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CD79B elisa kit :: Human B cell antigen receptor complex associated protein beta chain (CD79B) ELISA Kit

Scan QR to view Datasheet Catalog #    MBS7251529 CD79B elisa kit
Unit / Price
48-Strip-Wells  /  $470 +1 FREE 8GB USB
96-Strip-Wells  /  $675 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,925 +3 FREE 8GB USB
10x96-Strip-Wells  /  $5,490 +6 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

B cell antigen receptor complex associated protein beta chain (CD79B), ELISA Kit

 Also Known As   

Human B cell antigen receptor complex associated protein beta chain (CD79B) ELISA Kit

 Product Synonym Names    Human B cell antigen receptor complex associated protein b chain (CD79B) ELISA Kit
 Product Gene Name   

CD79B elisa kit

[Similar Products]
 Product Synonym Gene Name    CD79B [Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Request for Current Manual Insert    Request Current Manual
 OMIM    gene 612692
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 Species Reactivity    Human
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 Preparation and Storage    Store all reagents at 2-8 degree C.
 Sample Preparation    We suggest pre-experimenting with neat (undiluted) samples, 1:2 or 1:4 dilutions. Please avoid diluting your samples more than 1:10 as it would exceed the dilution limit set for this kit. If the expected concentration of the target is beyond the detection range of the kit, please contact our technical support team
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of CD79B elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for CD79B purchase    MBS7251529 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the B cell antigen receptor complex associated protein beta chain (CD79B) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing CD79B. The ELISA analytical biochemical technique of the MBS7251529 kit is based on CD79B antibody-CD79B antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect CD79B antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, CD79B. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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 Product Categories/Family for CD79B elisa kit    Immunology
NCBI/Uniprot data below describe general gene information for CD79B. It may not necessarily be applicable to this product.
 NCBI GI #    11038676
 NCBI GeneID    974
 NCBI Accession #    NP_067613.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_021602.2 [Other Products]
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 UniProt Secondary Accession #    Q53FS2; Q9BU06 [Other Products]
 UniProt Related Accession #    P40259 [Other Products]
 Molecular Weight    26,119 Da
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 NCBI Official Full Name    B-cell antigen receptor complex-associated protein beta chain isoform 2
 NCBI Official Synonym Full Names    CD79b molecule, immunoglobulin-associated beta
 NCBI Official Symbol    CD79B [Similar Products]
 NCBI Official Synonym Symbols   
B29; IGB; AGM6
[Similar Products]
 NCBI Protein Information    B-cell antigen receptor complex-associated protein beta chain; Ig-beta; B-cell-specific glycoprotein B29; immunoglobulin-associated B29 protein; CD79b antigen (immunoglobulin-associated beta)
 UniProt Protein Name    B-cell antigen receptor complex-associated protein beta chain
 UniProt Synonym Protein Names   
B-cell-specific glycoprotein B29; Ig-beta; Immunoglobulin-associated B29 protein; CD_antigen: CD79b
 Protein Family    B-cell antigen receptor complex-associated protein
 UniProt Gene Name    CD79B [Similar Products]
 UniProt Synonym Gene Names    B29; IGB [Similar Products]
 UniProt Entry Name    CD79B_HUMAN
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 NCBI Summary for CD79B    The B lymphocyte antigen receptor is a multimeric complex that includes the antigen-specific component, surface immunoglobulin (Ig). Surface Ig non-covalently associates with two other proteins, Ig-alpha and Ig-beta, which are necessary for expression and function of the B-cell antigen receptor. This gene encodes the Ig-beta protein of the B-cell antigen component. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008]
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 UniProt Comments for CD79B    Ig-beta: Required in cooperation with CD79A for initiation of the signal transduction cascade activated by the B-cell antigen receptor complex (BCR) which leads to internalization of the complex, trafficking to late endosomes and antigen presentation. Enhances phosphorylation of CD79A, possibly by recruiting kinases which phosphorylate CD79A or by recruiting proteins which bind to CD79A and protect it from dephosphorylation. Defects in CD79B are the cause of agammaglobulinemia type 6 (AGM6). It is a primary immunodeficiency characterized by profoundly low or absent serum antibodies and low or absent circulating B-cells due to an early block of B-cell development. Affected individuals develop severe infections in the first years of life. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral; Receptor, misc.

