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BMP-7 elisa kit :: Human Bone Morphogenetic Protein 7 (BMP-7) ELISA Kit

Scan QR to view Datasheet Catalog #    MBS266416
Typical Testing Data/Standard Curve (for reference only)
Unit / Price
48-Strip-Wells  /  $260 +1 FREE 8GB USB
96-Strip-Wells  /  $405 +1 FREE 8GB USB
5x96-Strip-Wells  /  $1,615 +2 FREE 8GB USB
10x96-Strip-Wells  /  $2,880 +3 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Bone Morphogenetic Protein 7 (BMP-7), ELISA Kit

★Popular Item★
 Also Known As   

Human Bone Morphogenetic Protein 7 (BMP-7) ELISA Kit

 Product Gene Name   

BMP-7 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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  Sample Manual Insert    Download PDF Manual View PDF Manual
 Request for Current Manual Insert    Request Current Manual
 OMIM    112267
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 Species Reactivity    Human
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 Samples    Human serum, plasma or Cell Culture Supernatant and organizations in the natural and recombinant BMP-7 concentration
 Assay Type    Sandwich
 Detection Range    2000 pg/ml-31.2 pg/ml
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 Preparation and Storage    Store all reagents at 2-8 degree C.
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of BMP-7 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for BMP-7 purchase    MBS266416 is a ready-to-use microwell, strip plate Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Bone Morphogenetic Protein 7 (BMP-7) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range of 2000 pg/ml-31.2 pg/ml in biological research samples containing BMP-7. The ELISA analytical biochemical technique of the MBS266416 kit is based on BMP-7 antibody-BMP-7 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect BMP-7 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, BMP-7. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions such as Human serum, plasma or Cell Culture Supernatant and organizations in the natural and recombinant BMP-7 concentration. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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Product Description specifically for BMP-7 elisa kit

   Principle of the Assay: This experiment use double-sandwich elisa technique and the ELISA Kit provided is typical. The pre-coated antibody is human BMP-7 monoclonal antibody and the detecting antibody is polyclonal antibody with biotin labeled. Samples and biotin labeling antibody are added into ELISA plate wells and washed out with PBS or TBS. Then Avidin-peroxidase conjugates are added to ELISA wells in order; Use TMB substrate for coloring after reactant thoroughly washed out by PBS or TBS. TMB turns into blue in peroxidase catalytic and finally turns into yellow under the action of acid. The color depth and the testing factors in samples are positively correlated.
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 Typical Testing Data/Standard Curve (for reference only) of BMP-7 elisa kit    BMP-7 elisa kit Typical Testing Data/Standard Curve (for reference only) image
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Sample Manual Insert of MBS266416. Click to request current manual
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NCBI/Uniprot data below describe general gene information for BMP-7. It may not necessarily be applicable to this product.
 NCBI GI #    4502427
 NCBI GeneID    655
 NCBI Accession #    NP_001710.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001719.2 [Other Products]
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 UniProt Secondary Accession #    Q9H512; Q9NTQ7 [Other Products]
 UniProt Related Accession #    P18075 [Other Products]
 Molecular Weight    49,313 Da
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 NCBI Official Full Name    bone morphogenetic protein 7
 NCBI Official Synonym Full Names    bone morphogenetic protein 7
 NCBI Official Symbol    BMP7 [Similar Products]
 NCBI Official Synonym Symbols   
OP-1
[Similar Products]
 NCBI Protein Information    bone morphogenetic protein 7; osteogenic protein 1
 UniProt Protein Name    Bone morphogenetic protein 7
 UniProt Synonym Protein Names   
Osteogenic protein 1; OP-1; INN: Eptotermin alfa
 Protein Family    Bone morphogenetic protein
 UniProt Gene Name    BMP7 [Similar Products]
 UniProt Synonym Gene Names    OP1; BMP-7; OP-1 [Similar Products]
 UniProt Entry Name    BMP7_HUMAN
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 NCBI Summary for BMP-7    The bone morphogenetic proteins (BMPs) are a family of secreted signaling molecules that can induce ectopic bone growth. Many BMPs are part of the transforming growth factor-beta (TGFB) superfamily. BMPs were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extraskeletal site. Based on its expression early in embryogenesis, the BMP encoded by this gene has a proposed role in early development and possible bone inductive activity. [provided by RefSeq, Jul 2008]
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 UniProt Comments for BMP-7    BMP7: Induces cartilage and bone formation. May be the osteoinductive factor responsible for the phenomenon of epithelial osteogenesis. Plays a role in calcium regulation and bone homeostasis. Homodimer; disulfide-linked. Interacts with SOSTDC1. Interacts with TWSG1. Expressed in the kidney and bladder. Lower levels seen in the brain. Belongs to the TGF-beta family.

