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CCL5 elisa kit :: Human C-C motif chemokine 5 ELISA Kit

Scan QR to view Datasheet Catalog #    MBS2886866 CCL5 elisa kit
Unit / Price
48-Strip-Wells  /  $325 +1 FREE 8GB USB
96-Strip-Wells  /  $435 +1 FREE 8GB USB
5x96-Strip-Wells  /  $1,825 +2 FREE 8GB USB
10x96-Strip-Wells  /  $3,290 +4 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

C-C motif chemokine 5 (CCL5), ELISA Kit

★Popular Item★
 Also Known As   

Human C-C motif chemokine 5 ELISA Kit

 Product Synonym Names    C-C motif chemokine 5; EoCP; Eosinophil chemotactic cytokine; SIS-delta; Small-inducible cytokine A5; T cell-specific protein P228; TCP228; T-cell-specific protein RANTES; CCL5; D17S136E
 Product Gene Name   

CCL5 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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  Sample Manual Insert    Download PDF Manual View PDF Manual
 Request for Current Manual Insert    Request Current Manual
 MBS2886866 Testing Data    Testing Data PDF
 OMIM    187011
 3D Structure    ModBase 3D Structure for P13501
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 Species Reactivity    Human
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 Assay Type    Sandwich
 Detection Range    78-5000 pg/mL
 Sensitivity    23pg/mL
 Intra-Assay CV    <=4.7%
 Inter-Assay CV    <=8.1%
 Recovery    98%
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 Preparation and Storage    For long term storage, please store the entire kit at -20 degree C.
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of CCL5 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for CCL5 purchase    MBS2886866 is a ready-to-use microwell, strip plate Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the C-C motif chemokine 5 (CCL5) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range of 78-5000 pg/mL in biological research samples containing CCL5, with an estimated sensitivity of 23pg/mL. The ELISA analytical biochemical technique of the MBS2886866 kit is based on CCL5 antibody-CCL5 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect CCL5 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, CCL5. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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Sample Manual Insert of MBS2886866. Click to request current manual
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NCBI/Uniprot data below describe general gene information for CCL5. It may not necessarily be applicable to this product.
 NCBI GI #    22538814
 NCBI GeneID    6352
 NCBI Accession #    NP_002976.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_002985.2 [Other Products]
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 UniProt Primary Accession #    P13501 [Other Products]
 UniProt Secondary Accession #    O43646; Q0QVW8; Q4ZGJ1; Q9NYA2; Q9UBG2; Q9UC99 [Other Products]
 UniProt Related Accession #    P13501 [Other Products]
 Molecular Weight    9,990 Da
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 NCBI Official Full Name    C-C motif chemokine 5 isoform 1
 NCBI Official Synonym Full Names    C-C motif chemokine ligand 5
 NCBI Official Symbol    CCL5 [Similar Products]
 NCBI Official Synonym Symbols   
SISd; eoCP; SCYA5; RANTES; TCP228; D17S136E; SIS-delta
[Similar Products]
 NCBI Protein Information    C-C motif chemokine 5
 UniProt Protein Name    C-C motif chemokine 5
 UniProt Synonym Protein Names   
EoCP; Eosinophil chemotactic cytokine; SIS-delta; Small-inducible cytokine A5; T cell-specific protein P228; TCP228
 Protein Family    C-C motif chemokine
 UniProt Gene Name    CCL5 [Similar Products]
 UniProt Synonym Gene Names    D17S136E; SCYA5; TCP228 [Similar Products]
 UniProt Entry Name    CCL5_HUMAN
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 NCBI Summary for CCL5    This gene is one of several chemokine genes clustered on the q-arm of chromosome 17. Chemokines form a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of the N-terminal cysteine residues of the mature peptide. This chemokine, a member of the CC subfamily, functions as a chemoattractant for blood monocytes, memory T helper cells and eosinophils. It causes the release of histamine from basophils and activates eosinophils. This cytokine is one of the major HIV-suppressive factors produced by CD8+ cells. It functions as one of the natural ligands for the chemokine receptor chemokine (C-C motif) receptor 5 (CCR5), and it suppresses in vitro replication of the R5 strains of HIV-1, which use CCR5 as a coreceptor. Alternative splicing results in multiple transcript variants that encode different isoforms. [provided by RefSeq, Jul 2013]
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 UniProt Comments for CCL5    CCL5: Chemoattractant for blood monocytes, memory T-helper cells and eosinophils. Causes the release of histamine from basophils and activates eosinophils. Binds to CCR1, CCR3, CCR4 and CCR5. One of the major HIV-suppressive factors produced by CD8+ T- cells. Recombinant RANTES protein induces a dose-dependent inhibition of different strains of HIV-1, HIV-2, and simian immunodeficiency virus (SIV). The processed form RANTES(3-68) acts as a natural chemotaxis inhibitor and is a more potent inhibitor of HIV-1-infection. The second processed form RANTES(4-68) exhibits reduced chemotactic and HIV-suppressive activity compared with RANTES(1-68) and RANTES(3-68) and is generated by an unidentified enzyme associated with monocytes and neutrophils. By mitogens. T-cell and macrophage specific. Belongs to the intercrine beta (chemokine CC) family.

