NP_001706.2
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
57,706 Da
NCBI Official Full Name
tyrosine-protein kinase Blk
NCBI Official Synonym Full Names
BLK proto-oncogene, Src family tyrosine kinase
NCBI Official Synonym Symbols
NCBI Protein Information
tyrosine-protein kinase Blk; p55-Blk; b lymphocyte kinase; B lymphoid tyrosine kinase; BLK nonreceptor tyrosine kinase
UniProt Protein Name
Tyrosine-protein kinase Blk
UniProt Synonym Protein Names
B lymphocyte kinase; p55-Blk
UniProt Entry Name
BLK_HUMAN
NCBI Summary for BLK
This gene encodes a nonreceptor tyrosine-kinase of the src family of proto-oncogenes that are typically involved in cell proliferation and differentiation. The protein has a role in B-cell receptor signaling and B-cell development. The protein also stimulates insulin synthesis and secretion in response to glucose and enhances the expression of several pancreatic beta-cell transcription factors. [provided by RefSeq, Aug 2010]
UniProt Comments for BLK
BLK: a nonreceptor tyrosine kinase of the Src family. Expressed predominantly in B lymphocytes
Protein type: Protein kinase, tyrosine (non-receptor); Kinase, protein; Protein kinase, TK; EC 2.7.10.2; TK group; Src family
Chromosomal Location of Human Ortholog: 8p23-p22
Cellular Component: extrinsic to internal side of plasma membrane
Molecular Function: protein binding; protein-tyrosine kinase activity; non-membrane spanning protein tyrosine kinase activity; ATP binding; receptor binding
Biological Process: B cell receptor signaling pathway; positive regulation of insulin secretion; innate immune response; transmembrane receptor protein tyrosine kinase signaling pathway; T cell differentiation; regulation of cell proliferation
Disease: Maturity-onset Diabetes Of The Young, Type 11
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Products associated with BLK elisa kit
Pathways associated with BLK elisa kit
Diseases associated with BLK elisa kit
Organs/Tissues associated with BLK elisa kit
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