NP_004273.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
23,772 Da
NCBI Official Full Name
BAG family molecular chaperone regulator 2
NCBI Official Synonym Full Names
BCL2-associated athanogene 2
NCBI Protein Information
BAG family molecular chaperone regulator 2; bcl-2-associated athanogene 2; BAG-family molecular chaperone regulator-2; dJ417I1.2 (BAG-family molecular chaperone regulator 2)
UniProt Protein Name
BAG family molecular chaperone regulator 2
UniProt Synonym Protein Names
Bcl-2-associated athanogene 2
UniProt Synonym Gene Names
UniProt Entry Name
BAG2_HUMAN
NCBI Summary for BAG2
BAG proteins compete with Hip for binding to the Hsc70/Hsp70 ATPase domain and promote substrate release. All the BAG proteins have an approximately 45-amino acid BAG domain near the C terminus but differ markedly in their N-terminal regions. The predicted BAG2 protein contains 211 amino acids. The BAG domains of BAG1, BAG2, and BAG3 interact specifically with the Hsc70 ATPase domain in vitro and in mammalian cells. All 3 proteins bind with high affinity to the ATPase domain of Hsc70 and inhibit its chaperone activity in a Hip-repressible manner. [provided by RefSeq, Jul 2008]
UniProt Comments for BAG2
BAG2: Inhibits the chaperone activity of HSP70/HSC70 by promoting substrate release.
Protein type: Apoptosis
Chromosomal Location of Human Ortholog: 6p12.1-p11.2
Molecular Function: identical protein binding; protein binding; chaperone binding
Biological Process: protein folding; protein metabolic process
Research Articles on BAG2
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Products associated with BAG2 elisa kit
Pathways associated with BAG2 elisa kit
Diseases associated with BAG2 elisa kit
Organs/Tissues associated with BAG2 elisa kit
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