NP_001722.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
19,209 Da
NCBI Official Full Name
protein BTG1
NCBI Official Synonym Full Names
B-cell translocation gene 1, anti-proliferative
NCBI Protein Information
protein BTG1; B-cell translocation gene 1 protein
UniProt Protein Name
Protein BTG1
UniProt Synonym Protein Names
B-cell translocation gene 1 protein
UniProt Entry Name
BTG1_HUMAN
NCBI Summary for BTG1
This gene is a member of an anti-proliferative gene family that regulates cell growth and differentiation. Expression of this gene is highest in the G0/G1 phases of the cell cycle and downregulated when cells progressed through G1. The encoded protein interacts with several nuclear receptors, and functions as a coactivator of cell differentiation. This locus has been shown to be involved in a t(8;12)(q24;q22) chromosomal translocation in a case of B-cell chronic lymphocytic leukemia. [provided by RefSeq, Oct 2008]
UniProt Comments for BTG1
BTG1: Anti-proliferative protein. A chromosomal aberration involving BTG1 may be a cause of a form of B-cell chronic lymphocytic leukemia. Translocation t(8;12)(q24;q22) with MYC. Belongs to the BTG family.
Protein type: Oncoprotein; Cell cycle regulation
Chromosomal Location of Human Ortholog: 12q22
Cellular Component: cytoplasm; nucleus
Molecular Function: protein binding; enzyme binding; transcription cofactor activity; kinase binding
Biological Process: negative regulation of cell proliferation; cell migration; positive regulation of angiogenesis; positive regulation of endothelial cell differentiation; regulation of transcription, DNA-dependent; negative regulation of cell growth; positive regulation of myoblast differentiation
Research Articles on BTG1
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Products associated with BTG1 elisa kit
Pathways associated with BTG1 elisa kit
Diseases associated with BTG1 elisa kit
Organs/Tissues associated with BTG1 elisa kit
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