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APOL1 elisa kit :: Human Apolipoprotein L1 ELISA Kit

Scan QR to view Datasheet Catalog #    MBS021236 APOL1 elisa kit
Unit / Price
48-Strip-Wells  /  $470 +1 FREE 8GB USB
96-Strip-Wells  /  $680 +1 FREE 8GB USB
5x96-Strip-Wells  /  $3,100 +3 FREE 8GB USB
10x96-Strip-Wells  /  $6,095 +7 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Apolipoprotein L1 (APOL1), ELISA Kit

★Popular Item★
 Also Known As   

Human Apolipoprotein L1 ELISA Kit

 Product Gene Name   

APOL1 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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  Sample Manual Insert    Download PDF Manual View PDF Manual
 Request for Current Manual Insert    Request Current Manual
 Chromosome Location    Chromosome: 22; NC_000022.10 (36649117..36663577). Location: 22q13.1
 OMIM    603743
 3D Structure    ModBase 3D Structure for O14791
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 Species Reactivity    Human
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 Specificity    No significant cross-reactivity or interference between this analyte and analogues is observed.
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 Samples    Undiluted original Human body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.
 Assay Type    Sandwich
 Detection Range    0.25 umol/L - 8 umol/L.
 Sensitivity    0.1 umol/L.
 Intra-assay Precision    Intra-assay CV (%) is less than 15%.
 Inter-assay Precision    Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean 100].
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 Preparation and Storage    Store all reagents at 2-8 degree C
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of APOL1 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for APOL1 purchase    MBS021236 is a ready-to-use microwell, strip plate Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Apolipoprotein L1 (APOL1) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range of 0.25 umol/L - 8 umol/L in biological research samples containing APOL1, with an estimated sensitivity of 0.1 umol/L. The ELISA analytical biochemical technique of the MBS021236 kit is based on APOL1 antibody-APOL1 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect APOL1 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, APOL1. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions such as Undiluted original Human body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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Related Product Information for APOL1 elisa kit

   Background/Introduction: This Quantitative Sandwich ELISA kit is only for in vitro research use only, NOT for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of APOL1 (hereafter termed "analyte") in undiluted original Human body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.
Sample Manual Insert of MBS021236. Click to request current manual
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NCBI/Uniprot data below describe general gene information for APOL1. It may not necessarily be applicable to this product.
 NCBI GI #    211938442
 NCBI GeneID    8542
 NCBI Accession #    NP_001130013.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001136541.1 [Other Products]
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 UniProt Primary Accession #    O14791 [Other Products]
 UniProt Secondary Accession #    O60804; Q5R3P7; Q5R3P8; Q96AB8; Q96PM4; Q9BQ03; A5PLQ4; B4DU12; E9PF24 [Other Products]
 UniProt Related Accession #    O14791 [Other Products]
 Molecular Weight    43,974 Da
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 NCBI Official Full Name    apolipoprotein L1 isoform c
 NCBI Official Synonym Full Names    apolipoprotein L, 1
 NCBI Official Symbol    APOL1 [Similar Products]
 NCBI Official Synonym Symbols   
APOL; APO-L; FSGS4; APOL-I
[Similar Products]
 NCBI Protein Information    apolipoprotein L1
 UniProt Protein Name    Apolipoprotein L1
 UniProt Synonym Protein Names   
Apolipoprotein L; Apo-L; ApoL; Apolipoprotein L-I
 Protein Family    Apolipoprotein
 UniProt Gene Name    APOL1 [Similar Products]
 UniProt Synonym Gene Names    APOL; Apo-L; ApoL; ApoL-I [Similar Products]
 UniProt Entry Name    APOL1_HUMAN
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 NCBI Summary for APOL1    This gene encodes a secreted high density lipoprotein which binds to apolipoprotein A-I. Apolipoprotein A-I is a relatively abundant plasma protein and is the major apoprotein of HDL. It is involved in the formation of most cholesteryl esters in plasma and also promotes efflux of cholesterol from cells. This apolipoprotein L family member may play a role in lipid exchange and transport throughout the body, as well as in reverse cholesterol transport from peripheral cells to the liver. Several different transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2008]
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 UniProt Comments for APOL1    APOL1: May play a role in lipid exchange and transport throughout the body. May participate in reverse cholesterol transport from peripheral cells to the liver. Defects in APOL1 are the cause of focal segmental glomerulosclerosis type 4 (FSGS4). It is a renal pathology defined by the presence of segmental sclerosis in glomeruli and resulting in proteinuria, reduced glomerular filtration rate and edema. Renal insufficiency often progresses to end-stage renal disease, a highly morbid state requiring either dialysis therapy or kidney transplantation. Belongs to the apolipoprotein L family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Secreted, signal peptide; Lipid-binding; Channel, chloride; Secreted

