View our list of available Coronavirus (COVID-19, SARS-CoV-2, 2019-nCOV) antibodies, recombinant proteins, ELISA Kits... Options Full Datasheet Printer Friendly Datasheet Prepare for Printing Full Datasheet Printer Friendly Datasheet Prepare for Printing Have Questions? Ask Us! Request A Quote Today! Add To Compare List BMP2 elisa kit :: Human BMP-2 ELISA Kit Catalog # MBS175918 Unit / Price 96-Strip-Wells / $510 +1 FREE 8GB USB 5x96-Strip-Wells / $2,305 +2 FREE 8GB USB Product Name Product Info Accession #s Product Desc Diseases/Tissues/Pathways Applications References Product Name BMP-2 (BMP2), ELISA Kit Popular Item Full Product Name Human BMP-2 PicoKine ELISA Kit Product Synonym Names Bone morphogenetic protein 2; bone morphogenetic protein 2; BDA2; BMP-2; BMP-2A; Bmp2; BMP2_HUMAN; BMP2A; Bone morphogenetic protein 2; Bone morphogenetic protein 2A Product Gene Name BMP2 elisa kit[Similar Products] Research Use Only For Research Use Only. Not for use in diagnostic procedures. TOP Sample Manual Insert Download Sample PDF Manual View Sample PDF Manual 3D Structure ModBase 3D Structure for C8C060 Species Reactivity Human Specificity Natural and recombinant Human BMP2 Samples Bone tissue, cell culture supernates and serum Detection Range 31.2pg/ml-2000pg/ml Sensitivity <2pg/ml Intra-assay Precision Intra-Assay Precision (Precision within an assay): Three samples of known concentration were tested on one plate to assess intra-assay precision. Inter-assay Precision Inter-Assay Precision (Precision across assays):Three samples of known concentration were tested in separate assays to assess interassay precision. Preparation and Storage Store at 4 degree C for 6 months, at -20 degree C for 12 months. Avoid multiple freeze-thaw cycles (Shipped with wet ice.) Production Time Due to severe delay and raw materials shortage, production time may takes between 5-8 weeks. ISO Certification Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory. Product Note Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details. Other Notes Small volumes of BMP2 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply. Searchable Terms for BMP2 purchase MBS175918 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the BMP-2 (BMP2) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing BMP2. The ELISA analytical biochemical technique of the MBS175918 kit is based on BMP2 antibody-BMP2 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect BMP2 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, BMP2. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%). TOP Related Product Information for BMP2 elisa kit Principle of the Assay: The Picokine Human BMP2 Pre-Coated ELISA (Enzyme-Linked Immunosorbent Assay) kit is a solid phase immunoassay specially designed to measure Human BMP2 with a 96-well strip plate that is pre-coated with antibody specific for BMP2. The detection antibody is a biotinylated antibody specific for BMP2. The capture antibody is monoclonal antibody from mouse, the detection antibody is monoclonal antibody from mouse. The kit contains recombinant Human BMP2 with immunogen: Expression system for standard: CHO; Immunogen sequence: Q283-R396. The kit is analytically validated with ready to use reagents. To measure Human BMP2, add standards and samples to the wells, then add the biotinylated detection antibody. Wash the wells with PBS or TBS buffer, and add Avidin-Biotin-Peroxidase Complex (ABC-HRP). Wash away the unbounded ABC-HRP with PBS or TBS buffer and add TMB. TMB is substrate to HRP and will be catalyzed to produce a blue color product, which changes into yellow after adding acidic stop solution. The density of the yellow product is linearly proportional to Human BMP2 in the sample. Read the density of the yellow product in each well using a plate reader, and benchmark the sample wells' readings against the standard curve to determine the concentration of Human BMP2 in the sample.Background/Introduction: Bone morphogenetic protein-2(BMP-2, BMP 2A) belongs to the transforming growth factor beta(TGF-beta) superfamily. It is thought to be involved in cartilage and bone formation during embryogenesis, but may have additional functions in morphogenesis as implied by its expression in various organs and embryonic tissues of mice.1 BMP-2 has been identified as a candidate mediator of retinoid activity. BMP-2 protein induces medulloblastoma cell apoptosis, whereas the BMP-2 antagonist noggin