Chromosomal Location of Human Ortholog: 17q23

Cellular Component: nucleoplasm; Golgi apparatus; integral to plasma membrane; cytoplasm; plasma membrane; B cell receptor complex; external side of plasma membrane

Molecular Function: transmembrane receptor activity

Biological Process: B cell receptor signaling pathway; immune response; signal transduction

Disease: Agammaglobulinemia 6, Autosomal Recessive
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 Research Articles on CD79B    1. results suggest that MYD88 mutations, and to a lesser extent CD79B mutations, are important drivers of lymphomagenesis in PTL
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with CD79B elisa kitPathways associated with CD79B elisa kit
 Reference Product  PubMed Publications
 CD79A elisa kit  >608 publications with CD79B and CD79A
 CD19 elisa kit  >106 publications with CD79B and CD19
 CD22 elisa kit  >70 publications with CD79B and CD22
 PTPRC elisa kit  >49 publications with CD79B and PTPRC
 SYK elisa kit  >37 publications with CD79B and SYK
 LYN elisa kit  >23 publications with CD79B and LYN
 FYN elisa kit  >10 publications with CD79B and FYN
 BTK elisa kit  >9 publications with CD79B and BTK
 PTPN6 elisa kit  >4 publications with CD79B and PTPN6
 BLK elisa kit  >4 publications with CD79B and BLK
 Products by Pathway  Pathway Diagram
 Adaptive Immune System Pathway antibodies  Adaptive Immune System Pathway Diagram
 Antigen Activates B Cell Receptor (BCR) Leading To Generation Of Second Messengers Pathway antibodies  Antigen Activates B Cell Receptor (BCR) Leading To Generation Of Second Messengers Pathway Diagram
 B Cell Receptor Signaling Pathway antibodies  B Cell Receptor Signaling Pathway Diagram
 B Cell Receptor Signaling Pathway antibodies  B Cell Receptor Signaling Pathway Diagram
 B Cell Receptor Signaling Pathway antibodies  B Cell Receptor Signaling Pathway Diagram
 BCR Signaling Pathway antibodies  BCR Signaling Pathway Diagram
 Immune System Pathway antibodies  Immune System Pathway Diagram
 Signaling By The B Cell Receptor (BCR) Pathway antibodies  Signaling By The B Cell Receptor (BCR) Pathway Diagram
Diseases associated with CD79B elisa kitOrgans/Tissues associated with CD79B elisa kit
 Disease Name  Pubmed Publications
 Lymphoma, Large B-Cell, Diffuse Antibodies  >75 publications with CD79B and Lymphoma, Large B-Cell, Diffuse
 Liver Diseases Antibodies  >18 publications with CD79B and Liver Diseases
 Inflammation Antibodies  >17 publications with CD79B and Inflammation
 Hyperplasia Antibodies  >16 publications with CD79B and Hyperplasia
 Lung Diseases Antibodies  >11 publications with CD79B and Lung Diseases
 Necrosis Antibodies  >10 publications with CD79B and Necrosis
 Disease Models, Animal Antibodies  >10 publications with CD79B and Disease Models, Animal
 Liver Neoplasms Antibodies  >9 publications with CD79B and Liver Neoplasms
 Anemia Antibodies  >7 publications with CD79B and Anemia
 Weight Loss Antibodies  >5 publications with CD79B and Weight Loss
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >413 publications with CD79B and Blood
 Bone Antibodies  >121 publications with CD79B and Bone
 Lymph Node Antibodies  >89 publications with CD79B and Lymph Node
 Lymph Antibodies  >85 publications with CD79B and Lymph
 Spleen Antibodies  >53 publications with CD79B and Spleen
 Skin Antibodies  >39 publications with CD79B and Skin
 Intestine Antibodies  >23 publications with CD79B and Intestine
 Lung Antibodies  >19 publications with CD79B and Lung
 Thymus Antibodies  >19 publications with CD79B and Thymus
 Vascular Antibodies  >17 publications with CD79B and Vascular
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