NP_001032208.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
94,470 Da
NCBI Official Full Name
arf-GAP with GTPase, ANK repeat and PH domain-containing protein 1 isoform 1
NCBI Official Synonym Full Names
ArfGAP with GTPase domain, ankyrin repeat and PH domain 1
NCBI Protein Information
arf-GAP with GTPase, ANK repeat and PH domain-containing protein 1; centaurin, gamma 2; GTP-binding and GTPase-activating protein 1; Arf GAP with GTP-binding protein-like, ANK repeat and PH domains 1
UniProt Protein Name
Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 1
UniProt Synonym Protein Names
Centaurin-gamma-2; Cnt-g2; GTP-binding and GTPase-activating protein 1; GGAP1
UniProt Synonym Gene Names
UniProt Entry Name
AGAP1_HUMAN
NCBI Summary for AGAP1
This gene encodes a member of an ADP-ribosylation factor GTPase-activating protein family involved in membrane trafficking and cytoskeleton dynamics. This gene functions as a direct regulator of the adaptor-related protein complex 3 on endosomes. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]
UniProt Comments for AGAP1
CENTG2: GTPase-activating protein for ARF1 and, to a lesser extent, ARF5. Directly and specifically regulates the adapter protein 3 (AP-3)-dependent trafficking of proteins in the endosomal-lysosomal system. Belongs to the centaurin gamma-like family. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: GAPs, ARF; GAPs
Chromosomal Location of Human Ortholog: 2q37
Cellular Component: cytoplasm
Molecular Function: GTP binding; zinc ion binding; phospholipid binding
Biological Process: protein transport; small GTPase mediated signal transduction; positive regulation of GTPase activity
Research Articles on AGAP1
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Pathways associated with AGAP1 elisa kit
Diseases associated with AGAP1 elisa kit
Organs/Tissues associated with AGAP1 elisa kit
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