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CRP elisa kit :: Human C-reactive protein ELISA Kit

Scan QR to view Datasheet Catalog #    MBS2886290 CRP elisa kit
Unit / Price
48-Strip-Wells  /  $280 +1 FREE 8GB USB
96-Strip-Wells  /  $345 +1 FREE 8GB USB
5x96-Strip-Wells  /  $1,410 +1 FREE 8GB USB
10x96-Strip-Wells  /  $2,480 +3 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

C-reactive protein (CRP), ELISA Kit

★Popular Item★
 Also Known As   

Human C-reactive protein ELISA Kit

 Product Synonym Names    C-reactive protein; CRP; PTX1
 Product Gene Name   

CRP elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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  Sample Manual Insert    Download PDF Manual View PDF Manual
 Request for Current Manual Insert    Request Current Manual
 MBS2886290 Testing Data    Testing Data PDF
 OMIM    123260
 3D Structure    ModBase 3D Structure for P02741
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 Species Reactivity    Human
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 Assay Type    Sandwich
 Detection Range    0.156-10 ng/mL
 Sensitivity    0.067ng/mL
 Intra-Assay CV    <=5.3%
 Inter-Assay CV    <=7.8%
 Recovery    82%
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 Preparation and Storage    For long term storage, please store the entire kit at -20 degree C.
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of CRP elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for CRP purchase    MBS2886290 is a ready-to-use microwell, strip plate Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the C-reactive protein (CRP) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range of 0.156-10 ng/mL in biological research samples containing CRP, with an estimated sensitivity of 0.067ng/mL. The ELISA analytical biochemical technique of the MBS2886290 kit is based on CRP antibody-CRP antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect CRP antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, CRP. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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Related Product Information for CRP elisa kit

   Intended Uses: This immunoassay kit allows for the in vitro quantitative determination of target antigen concentrations in serum, plasma, tissue homogenates, cell culture supernates or other biological fluids.

Principle of the Assay: The microtiter plate provided in this kit has been pre-coated with an antibody specific to target antigen. Standards or samples are then added to the appropriate microtiter plate wells with a biotin-conjugated antibody preparation specific for target antigen and then avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. Then a TMB substrate solution is added to each well. Only those wells that contain target antigen, biotin-conjugated antibody and enzyme-conjugated Avidin will exhibit a change in color. The enzyme-substrate reaction is terminated by the addition of a sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450 nm ▒ 2 nm. The concentration of target antigen in the samples is then determined by comparing the O.D. of the samples to the standard curve.
Sample Manual Insert of MBS2886290. Click to request current manual
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NCBI/Uniprot data below describe general gene information for CRP. It may not necessarily be applicable to this product.
 NCBI GI #    55770842
 NCBI GeneID    1401
 NCBI Accession #    NP_000558.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_000567.2 [Other Products]
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 UniProt Primary Accession #    P02741 [Other Products]
 UniProt Secondary Accession #    Q08AK3; Q8WW75; A8K078; D3DVD9; D3DVE0 [Other Products]
 UniProt Related Accession #    P02741 [Other Products]
 Molecular Weight    10,415 Da
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 NCBI Official Full Name    C-reactive protein
 NCBI Official Synonym Full Names    C-reactive protein, pentraxin-related
 NCBI Official Symbol    CRP [Similar Products]
 NCBI Official Synonym Symbols   
PTX1
[Similar Products]
 NCBI Protein Information    C-reactive protein
 UniProt Protein Name    C-reactive protein
 Protein Family    Cryparin
 UniProt Gene Name    CRP [Similar Products]
 UniProt Synonym Gene Names    PTX1 [Similar Products]
 UniProt Entry Name    CRP_HUMAN
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 NCBI Summary for CRP    The protein encoded by this gene belongs to the pentaxin family. It is involved in several host defense related functions based on its ability to recognize foreign pathogens and damaged cells of the host and to initiate their elimination by interacting with humoral and cellular effector systems in the blood. Consequently, the level of this protein in plasma increases greatly during acute phase response to tissue injury, infection, or other inflammatory stimuli. [provided by RefSeq, Sep 2009]
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 UniProt Comments for CRP    CRP: Displays several functions associated with host defense: it promotes agglutination, bacterial capsular swelling, phagocytosis and complement fixation through its calcium-dependent binding to phosphorylcholine. Can interact with DNA and histones and may scavenge nuclear material released from damaged circulating cells. Belongs to the pentaxin family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 1q23.2

