P80098.3
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
11,200 Da
NCBI Official Full Name
C-C motif chemokine 7
NCBI Official Synonym Full Names
chemokine (C-C motif) ligand 7
NCBI Official Synonym Symbols
FIC; MARC; MCP3; NC28; MCP-3; SCYA6; SCYA7 [Similar Products]
NCBI Protein Information
C-C motif chemokine 7; small-inducible cytokine A7; monocyte chemotactic protein 3; monocyte chemoattractant protein 3; small inducible cytokine A7 (monocyte chemotactic protein 3)
UniProt Protein Name
C-C motif chemokine 7
UniProt Synonym Protein Names
Monocyte chemoattractant protein 3; Monocyte chemotactic protein 3; MCP-3; NC28; Small-inducible cytokine A7
UniProt Synonym Gene Names
UniProt Entry Name
CCL7_HUMAN
NCBI Summary for CCL7
This gene encodes monocyte chemotactic protein 3, a secreted chemokine which attracts macrophages during inflammation and metastasis. It is a member of the C-C subfamily of chemokines which are characterized by having two adjacent cysteine residues. The protein is an in vivo substrate of matrix metalloproteinase 2, an enzyme which degrades components of the extracellular matrix. This gene is part of a cluster of C-C chemokine family members on chromosome 17q. [provided by RefSeq, Jul 2008]
UniProt Comments for CCL7
CCL7: Chemotactic factor that attracts monocytes and eosinophils, but not neutrophils. Augments monocyte anti-tumor activity. Also induces the release of gelatinase B. This protein can bind heparin. Binds to CCR1, CCR2 and CCR3. Belongs to the intercrine beta (chemokine CC) family.
Protein type: Secreted; Motility/polarity/chemotaxis; Secreted, signal peptide
Chromosomal Location of Human Ortholog: 17q11.2-q12
Cellular Component: extracellular space; extracellular region
Molecular Function: heparin binding; CCR1 chemokine receptor binding; CCR2 chemokine receptor binding; chemokine activity
Biological Process: cellular calcium ion homeostasis; regulation of cell shape; monocyte chemotaxis; cell-cell signaling; eosinophil chemotaxis; response to gamma radiation; cytoskeleton organization and biogenesis; immune response; chemotaxis; inflammatory response; signal transduction; positive regulation of cell migration
Research Articles on CCL7
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Disclaimer
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Products associated with CCL7 elisa kit
Pathways associated with CCL7 elisa kit
Diseases associated with CCL7 elisa kit
Organs/Tissues associated with CCL7 elisa kit
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