NP_001274667.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Related Accession #
Molecular Weight
15,597 Da
NCBI Official Full Name
CCAAT/enhancer-binding protein beta isoform b
NCBI Official Synonym Full Names
CCAAT/enhancer binding protein (C/EBP), beta
NCBI Official Synonym Symbols
LAP; LIP; CRP2; NF-M; Nfil6; NF-IL6; IL-6DBP; C/EBPbeta [Similar Products]
NCBI Protein Information
CCAAT/enhancer-binding protein beta
UniProt Protein Name
CCAAT/enhancer-binding protein beta
UniProt Synonym Protein Names
AGP/EBP; Interleukin-6-dependent-binding protein; IL-6DBP; Liver-enriched transcriptional activator; LAP
UniProt Synonym Gene Names
UniProt Entry Name
CEBPB_MOUSE
UniProt Comments for CEBPb
C/EBP-beta: a bZIP transcription factor which can form homodimers or heterodimers with the related proteins CEBP-alpha, -delta and -gamma. Involved in immune and inflammatory responses. Specifically binds to regulatory regions of genes encoding IL-6, other cytokines and several acute-phase proteins. There are two forms of C/EBPbeta, the 38kDa liver activating protein (LAP) and the 20kDa liver inhibitory protein (LIP) which may be products of alternative translation. LAP is a transcriptional activator while LIP may inhibit C/EBPbeta transcriptional activity. Phosphorylated and activated by ERK1/2.
Protein type: Motility/polarity/chemotaxis; Transcription factor; DNA-binding
Cellular Component: nuclear matrix; cytoplasm; nuclear chromatin; nucleus
Molecular Function: RNA polymerase II transcription factor activity, enhancer binding; protein binding; protein homodimerization activity; DNA binding; sequence-specific DNA binding; protein heterodimerization activity; chromatin binding; transcription factor binding; transcription factor activity; glucocorticoid receptor binding
Biological Process: fat cell differentiation; transcription from RNA polymerase II promoter; embryonic placenta development; transcription, DNA-dependent; positive regulation of transcription, DNA-dependent; regulation of interleukin-6 biosynthetic process; mammary gland epithelial cell proliferation; response to lipopolysaccharide; neuron differentiation; positive regulation of osteoblast differentiation; regulation of transcription, DNA-dependent; brown fat cell differentiation; positive regulation of fat cell differentiation; positive regulation of transcription from RNA polymerase II promoter; negative regulation of neuron apoptosis; cell differentiation; negative regulation of transcription, DNA-dependent
Research Articles on CEBPb
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Organs/Tissues associated with CEBPb elisa kit
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