Cellular Component: extracellular region; extracellular space

Molecular Function: calcium ion binding; choline binding; complement component C1q binding; low-density lipoprotein binding; low-density lipoprotein receptor binding; protein binding; virion binding

Biological Process: acute-phase response; defense response to Gram-positive bacterium; inflammatory response; negative regulation of vasodilation; opsonization; positive regulation of superoxide release
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 Research Articles on CRP    1. CRP suppresses expression of N-cadherin (p < 0.01), a mesenchymal marker of EMT, and ZEB-1, an EMT-related transcription factor (p < 0.01). These findings suggest that CRP inhibits EMT in a MCA-38 tumor-bearing mouse model.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with CRP elisa kitPathways associated with CRP elisa kit
 Reference Product  PubMed Publications
 STAT3 elisa kit  >40 publications with CRP and STAT3
 APCS elisa kit  >12 publications with CRP and APCS
 C1S elisa kit  >12 publications with CRP and C1S
 C1R elisa kit  >12 publications with CRP and C1R
 LEP elisa kit  >11 publications with CRP and LEP
 FCGR2B elisa kit  >8 publications with CRP and FCGR2B
 FCGR2A elisa kit  >7 publications with CRP and FCGR2A
 C1QB elisa kit  >2 publications with CRP and C1QB
 Products by Pathway  Pathway Diagram
 Classical Antibody-mediated Complement Activation Pathway antibodies  Classical Antibody-mediated Complement Activation Pathway Diagram
 Complement Cascade Pathway antibodies  Complement Cascade Pathway Diagram
 Creation Of C4 And C2 Activators Pathway antibodies  Creation Of C4 And C2 Activators Pathway Diagram
 IL6-mediated Signaling Events Pathway antibodies  IL6-mediated Signaling Events Pathway Diagram
 Immune System Pathway antibodies  Immune System Pathway Diagram
 Initial Triggering Of Complement Pathway antibodies  Initial Triggering Of Complement Pathway Diagram
 Innate Immune System Pathway antibodies  Innate Immune System Pathway Diagram
 Selenium Pathway antibodies  Selenium Pathway Diagram
Diseases associated with CRP elisa kitOrgans/Tissues associated with CRP elisa kit
 Disease Name  Pubmed Publications
 Inflammation Antibodies  >13119 publications with CRP and Inflammation
 Cardiovascular Diseases Antibodies  >9270 publications with CRP and Cardiovascular Diseases
 Infection Antibodies  >5114 publications with CRP and Infection
 Heart Diseases Antibodies  >4420 publications with CRP and Heart Diseases
 Metabolic Diseases Antibodies  >4279 publications with CRP and Metabolic Diseases
 Necrosis Antibodies  >3626 publications with CRP and Necrosis
 Myocardial Ischemia Antibodies  >3509 publications with CRP and Myocardial Ischemia
 Atherosclerosis Antibodies  >3106 publications with CRP and Atherosclerosis
 Obesity Antibodies  >2297 publications with CRP and Obesity
 Arthritis, Rheumatoid Antibodies  >2266 publications with CRP and Arthritis, Rheumatoid
 Organ/Tissue Name  Pubmed Publications
 Liver Antibodies  >1617 publications with CRP and Liver
 Pancreas Antibodies  >179 publications with CRP and Pancreas
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