Chromosomal Location of Human Ortholog: 22q13.1

Cellular Component: extracellular space; extracellular region; intrinsic to membrane

Molecular Function: protein binding; chloride channel activity; lipid binding

Biological Process: cholesterol metabolic process; receptor-mediated endocytosis; killing of cells of another organism; cytolysis; innate immune response; lipoprotein metabolic process; chloride transport; lipid transport

Disease: Focal Segmental Glomerulosclerosis 4, Susceptibility To
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 Research Articles on APOL1    1. APOL1 genotyping of African-American patients with systemic lupus erythematosus (SLE) might help identify patients at risk for collapsing glomerulopathy.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with APOL1 elisa kitPathways associated with APOL1 elisa kit
 Reference Product  PubMed Publications
 MYH9 elisa kit  >32 publications with APOL1 and MYH9
 HPR elisa kit  >14 publications with APOL1 and HPR
 APOA1 elisa kit  >3 publications with APOL1 and APOA1
 APOL3 elisa kit  >1 publications with APOL1 and APOL3
 APOL6 elisa kit  >1 publications with APOL1 and APOL6
 Products by Pathway  Pathway Diagram
 African Trypanosomiasis Pathway antibodies  African Trypanosomiasis Pathway Diagram
 African Trypanosomiasis Pathway antibodies  African Trypanosomiasis Pathway Diagram
 Binding And Uptake Of Ligands By Scavenger Receptors Pathway antibodies  Binding And Uptake Of Ligands By Scavenger Receptors Pathway Diagram
 Scavenging Of Heme From Plasma Pathway antibodies  Scavenging Of Heme From Plasma Pathway Diagram
Diseases associated with APOL1 elisa kitOrgans/Tissues associated with APOL1 elisa kit
 Disease Name  Pubmed Publications
 Kidney Diseases Antibodies  >61 publications with APOL1 and Kidney Diseases
 Renal Insufficiency Antibodies  >30 publications with APOL1 and Renal Insufficiency
 Glomerulosclerosis, Focal Segmental Antibodies  >29 publications with APOL1 and Glomerulosclerosis, Focal Segmental
 Hypertension Antibodies  >25 publications with APOL1 and Hypertension
 Immune System Diseases Antibodies  >18 publications with APOL1 and Immune System Diseases
 Proteinuria Antibodies  >16 publications with APOL1 and Proteinuria
 Schizophrenia Antibodies  >12 publications with APOL1 and Schizophrenia
 Atherosclerosis Antibodies  >6 publications with APOL1 and Atherosclerosis
 Inflammation Antibodies  >5 publications with APOL1 and Inflammation
 Necrosis Antibodies  >3 publications with APOL1 and Necrosis
 Organ/Tissue Name  Pubmed Publications
 Kidney Antibodies  >70 publications with APOL1 and Kidney
 Blood Antibodies  >47 publications with APOL1 and Blood
 Vascular Antibodies  >9 publications with APOL1 and Vascular
 Muscle Antibodies  >5 publications with APOL1 and Muscle
 Brain Antibodies  >4 publications with APOL1 and Brain
 Heart Antibodies  >3 publications with APOL1 and Heart
 Pancreas Antibodies  >2 publications with APOL1 and Pancreas
 Placenta Antibodies  >2 publications with APOL1 and Placenta
 Liver Antibodies  >2 publications with APOL1 and Liver
 Lung Antibodies  >2 publications with APOL1 and Lung
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