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BMP-1 elisa kit :: Human BMP-1 ELISA Kit

Scan QR to view Datasheet Catalog #    MBS2508469 (SPECIAL PROMOTIONAL PRICING for a limited time)
Typical Testing Data/Standard Curve (for reference only)
Unit / Price
48-Strip-Wells  /  $310 +1 FREE 8GB USB
96-Strip-Wells  /  $355 +1 FREE 8GB USB
5x96-Strip-Wells  /  $1,435 +1 FREE 8GB USB
10x96-Strip-Wells  /  $2,805 +3 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

BMP-1, ELISA Kit

★Popular Item★
 Also Known As   

Human BMP-1 (Bone Morphogenetic Protein 1) ELISA Kit

 Product Gene Name   

BMP-1 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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  Sample Manual Insert    Download PDF Manual View PDF Manual
 Request for Current Manual Insert    Request Current Manual
 OMIM    112264
 3D Structure    ModBase 3D Structure for P13497
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 Species Reactivity    Human
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 Specificity    This assay has high sensitivity and excellent specificity for detection of Human BMP-1. No significant cross-reactivity or interference between Human BMP-1 and analogues was observed. Note: Limited by current skills and knowledge, it is impossible for us to complete the cross- reactivity detection between Human BMP-1 and all the analogues, therefore, cross reaction may still exist.
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 Samples    Serum, Plasma, Biological Fluids
 Assay Type    Sandwich
 Detection Range    0.156-10ng/mL
 Sensitivity    Min: 0.094ng/mL; Max: 10ng/mL
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 Preparation and Storage    Store at 4 degree C.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of BMP-1 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for BMP-1 purchase    MBS2508469 is a ready-to-use microwell, strip plate Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the BMP-1, ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range of 0.156-10ng/mL in biological research samples containing BMP-1, with an estimated sensitivity of Min: 0.094ng/mL; Max: 10ng/mL. The ELISA analytical biochemical technique of the MBS2508469 kit is based on BMP-1 antibody-BMP-1 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect BMP-1 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, BMP-1. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions such as Serum, Plasma, Biological Fluids. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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Related Product Information for BMP-1 elisa kit

   Description: The kit is a sandwich enzyme immunoassay for in vitro quantitative measurement of BMP-1 in human serum, plasma and other biological fluids
Principle of the Assay: This ELISA kit uses Sandwich-ELISA as the method. The micro ELISA plate provided in this kit has been pre-coated with an antibody specific to Human BMP-1. Standards or samples are added to the appropriate micro ELISA plate wells and bound by the specific antibody. Then a biotinylated detection antibody specific for Human BMP-1 and Avidin-Horseradish Peroxidase (HRP) conjugate is added to each micro plate well successively and incubated. Free components are washed away. The substrate solution is added to each well. Only those wells that contain Human BMP-1, biotinylated detection antibody and Avidin-HRP conjugate will appear blue in color. The enzyme-substrate reaction is terminated by the addition of a sulphuric acid solution and the color turns yellow. The optical density (OD) is measured spectrophotometrically at a wavelength of 450 nm +/- 2 nm. The OD value is proportional to the concentration of Human BMP-1. You can calculate the concentration of Human BMP-1 in the samples by comparing the OD of the samples to the standard curve.
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 Typical Testing Data/Standard Curve (for reference only) of BMP-1 elisa kit    BMP-1 elisa kit Typical Testing Data/Standard Curve (for reference only) image
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Sample Manual Insert of MBS2508469. Click to request current manual
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NCBI/Uniprot data below describe general gene information for BMP-1. It may not necessarily be applicable to this product.
 NCBI GI #    619861
 NCBI GeneID    649
 NCBI Accession #    AAC41710.1 [Other Products]
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 UniProt Primary Accession #    P13497 [Other Products]
 UniProt Secondary Accession #    Q13292; Q13872; Q14874; Q99421; Q99422; Q99423; Q9UL38; A8K6F5; B2RN46; D3DSR0 [Other Products]
 UniProt Related Accession #    P13497 [Other Products]
 Molecular Weight    92,655 Da
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 NCBI Official Full Name    bone morphogenetic protein, partial
 NCBI Official Synonym Full Names    bone morphogenetic protein 1
 NCBI Official Symbol    BMP1 [Similar Products]
 NCBI Official Synonym Symbols   
PCP; TLD; OI13; PCP2; PCOLC
[Similar Products]
 NCBI Protein Information    bone morphogenetic protein 1; mammalian tolloid protein; procollagen C-endopeptidase; procollagen C-proteinase 3
 UniProt Protein Name    Bone morphogenetic protein 1
 UniProt Synonym Protein Names   
Mammalian tolloid protein; mTld; Procollagen C-proteinase; PCP
 UniProt Gene Name    BMP1 [Similar Products]
 UniProt Synonym Gene Names    PCOLC; BMP-1; mTld; PCP [Similar Products]
 UniProt Entry Name    BMP1_HUMAN
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 NCBI Summary for BMP-1    This gene encodes a protein that is capable of inducing formation of cartilage in vivo. Although other bone morphogenetic proteins are members of the TGF-beta superfamily, this gene encodes a protein that is not closely related to other known growth factors. This gene is expressed as alternatively spliced variants that share an N-terminal protease domain but differ in their C-terminal region. [provided by RefSeq, Aug 2008]
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 UniProt Comments for BMP-1    BMP1: Cleaves the C-terminal propeptides of procollagen I, II and III. Induces cartilage and bone formation. May participate in dorsoventral patterning during early development by cleaving chordin (CHRD). Defects in BMP1 are a cause of autosomal recessive osteogenesis imperfecta (AR-OI). A connective tissue disorder characterized by bone fragility, progressively deforming bones, bowing of limbs due to multiple fractures, very short stature, a triangular face, severe scoliosis, and grayish sclera. AR-OI due to BMP1 mutations belongs to the group of osteogenesis imperfecta type III in the Sillence classification. Belongs to the peptidase M12A family. 7 isoforms of the human protein are produced by alternative splicing.

