic activator. This protein is reported to interact with, and increase the opening of, the mitochondrial voltage-dependent anion channel (VDAC), which leads to the loss in membrane potential and the release of cytochrome c. The expression of this gene is regulated by the tumor suppressor P53 and has been shown to be involved in P53-mediated apoptosis. Multiple alternatively spliced transcript variants, which encode different isoforms, have been reported for this gene. [provided by RefSeq, Jul 2008]
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 UniProt Comments for ASA    BAX: Accelerates programmed cell death by binding to, and antagonizing the apoptosis repressor BCL2 or its adenovirus homolog E1B 19k protein. Under stress conditions, undergoes a conformation change that causes translocation to the mitochondrion membrane, leading to the release of cytochrome c that then triggers apoptosis. Promotes activation of CASP3, and thereby apoptosis. Homodimer. Forms higher oligomers under stress conditions. Interacts with BCL2L11. Interaction with BCL2L11 promotes BAX oligomerization and association with mitochondrial membranes, with subsequent release of cytochrome c. Forms heterodimers with BCL2, E1B 19K protein, BCL2L1 isoform Bcl-X(L), BCL2L2, MCL1 and A1. Interacts with SH3GLB1 and HN. Interacts with SFN and YWHAZ; the interaction occurs in the cytoplasm. Under stress conditions, JNK-mediated phosphorylation of SFN and YWHAZ, releases BAX to mitochondria. Isoform Sigma interacts with BCL2A1 and BCL2L1 isoform Bcl-X(L). Interacts with RNF144B, which regulates the ubiquitin-dependent stability of BAX. Interacts with CLU under stress conditions that cause a conformation change leading to BAX oligomerization and association with mitochondria. Does not interact with CLU in unstressed cells. Interacts with FAIM2/LFG2. Interacts with human cytomegalovirus/HHV-5 protein vMIA/UL37. Expressed in a wide variety of tissues. Isoform Psi is found in glial tumors. Isoform Alpha is expressed in spleen, breast, ovary, testis, colon and brain, and at low levels in skin and lung. Isoform Sigma is expressed in spleen, breast, ovary, testis, lung, colon, brain and at low levels in skin. Isoform Alpha and isoform Sigma are expressed in pro- myelocytic leukemia, histiocytic lymphoma, Burkitt's lymphoma, T- cell lymphoma, lymphoblastic leukemia, breast adenocarcinoma, ovary adenocarcinoma, prostate carcinoma, prostate adenocarcinoma, lung carcinoma, epidermoid carcinoma, small cell lung carcinoma and colon adenocarcinoma cell lines. Belongs to the Bcl-2 family. 8 isoforms of the human protein are produced by alternative splicing.

Protein type: Apoptosis; Tumor suppressor; Mitochondrial; Membrane protein, integral

Chromosomal Location of Human Ortholog: 19q13.3-q13.4

Cellular Component: mitochondrial permeability transition pore complex; pore complex; mitochondrial outer membrane; endoplasmic reticulum membrane; membrane; mitochondrion; endoplasmic reticulum; nuclear envelope; nucleus; cytosol

Molecular Function: identical protein binding; protein binding; protein homodimerization activity; protein heterodimerization activity; channel activity; BH3 domain binding; lipid binding

