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CD70 elisa kit :: Human CD70 molecule ELISA Kit

Scan QR to view Datasheet Catalog #    MBS911908
Typical Testing Data/Standard Curve (for reference only)
Unit / Price
24-Strip-Wells (Limit 1)  /  $250 +1 FREE 8GB USB
48-Strip-Wells  /  $495 +1 FREE 8GB USB
96-Strip-Wells  /  $710 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,705 +3 FREE 8GB USB
10x96-Strip-Wells  /  $5,145 +6 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

CD70 molecule, ELISA Kit

★Popular Item★
 Also Known As   

Human CD70 antigen, CD70 ELISA Kit

 Product Synonym Names    Human CD70 antigen (CD70) ELISA kit; CD27L; CD27LG; TNFSF7; CD27 ligand; CD70 antigen; Ki-24 antigen; surface antigen CD70; tumor necrosis factor (ligand) superfamily; member 7; tumor necrosis factor ligand superfamily; member 7; CD70 molecule
 Product Gene Name   

CD70 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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  Sample Manual Insert    Download PDF Manual View PDF Manual
 Request for Current Manual Insert    Request Current Manual
 MBS911908 Testing Data    Testing Data PDF
 OMIM    602840
 3D Structure    ModBase 3D Structure for P32970
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 Species Reactivity    Human
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 Specificity    This assay has high sensitivity and excellent specificity for detection of human CD70. No significant cross-reactivity or interference between human CD70 and analogues was observed.
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 Samples    Serum, plasma, tissue homogenates, cell lysates.
 Assay Type    Sandwich
 Detection Range    0.156 ng/ml -10 ng/ml.
 Sensitivity    0.039 ng /ml.
 Intra-assay Precision    Intra-assay Precision (Precision within an assay): CV%<8%. Three samples of known concentration were tested twenty times on one plate to assess.
 Inter-assay Precision    Inter-assay Precision (Precision between assays): CV%<10%. Three samples of known concentration were tested in twenty assays to assess.
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 Preparation and Storage    Unopened test kits should be stored at 2 to 8 degree C upon receipt. Please refer to pdf manual for further storage instructions.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of CD70 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for CD70 purchase    MBS911908 is a ready-to-use microwell, strip plate Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the CD70 molecule, ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range of 0.156 ng/ml -10 ng/ml in biological research samples containing CD70, with an estimated sensitivity of 0.039 ng /ml. The ELISA analytical biochemical technique of the MBS911908 kit is based on CD70 antibody-CD70 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect CD70 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, CD70. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions such as Serum, plasma, tissue homogenates, cell lysates. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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Related Product Information for CD70 elisa kit

   Principle of the Assay||This assay employs the quantitative sandwich enzyme immunoassay technique. Antibody specific for CD70 has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and any CD70 present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for CD70 is added to the wells. After washing, avidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of CD70 bound in the initial step. The color development is stopped and the intensity of the color is measured.
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 Typical Testing Data/Standard Curve (for reference only) of CD70 elisa kit    CD70 elisa kit Typical Testing Data/Standard Curve (for reference only) image
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Sample Manual Insert of MBS911908. Click to request current manual
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NCBI/Uniprot data below describe general gene information for CD70. It may not necessarily be applicable to this product.
 NCBI GI #    4507605
 NCBI GeneID    970
 NCBI Accession #    NP_001243.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001252.4 [Other Products]
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 UniProt Primary Accession #    P32970 [Other Products]
 UniProt Secondary Accession #    Q53XX4; Q96J57 [Other Products]
 UniProt Related Accession #    P32970 [Other Products]
 Molecular Weight    21,118 Da
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 NCBI Official Full Name    CD70 antigen
 NCBI Official Synonym Full Names    CD70 molecule
 NCBI Official Symbol    CD70 [Similar Products]
 NCBI Official Synonym Symbols   
CD27L; CD27LG; TNFSF7
[Similar Products]
 NCBI Protein Information    CD70 antigen; CD27-L; CD27 ligand; Ki-24 antigen; surface antigen CD70; tumor necrosis factor ligand superfamily member 7; tumor necrosis factor (ligand) superfamily, member 7
 UniProt Protein Name    CD70 antigen
 UniProt Synonym Protein Names   
CD27 ligand; CD27-L; Tumor necrosis factor ligand superfamily member 7; CD_antigen: CD70
 Protein Family    CD70 antigen
 UniProt Gene Name    CD70 [Similar Products]
 UniProt Synonym Gene Names    CD27L; CD27LG; TNFSF7; CD27-L [Similar Products]
 UniProt Entry Name    CD70_HUMAN
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 NCBI Summary for CD70    The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for TNFRSF27/CD27. It is a surface antigen on activated, but not on resting, T and B lymphocytes. It induces proliferation of costimulated T cells, enhances the generation of cytolytic T cells, and contributes to T cell activation. This cytokine is also reported to play a role in regulating B-cell activation, cytotoxic function of natural killer cells, and immunoglobulin sythesis. [provided by RefSeq, Jul 2008]
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 UniProt Comments for CD70    CD70: Cytokine that binds to CD27. Plays a role in T-cell activation. Induces the proliferation of costimulated T-cells and enhances the generation of cytolytic T-cells. Belongs to the tumor necrosis factor family.

Protein type: Cytokine; Membrane protein, integral

Chromosomal Location of Human Ortholog: 19p13

Cellular Component: extracellular space; integral to plasma membrane; plasma membrane

Molecular Function: protein binding; protease binding; cytokine activity; tumor necrosis factor receptor binding; receptor binding

Biological Process: cell proliferation; cell-cell signaling; immune response; signal transduction
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 Research Articles on CD70    1. CD70-blocking of alphaDC1s from both controls and patients with chronic lymphocytic leukaemia had a negative influence on the production of both IL-12p70 and the Th1 cytokine IFN-gamma.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with CD70 elisa kitPathways associated with CD70 elisa kit
 Reference Product  PubMed Publications
 CD27 elisa kit  >216 publications with CD70 and CD27
 Products by Pathway  Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
Diseases associated with CD70 elisa kitOrgans/Tissues associated with CD70 elisa kit
 Disease Name  Pubmed Publications
 Necrosis Antibodies  >127 publications with CD70 and Necrosis
 Neoplasms Antibodies  >109 publications with CD70 and Neoplasms
 Carcinoma Antibodies  >29 publications with CD70 and Carcinoma
 Inflammation Antibodies  >28 publications with CD70 and Inflammation
 Death Antibodies  >23 publications with CD70 and Death
 Neoplasms, Experimental Antibodies  >22 publications with CD70 and Neoplasms, Experimental
 Adenocarcinoma Antibodies  >18 publications with CD70 and Adenocarcinoma
 Nervous System Diseases Antibodies  >18 publications with CD70 and Nervous System Diseases
 Cardiovascular Diseases Antibodies  >17 publications with CD70 and Cardiovascular Diseases
 Kidney Diseases Antibodies  >14 publications with CD70 and Kidney Diseases
 Organ/Tissue Name  Pubmed Publications
 Kidney Antibodies  >15 publications with CD70 and Kidney
 Intestine Antibodies  >5 publications with CD70 and Intestine
 Stomach Antibodies  >1 publications with CD70 and Stomach
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