Protein type: EC 3.4.24.19; Cytokine; Protease

Chromosomal Location of Human Ortholog: 8p21.3

Cellular Component: Golgi apparatus; proteinaceous extracellular matrix; extracellular space; extracellular region

Molecular Function: peptidase activity; growth factor activity; metallopeptidase activity; zinc ion binding; metalloendopeptidase activity; cytokine activity; calcium ion binding

Biological Process: extracellular matrix disassembly; extracellular matrix organization and biogenesis; ossification; multicellular organismal development; lipoprotein metabolic process; proteolysis; cell differentiation; skeletal development; cartilage condensation

Disease: Osteogenesis Imperfecta, Type Xiii
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 Research Articles on BMP-1    1. High BMP1 expression is associated with type-1 diabetes.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with BMP-1 elisa kitPathways associated with BMP-1 elisa kit
 Reference Product  PubMed Publications
 PCOLCE elisa kit  >18 publications with BMP-1 and PCOLCE
 TLL1 elisa kit  >15 publications with BMP-1 and TLL1
 PRL elisa kit  >2 publications with BMP-1 and PRL
 PTH elisa kit  >1 publications with BMP-1 and PTH
 CHRD elisa kit  >1 publications with BMP-1 and CHRD
 Products by Pathway  Pathway Diagram
 Adipogenesis Pathway antibodies  Adipogenesis Pathway Diagram
 Anchoring Fibril Formation Pathway antibodies  Anchoring Fibril Formation Pathway Diagram
 Assembly Of Collagen Fibrils And Other Multimeric Structures Pathway antibodies  Assembly Of Collagen Fibrils And Other Multimeric Structures Pathway Diagram
 Cardiac Progenitor Differentiation Pathway antibodies  Cardiac Progenitor Differentiation Pathway Diagram
 Collagen Biosynthesis And Modifying Enzymes Pathway antibodies  Collagen Biosynthesis And Modifying Enzymes Pathway Diagram
 Collagen Formation Pathway antibodies  Collagen Formation Pathway Diagram
 Crosslinking Of Collagen Fibrils Pathway antibodies  Crosslinking Of Collagen Fibrils Pathway Diagram
 Degradation Of The Extracellular Matrix Pathway antibodies  Degradation Of The Extracellular Matrix Pathway Diagram
 Extracellular Matrix Organization Pathway antibodies  Extracellular Matrix Organization Pathway Diagram
 HDL-mediated Lipid Transport Pathway antibodies  HDL-mediated Lipid Transport Pathway Diagram
Diseases associated with BMP-1 elisa kitOrgans/Tissues associated with BMP-1 elisa kit
 Disease Name  Pubmed Publications
 Fibrosis Antibodies  >23 publications with BMP-1 and Fibrosis
 Disease Models, Animal Antibodies  >12 publications with BMP-1 and Disease Models, Animal
 Nervous System Diseases Antibodies  >7 publications with BMP-1 and Nervous System Diseases
 Neoplasm Metastasis Antibodies  >6 publications with BMP-1 and Neoplasm Metastasis
 Kidney Diseases Antibodies  >5 publications with BMP-1 and Kidney Diseases
 Breast Neoplasms Antibodies  >4 publications with BMP-1 and Breast Neoplasms
 Inflammation Antibodies  >4 publications with BMP-1 and Inflammation
 Lung Neoplasms Antibodies  >4 publications with BMP-1 and Lung Neoplasms
 Myocardial Infarction Antibodies  >4 publications with BMP-1 and Myocardial Infarction
 Neoplasms, Experimental Antibodies  >3 publications with BMP-1 and Neoplasms, Experimental
 Organ/Tissue Name  Pubmed Publications
 Bone Antibodies  >243 publications with BMP-1 and Bone
 Connective Tissue Antibodies  >39 publications with BMP-1 and Connective Tissue
 Embryonic Tissue Antibodies  >27 publications with BMP-1 and Embryonic Tissue
 Muscle Antibodies  >21 publications with BMP-1 and Muscle
 Kidney Antibodies  >17 publications with BMP-1 and Kidney
 Vascular Antibodies  >16 publications with BMP-1 and Vascular
 Bone Marrow Antibodies  >16 publications with BMP-1 and Bone Marrow
 Heart Antibodies  >15 publications with BMP-1 and Heart
 Skin Antibodies  >15 publications with BMP-1 and Skin
 Mouth Antibodies  >13 publications with BMP-1 and Mouth
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