Biological Process: hypothalamus development; viral reproduction; regulation of cell cycle; positive regulation of apoptosis; response to toxin; germ cell programmed cell death; myeloid cell homeostasis; B cell apoptosis; germ cell development; regulation of mammary gland epithelial cell proliferation; spermatid differentiation; regulation of mitochondrial membrane potential; development of secondary sexual characteristics; protein insertion into mitochondrial membrane during induction of apoptosis; establishment and/or maintenance of transmembrane electrochemical gradient; negative regulation of neuron apoptosis; kidney development; negative regulation of protein binding; release of cytochrome c from mitochondria; positive regulation of B cell apoptosis; regulation of protein homodimerization activity; vagina development; protein oligomerization; unfolded protein response, activation of signaling protein activity; fertilization; DNA damage response, signal transduction resulting in induction of apoptosis; induction of apoptosis via death domain receptors; retina development in camera-type eye; negative regulation of fibroblast proliferation; reduction of endoplasmic reticulum calcium ion concentration; glycosphingolipid metabolic process; cerebral cortex development; mitochondrial fragmentation during apoptosis; regulation of nitrogen utilization; post-embryonic camera-type eye morphogenesis; regulation of protein heterodimerization activity; positive regulation of pigmentation; T cell homeostatic proliferation; apoptosis; neuron migration; positive regulation of apoptosis involved in mammary gland involution; negative regulation of peptidyl-serine phosphorylation; response to salt stress; release of matrix enzymes from mitochondria; positive regulation of protein oligomerization; apoptotic mitochondrial changes; B cell homeostatic proliferation; ovarian follicle development; B cell homeostasis; positive regulation of neuron apoptosis; response to gamma radiation; response to axon injury; B cell negative selection; protein homooligomerization; caspase activation; transformed cell apoptosis; mitochondrial fusion; Sertoli cell proliferation; odontogenesis of dentine-containing teeth; neuron apoptosis; endoplasmic reticulum calcium ion homeostasis; homeostasis of number of cells within a tissue; blood vessel remodeling; retinal cell programmed cell death; caspase activation via cytochrome c; positive regulation of release of sequestered calcium ion into cytosol
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 Research Articles on ASA    1. miR-511 regulates the growth of radioresistant lung cancer cells by increasing BAX expression through TRIB2.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with ASA elisa kitDiseases associated with ASA elisa kit
 Products by Pathway  Pathway Diagram
 Activation, Translocation And Oligomerization Of BAX Pathway antibodies  Activation, Translocation And Oligomerization Of BAX Pathway Diagram
 AhR Pathway antibodies  AhR Pathway Diagram
 Amyotrophic Lateral Sclerosis (ALS) Pathway antibodies  Amyotrophic Lateral Sclerosis (ALS) Pathway Diagram
 Amyotrophic Lateral Sclerosis (ALS) Pathway antibodies  Amyotrophic Lateral Sclerosis (ALS) Pathway Diagram
 Amyotrophic Lateral Sclerosis (ALS) Pathway antibodies  Amyotrophic Lateral Sclerosis (ALS) Pathway Diagram
 Apoptosis Pathway antibodies  Apoptosis Pathway Diagram
 Apoptosis Pathway antibodies  Apoptosis Pathway Diagram
 Apoptosis Pathway antibodies  Apoptosis Pathway Diagram
 Apoptosis Pathway antibodies  Apoptosis Pathway Diagram
 Apoptosis Modulation And Signaling Pathway antibodies  Apoptosis Modulation And Signaling Pathway Diagram
 Disease Name  Pubmed Publications
 Necrosis Antibodies  >1934 publications with ASA and Necrosis
 Heart Diseases Antibodies  >1800 publications with ASA and Heart Diseases
 Nervous System Diseases Antibodies  >1790 publications with ASA and Nervous System Diseases
 Ischemia Antibodies  >1458 publications with ASA and Ischemia
 Brain Diseases Antibodies  >1334 publications with ASA and Brain Diseases
 Inflammation Antibodies  >966 publications with ASA and Inflammation
 Breast Neoplasms Antibodies  >923 publications with ASA and Breast Neoplasms
 Liver Diseases Antibodies  >919 publications with ASA and Liver Diseases
 Intestinal Neoplasms Antibodies  >806 publications with ASA and Intestinal Neoplasms
 Neoplasms, Experimental Antibodies  >735 publications with ASA and Neoplasms, Experimental
Organs/Tissues associated with ASA elisa kit
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >3058 publications with ASA and Blood
 Brain Antibodies  >2320 publications with ASA and Brain
 Liver Antibodies  >1661 publications with ASA and Liver
 Lung Antibodies  >1263 publications with ASA and Lung
 Bone Antibodies  >759 publications with ASA and Bone
 Nerve Antibodies  >714 publications with ASA and Nerve
 Prostate Antibodies  >693 publications with ASA and Prostate
 Skin Antibodies  >502 publications with ASA and Skin
 Stomach Antibodies  >478 publications with ASA and Stomach
 Intestine Antibodies  >383 publications with ASA and Intestine
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