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BCL2L1/BCL-X elisa kit :: Human BCL2L1/BCL-X ELISA Kit

Scan QR to view Datasheet Catalog #    MBS2510447
Typical Testing Data/Standard Curve (for reference only)
Unit / Price
48-Strip-Wells  /  $410 +1 FREE 8GB USB
96-Strip-Wells  /  $490 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,040 +2 FREE 8GB USB
10x96-Strip-Wells  /  $3,590 +4 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

BCL2L1/BCL-X, ELISA Kit

★Popular Item★
 Also Known As   

Human BCL2L1/BCL-X (Bcl-2 Like Protein 1) ELISA Kit

 Product Gene Name   

BCL2L1/BCL-X elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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  Sample Manual Insert    Download PDF Manual View PDF Manual
 Request for Current Manual Insert    Request Current Manual
 OMIM    600039
 3D Structure    ModBase 3D Structure for Q07817
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 Species Reactivity    Human
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 Specificity    This assay has high sensitivity and excellent specificity for detection of Human BCL2L1/BCL-X. No significant cross-reactivity or interference between Human BCL2L1/BCL-X and analogues was observed. Note: Limited by current skills and knowledge, it is impossible for us to complete the cross- reactivity detection between Human BCL2L1/BCL-X and all the analogues, therefore, cross reaction may still exist.
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 Samples    Serum, Plasma, Biological Fluids
 Assay Type    Sandwich
 Detection Range    0.313--20ng/mL
 Sensitivity    0.188ng/mL
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 Preparation and Storage    Store at 4 degree C.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of BCL2L1/BCL-X elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for BCL2L1/BCL-X purchase    MBS2510447 is a ready-to-use microwell, strip plate Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the BCL2L1/BCL-X, ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range of 0.313--20ng/mL in biological research samples containing BCL2L1/BCL-X, with an estimated sensitivity of 0.188ng/mL. The ELISA analytical biochemical technique of the MBS2510447 kit is based on BCL2L1/BCL-X antibody-BCL2L1/BCL-X antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect BCL2L1/BCL-X antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, BCL2L1/BCL-X. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions such as Serum, Plasma, Biological Fluids. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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Related Product Information for BCL2L1/BCL-X elisa kit