Protein type: Secreted, signal peptide; Cell adhesion; Secreted; Motility/polarity/chemotaxis; Chemokine

Chromosomal Location of Human Ortholog: 17q12

Cellular Component: cytoplasm; extracellular region; extracellular space

Molecular Function: CCR1 chemokine receptor binding; CCR4 chemokine receptor binding; CCR5 chemokine receptor binding; chemoattractant activity; chemokine activity; chemokine receptor antagonist activity; chemokine receptor binding; heparin binding; phosphoinositide phospholipase C activity; phospholipase activator activity; protein binding; protein homodimerization activity; protein kinase activity; protein self-association; receptor signaling protein tyrosine kinase activator activity

Biological Process: aging; calcium ion transport; cell-cell signaling; cellular calcium ion homeostasis; cellular protein complex assembly; chemotaxis; chronic inflammatory response; dendritic cell chemotaxis; dibenzo-p-dioxin metabolic process; eosinophil chemotaxis; exocytosis; G-protein coupled receptor protein signaling pathway; inflammatory response; leukocyte adhesion; lipopolysaccharide-mediated signaling pathway; lymphocyte chemotaxis; macrophage chemotaxis; MAPKKK cascade; monocyte chemotaxis; negative regulation of G-protein coupled receptor protein signaling pathway; negative regulation of viral genome replication; neutrophil activation; neutrophil chemotaxis; phospholipase D activation; positive chemotaxis; positive regulation of angiogenesis; positive regulation of calcium ion transport; positive regulation of cell adhesion; positive regulation of cell migration; positive regulation of cell-cell adhesion mediated by integrin; positive regulation of cellular biosynthetic process; positive regulation of epithelial cell proliferation; positive regulation of fever; positive regulation of GTPase activity; positive regulation of homotypic cell-cell adhesion; positive regulation of inflammatory response; positive regulation of innate immune response; positive regulation of JAK-STAT cascade; positive regulation of neuron differentiation; positive regulation of osteoclast differentiation; positive regulation of phosphoinositide 3-kinase cascade; positive regulation of phosphorylation; positive regulation of smooth muscle cell migration; positive regulation of smooth muscle cell proliferation; positive regulation of T cell proliferation; positive regulation of translational initiation; positive regulation of tyrosine phosphorylation of STAT protein; positive regulation of viral genome replication; protein kinase B signaling cascade; protein tetramerization; regulation of chronic inflammatory response; regulation of insulin secretion; regulation of T cell activation; response to activity; response to drug; response to estrogen stimulus; response to glucocorticoid stimulus; response to insulin stimulus; response to salt stress; response to toxin; response to virus
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 Research Articles on CCL5    1. The Interaction of Heparin Tetrasaccharides with Chemokine CCL5 Is Modulated by Sulfation Pattern and pH.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with CCL5 elisa kitPathways associated with CCL5 elisa kit
 Reference Product  PubMed Publications
 CCL2 elisa kit  >1483 publications with CCL5 and CCL2
 CCR5 elisa kit  >1056 publications with CCL5 and CCR5
 CXCL10 elisa kit  >700 publications with CCL5 and CXCL10
 CCR1 elisa kit  >321 publications with CCL5 and CCR1
 CXCL9 elisa kit  >263 publications with CCL5 and CXCL9
 CCR2 elisa kit  >240 publications with CCL5 and CCR2
 CCR3 elisa kit  >203 publications with CCL5 and CCR3
 CXCR3 elisa kit  >159 publications with CCL5 and CXCR3
 CCR4 elisa kit  >93 publications with CCL5 and CCR4
 IL8 elisa kit  >90 publications with CCL5 and IL8
 Products by Pathway  Pathway Diagram
 Chagas Disease (American Trypanosomiasis) Pathway antibodies  Chagas Disease (American Trypanosomiasis) Pathway Diagram
 Chagas Disease (American Trypanosomiasis) Pathway antibodies  Chagas Disease (American Trypanosomiasis) Pathway Diagram
 Chemokine Receptors Bind Chemokines Pathway antibodies  Chemokine Receptors Bind Chemokines Pathway Diagram
 Chemokine Signaling Pathway antibodies  Chemokine Signaling Pathway Diagram
 Chemokine Signaling Pathway antibodies  Chemokine Signaling Pathway Diagram
 Class A/1 (Rhodopsin-like Receptors) Pathway antibodies  Class A/1 (Rhodopsin-like Receptors) Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Cytosolic DNA-sensing Pathway antibodies  Cytosolic DNA-sensing Pathway Diagram
 Cytosolic DNA-sensing Pathway antibodies  Cytosolic DNA-sensing Pathway Diagram
Diseases associated with CCL5 elisa kitOrgans/Tissues associated with CCL5 elisa kit
 Disease Name  Pubmed Publications
 Inflammation Antibodies  >1774 publications with CCL5 and Inflammation
 Necrosis Antibodies  >950 publications with CCL5 and Necrosis
 Lung Diseases Antibodies  >500 publications with CCL5 and Lung Diseases
 Asthma Antibodies  >378 publications with CCL5 and Asthma
 Cardiovascular Diseases Antibodies  >328 publications with CCL5 and Cardiovascular Diseases
 Kidney Diseases Antibodies  >172 publications with CCL5 and Kidney Diseases
 Fibrosis Antibodies  >164 publications with CCL5 and Fibrosis
 Liver Diseases Antibodies  >152 publications with CCL5 and Liver Diseases
 Atherosclerosis Antibodies  >150 publications with CCL5 and Atherosclerosis
 Heart Diseases Antibodies  >129 publications with CCL5 and Heart Diseases
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >2886 publications with CCL5 and Blood
 Lung Antibodies  >619 publications with CCL5 and Lung
 Brain Antibodies  >373 publications with CCL5 and Brain
 Kidney Antibodies  >291 publications with CCL5 and Kidney
 Bone Antibodies  >270 publications with CCL5 and Bone
 Skin Antibodies  >263 publications with CCL5 and Skin
 Muscle Antibodies  >227 publications with CCL5 and Muscle
 Liver Antibodies  >222 publications with CCL5 and Liver
 Lymph Node Antibodies  >147 publications with CCL5 and Lymph Node
 Intestine Antibodies  >98 publications with CCL5 and Intestine
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