NP_004019.1
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NCBI GenBank Nucleotide #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
32,300 Da
NCBI Official Full Name
aquaporin-4 isoform b
NCBI Official Synonym Full Names
aquaporin 4
NCBI Official Synonym Symbols
NCBI Protein Information
aquaporin-4; WCH4; aquaporin type4; aquaporin 4 isoform delta4; mercurial-insensitive water channel
UniProt Protein Name
Aquaporin-4
UniProt Synonym Protein Names
Mercurial-insensitive water channel; MIWC; WCH4
UniProt Synonym Gene Names
UniProt Entry Name
AQP4_HUMAN
NCBI Summary for AQP 4
This gene encodes a member of the aquaporin family of intrinsic membrane proteins that function as water-selective channels in the plasma membranes of many cells. The encoded protein is the predominant aquaporin found in brain. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
UniProt Comments for AQP 4
AQP4: a member of the aquaporin family of intrinsic membrane proteins that function as water-selective channels in the plasma membranes of many cells. The predominant aquaporin found in brain. Two alternatively spliced transcript variants have been described
Protein type: Membrane protein, integral; Channel, misc.; Transporter; Membrane protein, multi-pass; Transporter, aquaporin family
Chromosomal Location of Human Ortholog: 18q11.2-q12.1
Cellular Component: protein complex; integral to plasma membrane; basolateral plasma membrane; T-tubule; cytoplasm; plasma membrane; intercellular junction; external side of plasma membrane
Molecular Function: water transporter activity; water channel activity; porin activity; glycerol channel activity
Biological Process: glycerol transport; cellular water homeostasis; carbon dioxide transport; water transport; response to glucocorticoid stimulus; female pregnancy; response to radiation; sensory perception of sound; hyperosmotic salinity response; transport; renal water homeostasis; multicellular organismal water homeostasis; transmembrane transport; protein homooligomerization
Research Articles on AQP 4
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Products associated with AQP 4 elisa kit
Pathways associated with AQP 4 elisa kit
Diseases associated with AQP 4 elisa kit
Organs/Tissues associated with AQP 4 elisa kit
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