   Description: The kit is a sandwich enzyme immunoassay for in vitro quantitative measurement of BCL2L1/BCL-X in human serum, plasma and other biological fluids
Principle of the Assay: This ELISA kit uses Sandwich-ELISA as the method. The micro ELISA plate provided in this kit has been pre-coated with an antibody specific to Human BCL2L1/BCL-X. Standards or samples are added to the appropriate micro ELISA plate wells and bound by the specific antibody. Then a biotinylated detection antibody specific for Human BCL2L1/BCL-X and Avidin-Horseradish Peroxidase (HRP) conjugate is added to each micro plate well successively and incubated. Free components are washed away. The substrate solution is added to each well. Only those wells that contain Human BCL2L1/BCL-X, biotinylated detection antibody and Avidin-HRP conjugate will appear blue in color. The enzyme-substrate reaction is terminated by the addition of a sulphuric acid solution and the color turns yellow. The optical density (OD) is measured spectrophotometrically at a wavelength of 450 nm +/- 2 nm. The OD value is proportional to the concentration of Human BCL2L1/BCL-X. You can calculate the concentration of Human BCL2L1/BCL-X in the samples by comparing the OD of the samples to the standard curve.
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 Typical Testing Data/Standard Curve (for reference only) of BCL2L1/BCL-X elisa kit    BCL2L1/BCL-X elisa kit Typical Testing Data/Standard Curve (for reference only) image
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Sample Manual Insert of MBS2510447. Click to request current manual
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NCBI/Uniprot data below describe general gene information for BCL2L1/BCL-X. It may not necessarily be applicable to this product.
 NCBI GI #    4502381
 NCBI GeneID    598
 NCBI Accession #    NP_001182.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001191.2 [Other Products]
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 UniProt Primary Accession #    Q07817 [Other Products]
 UniProt Secondary Accession #    Q5CZ89; Q5TE65; Q92976; E1P5L6 [Other Products]
 UniProt Related Accession #    Q07817 [Other Products]
 Molecular Weight    25,290 Da
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 NCBI Official Full Name    bcl-2-like protein 1 isoform 2
 NCBI Official Synonym Full Names    BCL2-like 1
 NCBI Official Symbol    BCL2L1 [Similar Products]
 NCBI Official Synonym Symbols   
BCLX; BCL2L; BCLXL; BCLXS; Bcl-X; bcl-xL; bcl-xS; PPP1R52; BCL-XL/S
[Similar Products]
 NCBI Protein Information    bcl-2-like protein 1; apoptosis regulator Bcl-X; protein phosphatase 1, regulatory subunit 52
 UniProt Protein Name    Bcl-2-like protein 1
 UniProt Synonym Protein Names   
Apoptosis regulator Bcl-X
 UniProt Gene Name    BCL2L1 [Similar Products]
 UniProt Synonym Gene Names    BCL2L; BCLX; Bcl2-L-1 [Similar Products]
 UniProt Entry Name    B2CL1_HUMAN
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 NCBI Summary for BCL2L1/BCL-X    The protein encoded by this gene belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. The proteins encoded by this gene are located at the outer mitochondrial membrane, and have been shown to regulate outer mitochondrial membrane channel (VDAC) opening. VDAC regulates mitochondrial membrane potential, and thus controls the production of reactive oxygen species and release of cytochrome C by mitochondria, both of which are the potent inducers of cell apoptosis. Two alternatively spliced transcript variants, which encode distinct isoforms, have been reported. The longer isoform acts as an apoptotic inhibitor and the shorter form acts as an apoptotic activator. [provided by RefSeq, Jul 2008]
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 UniProt Comments for BCL2L1/BCL-X    Bcl-xL: an antiapoptotic member of the Bcl-2 family. Located at the outer mitochondrial membrane and regulates outer mitochondrial membrane channel (VDAC) opening. VDAC regulates mitochondrial membrane potential, and thus controls the production of reactive oxygen species and release of cytochrome C by mitochondria, both of which are potent inducers of cell apoptosis. Two alternatively spliced isoforms have been reported.

Protein type: Autophagy; Membrane protein, integral; Mitochondrial; Apoptosis

Chromosomal Location of Human Ortholog: 20q11.21

Cellular Component: centrosome; mitochondrial outer membrane; nuclear membrane; mitochondrion; synaptic vesicle membrane; mitochondrial matrix; mitochondrial inner membrane; cytoplasm; nucleolus; integral to membrane; cell junction; nucleus; cytosol

Molecular Function: identical protein binding; protein binding; protein homodimerization activity; protein heterodimerization activity; BH3 domain binding; protein kinase binding

