NP_001698.2
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NCBI GenBank Nucleotide #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
16,045 Da
NCBI Official Full Name
B-cell CLL/lymphoma 7 protein family member B isoform 1
NCBI Official Synonym Full Names
B-cell CLL/lymphoma 7B
NCBI Protein Information
B-cell CLL/lymphoma 7 protein family member B
UniProt Protein Name
B-cell CLL/lymphoma 7 protein family member B
UniProt Synonym Protein Names
Allergen: Hom s 3
UniProt Entry Name
BCL7B_HUMAN
NCBI Summary for BCL7B
This gene encodes a member of the BCL7 family including BCL7A, BCL7B and BCL7C proteins. This member is BCL7B, which contains a region that is highly similar to the N-terminal segment of BCL7A or BCL7C proteins. The BCL7A protein is encoded by the gene known to be directly involved in a three-way gene translocation in a Burkitt lymphoma cell line. This gene is located at a chromosomal region commonly deleted in Williams syndrome. This gene is highly conserved from C. elegans to human. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Oct 2010]
UniProt Comments for BCL7B
BCL7B: May play a role in lung tumor development or progression. BCL7B is located in the Williams-Beuren syndrome (WBS) critical region. WBS results from a hemizygous deletion of several genes on chromosome 7q11.23, thought to arise as a consequence of unequal crossing over between highly homologous low-copy repeat sequences flanking the deleted region. Haploinsufficiency of BCL7B may be the cause of certain cardiovascular and musculo-skeletal abnormalities observed in the disease. Belongs to the BCL7 family. 3 isoforms of the human protein are produced by alternative splicing.
Chromosomal Location of Human Ortholog: 7q11.23
Molecular Function: actin binding
Research Articles on BCL7B
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Products associated with BCL7B elisa kit
Diseases associated with BCL7B elisa kit
Organs/Tissues associated with BCL7B elisa kit
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