Protein type: Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 20q13

Cellular Component: extracellular matrix; extracellular space; extracellular region

Molecular Function: heparin binding; protein binding; growth factor activity; cytokine activity; transforming growth factor beta receptor binding

Biological Process: negative regulation of MAP kinase activity; response to peptide hormone stimulus; axon guidance; extracellular matrix organization and biogenesis; positive regulation of apoptosis; positive regulation of transcription, DNA-dependent; negative regulation of NF-kappaB import into nucleus; embryonic pattern specification; response to estradiol stimulus; negative regulation of cell cycle; regulation of apoptosis; BMP signaling pathway; response to vitamin D; epithelial cell differentiation; ureteric bud development; dendrite development; mesonephros development; skeletal development; embryonic limb morphogenesis; ossification; positive regulation of heterotypic cell-cell adhesion; positive regulation of bone mineralization; odontogenesis of dentine-containing teeth; positive regulation of osteoblast differentiation; negative regulation of neuron differentiation; mesenchymal cell differentiation; mesoderm formation; branching morphogenesis of a tube; inhibition of NF-kappaB transcription factor; cartilage development; negative regulation of mitosis; negative regulation of Notch signaling pathway; epithelial to mesenchymal transition; negative regulation of phosphorylation; positive regulation of transcription from RNA polymerase II promoter; steroid hormone mediated signaling; embryonic camera-type eye morphogenesis; negative regulation of transcription, DNA-dependent; metanephros development; neurite morphogenesis; growth
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 Research Articles on BMP-7    1. BMP5 and BMP7, involved in cardiomyocyte differentiation defect
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with BMP-7 elisa kitPathways associated with BMP-7 elisa kit
 Reference Product  PubMed Publications
 BMPR2 elisa kit  >112 publications with BMP-7 and BMPR2
 BMPR1A elisa kit  >69 publications with BMP-7 and BMPR1A
 SMAD5 elisa kit  >41 publications with BMP-7 and SMAD5
 BMPR1B elisa kit  >23 publications with BMP-7 and BMPR1B
 ACVR1 elisa kit  >21 publications with BMP-7 and ACVR1
 ACVR2A elisa kit  >5 publications with BMP-7 and ACVR2A
 SOSTDC1 elisa kit  >4 publications with BMP-7 and SOSTDC1
 SMAD9 elisa kit  >3 publications with BMP-7 and SMAD9
 FST elisa kit  >3 publications with BMP-7 and FST
 NOG elisa kit  >3 publications with BMP-7 and NOG
 Products by Pathway  Pathway Diagram
 ALK2 Signaling Events Pathway antibodies  ALK2 Signaling Events Pathway Diagram
 BMP Receptor Signaling Pathway antibodies  BMP Receptor Signaling Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Elastic Fibre Formation Pathway antibodies  Elastic Fibre Formation Pathway Diagram
 Endochondral Ossification Pathway antibodies  Endochondral Ossification Pathway Diagram
 Extracellular Matrix Organization Pathway antibodies  Extracellular Matrix Organization Pathway Diagram
 Hippo Signaling Pathway antibodies  Hippo Signaling Pathway Diagram
 Hippo Signaling Pathway antibodies  Hippo Signaling Pathway Diagram
 Molecules Associated With Elastic Fibres Pathway antibodies  Molecules Associated With Elastic Fibres Pathway Diagram
Diseases associated with BMP-7 elisa kitOrgans/Tissues associated with BMP-7 elisa kit
 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >131 publications with BMP-7 and Neoplasms
 Disease Models, Animal Antibodies  >87 publications with BMP-7 and Disease Models, Animal
 Kidney Diseases Antibodies  >82 publications with BMP-7 and Kidney Diseases
 Nervous System Diseases Antibodies  >51 publications with BMP-7 and Nervous System Diseases
 Cardiovascular Diseases Antibodies  >44 publications with BMP-7 and Cardiovascular Diseases
 Inflammation Antibodies  >39 publications with BMP-7 and Inflammation
 Necrosis Antibodies  >31 publications with BMP-7 and Necrosis
 Bone Resorption Antibodies  >30 publications with BMP-7 and Bone Resorption
 Renal Insufficiency Antibodies  >28 publications with BMP-7 and Renal Insufficiency
 Hypertension Antibodies  >26 publications with BMP-7 and Hypertension
 Organ/Tissue Name  Pubmed Publications
 Bone Antibodies  >1219 publications with BMP-7 and Bone
 Kidney Antibodies  >180 publications with BMP-7 and Kidney
 Embryonic Tissue Antibodies  >163 publications with BMP-7 and Embryonic Tissue
 Connective Tissue Antibodies  >140 publications with BMP-7 and Connective Tissue
 Brain Antibodies  >99 publications with BMP-7 and Brain
 Muscle Antibodies  >93 publications with BMP-7 and Muscle
 Mouth Antibodies  >83 publications with BMP-7 and Mouth
 Eye Antibodies  >67 publications with BMP-7 and Eye
 Prostate Antibodies  >35 publications with BMP-7 and Prostate
 Heart Antibodies  >33 publications with BMP-7 and Heart
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