Biological Process: negative regulation of autophagy; apoptosis; cytokinesis; cellular process regulating host cell cycle in response to virus; germ cell development; apoptotic mitochondrial changes; regulation of mitochondrial membrane potential; ovarian follicle development; positive regulation of cell proliferation; negative regulation of neuron apoptosis; release of cytochrome c from mitochondria; in utero embryonic development; mitotic cell cycle checkpoint; suppression by virus of host apoptosis; male gonad development; endocytosis; cell proliferation; neuron apoptosis; fertilization; DNA damage response, signal transduction resulting in induction of apoptosis; response to cytokine stimulus; innate immune response; response to cycloheximide; spermatogenesis; regulation of mitochondrial membrane permeability; negative regulation of apoptosis; growth
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 Research Articles on BCL2L1/BCL-X    1. A signaling pathway consisting of PI3K/Akt-NF-kappaB-Bcl-xL regulates macrophage survival during differentiation. In contrast, in differentiated macrophages, Bcl-xL expression is independent of PI3K/Akt activation.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with BCL2L1/BCL-X elisa kitPathways associated with BCL2L1/BCL-X elisa kit
 Reference Product  PubMed Publications
 BAX elisa kit  >2209 publications with BCL2L1/BCL-X and BAX
 BAD elisa kit  >549 publications with BCL2L1/BCL-X and BAD
 BID elisa kit  >343 publications with BCL2L1/BCL-X and BID
 BAK1 elisa kit  >243 publications with BCL2L1/BCL-X and BAK1
 TP53 elisa kit  >65 publications with BCL2L1/BCL-X and TP53
 APAF1 elisa kit  >61 publications with BCL2L1/BCL-X and APAF1
 BECN1 elisa kit  >55 publications with BCL2L1/BCL-X and BECN1
 BIK elisa kit  >50 publications with BCL2L1/BCL-X and BIK
 BBC3 elisa kit  >46 publications with BCL2L1/BCL-X and BBC3
 BCL2L11 elisa kit  >8 publications with BCL2L1/BCL-X and BCL2L11
 Products by Pathway  Pathway Diagram
 Amyotrophic Lateral Sclerosis (ALS) Pathway antibodies  Amyotrophic Lateral Sclerosis (ALS) Pathway Diagram
 Amyotrophic Lateral Sclerosis (ALS) Pathway antibodies  Amyotrophic Lateral Sclerosis (ALS) Pathway Diagram
 Amyotrophic Lateral Sclerosis (ALS) Pathway antibodies  Amyotrophic Lateral Sclerosis (ALS) Pathway Diagram
 Apoptosis Pathway antibodies  Apoptosis Pathway Diagram
 Apoptosis Pathway antibodies  Apoptosis Pathway Diagram
 Apoptosis Pathway antibodies  Apoptosis Pathway Diagram
 Apoptosis Pathway antibodies  Apoptosis Pathway Diagram
 Apoptosis Modulation And Signaling Pathway antibodies  Apoptosis Modulation And Signaling Pathway Diagram
 BH3-only Proteins Associate With And Inactivate Anti-apoptotic BCL-2 Members Pathway antibodies  BH3-only Proteins Associate With And Inactivate Anti-apoptotic BCL-2 Members Pathway Diagram
 Chronic Myeloid Leukemia Pathway antibodies  Chronic Myeloid Leukemia Pathway Diagram
Diseases associated with BCL2L1/BCL-X elisa kitOrgans/Tissues associated with BCL2L1/BCL-X elisa kit
 Disease Name  Pubmed Publications
 Carcinoma Antibodies  >844 publications with BCL2L1/BCL-X and Carcinoma
 Necrosis Antibodies  >657 publications with BCL2L1/BCL-X and Necrosis
 Nervous System Diseases Antibodies  >381 publications with BCL2L1/BCL-X and Nervous System Diseases
 Gastrointestinal Diseases Antibodies  >297 publications with BCL2L1/BCL-X and Gastrointestinal Diseases
 Brain Diseases Antibodies  >295 publications with BCL2L1/BCL-X and Brain Diseases
 Breast Neoplasms Antibodies  >267 publications with BCL2L1/BCL-X and Breast Neoplasms
 Liver Diseases Antibodies  >251 publications with BCL2L1/BCL-X and Liver Diseases
 Neoplasms, Experimental Antibodies  >232 publications with BCL2L1/BCL-X and Neoplasms, Experimental
 Inflammation Antibodies  >189 publications with BCL2L1/BCL-X and Inflammation
 Liver Neoplasms Antibodies  >188 publications with BCL2L1/BCL-X and Liver Neoplasms
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >1328 publications with BCL2L1/BCL-X and Blood
 Brain Antibodies  >542 publications with BCL2L1/BCL-X and Brain
 Liver Antibodies  >434 publications with BCL2L1/BCL-X and Liver
 Lung Antibodies  >308 publications with BCL2L1/BCL-X and Lung
 Bone Antibodies  >273 publications with BCL2L1/BCL-X and Bone
 Vascular Antibodies  >265 publications with BCL2L1/BCL-X and Vascular
 Muscle Antibodies  >235 publications with BCL2L1/BCL-X and Muscle
 Prostate Antibodies  >199 publications with BCL2L1/BCL-X and Prostate
 Heart Antibodies  >194 publications with BCL2L1/BCL-X and Heart
 Kidney Antibodies  >168 publications with BCL2L1/BCL-X and Kidney
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