blocks both retinoid and BMP-2-induced apoptosis. BMP-2 also induces p38 mitogen-activated protein kinase(MAPK), which is necessary for BMP-2 and retinoid-induced apoptosis.2 Bone morphogenic proteins(BMPs) are known to promote osteogenesis, and clinical trials are currently underway to evaluate the ability of certain BMPs to promote fracture-healing and spinal fusion.3 The standard product used in this kit is recombinant human BMP-2, constituting dimer by two chains of 114 amino acids with the molecular mass of 26KDa. Typical Testing Data/Standard Curve (for reference only) of BMP2 elisa kit TOP Sample Manual Insert of MBS175918. NCBI/Uniprot data below describe general gene information for BMP2. It may not necessarily be applicable to this product. NCBI GeneID 650 UniProt Primary Accession # C8C060 [Other Products] UniProt Related Accession # P12643[Other Products] Molecular Weight 44,702 Da TOP NCBI Official Synonym Full Names bone morphogenetic protein 2 NCBI Official Symbol BMP2 [Similar Products] NCBI Official Synonym Symbols BDA2; BMP2A [Similar Products] NCBI Protein Information bone morphogenetic protein 2; BMP-2A; bone morphogenetic protein 2A UniProt Protein Name Bone morphogenetic protein 2 UniProt Synonym Protein Names Bone morphogenetic protein 2 Protein Family Bone morphogenetic protein UniProt Gene Name BMP2 [Similar Products] UniProt Entry Name C8C060_HUMAN TOP NCBI Summary for BMP2 The protein encoded by this gene belongs to the transforming growth factor-beta (TGFB) superfamily. The encoded protein acts as a disulfide-linked homodimer and induces bone and cartilage formation. [provided by RefSeq, Jul 2008] TOP Research Articles on BMP2 1. Recombinant human rhBMP-2 use and location of rhBMP-2 use in adult spinal deformity surgery, at reported doses, do not increase acute major, neurological, or wound complications. TOP Precautions All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines. Disclaimer While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information. TOP Pathways associated with BMP2 elisa kit Products by Pathway Pathway Diagram Adipogenesis Pathway antibodies Adipogenesis Pathway Diagram BDNF Signaling Pathway antibodies BDNF Signaling Pathway Diagram BMP Signalling And Regulation Pathway antibodies BMP Signalling And Regulation Pathway Diagram Basal Cell Carcinoma Pathway antibodies Basal Cell Carcinoma Pathway Diagram Basal Cell Carcinoma Pathway antibodies Basal Cell Carcinoma Pathway Diagram Cytokine-cytokine Receptor Interaction Pathway antibodies Cytokine-cytokine Receptor Interaction Pathway Diagram Cytokine-cytokine Receptor Interaction Pathway antibodies Cytokine-cytokine Receptor Interaction Pathway Diagram Elastic Fibre Formation Pathway antibodies Elastic Fibre Formation Pathway Diagram Extracellular Matrix Organization Pathway antibodies Extracellular Matrix Organization Pathway Diagram Heart Development Pathway antibodies Heart Development Pathway Diagram Diseases associated with BMP2 elisa kit Disease Name Pubmed Publications Bone Diseases Antibodies >558 publications with BMP2 and Bone Diseases Necrosis Antibodies >110 publications with BMP2 and Necrosis Inflammation Antibodies >90 publications with BMP2 and Inflammation Pain Antibodies >46 publications with BMP2 and Pain Hypertrophy Antibodies >44 publications with BMP2 and Hypertrophy Hypertension Antibodies >41 publications with BMP2 and Hypertension Fibrosis Antibodies >33 publications with BMP2 and Fibrosis Breast Neoplasms Antibodies >31 publications with BMP2 and Breast Neoplasms Kidney Diseases Antibodies >29 publications with BMP2 and Kidney Diseases Atherosclerosis Antibodies >25 publications with BMP2 and Atherosclerosis Organs/Tissues associated with BMP2 elisa kit Organ/Tissue Name Pubmed Publications Bone Antibodies >4109 publications with BMP2 and Bone Connective Tissue Antibodies >633 publications with BMP2 and Connective Tissue Embryonic Tissue Antibodies >448 publications with BMP2 and Embryonic Tissue Heart Antibodies >188 publications with BMP2 and Heart Brain Antibodies >157 publications with BMP2 and Brain Kidney Antibodies >90 publications with BMP2 and Kidney Lung Antibodies >79 publications with BMP2 and Lung Liver Antibodies >69 publications with BMP2 and Liver Eye Antibodies >62 publications with BMP2 and Eye Uterus Antibodies >28 publications with BMP2 and Uterus TOP © 2006-24 MyBioSource.com. 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