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CD8A elisa kit :: Human CD8a molecule ELISA Kit

Scan QR to view Datasheet Catalog #    MBS701418
Typical Testing Data/Standard Curve (for reference only)
Unit / Price
24-Strip-Wells (LIMIT 1)  /  $250 +1 FREE 8GB USB
48-Strip-Wells  /  $550 +1 FREE 8GB USB
96-Strip-Wells  /  $795 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,890 +3 FREE 8GB USB
10x96-Strip-Wells  /  $5,465 +6 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

CD8a molecule, ELISA Kit

★Popular Item★
 Also Known As   

Human Cluster of differentiation 8, CD8 ELISA Kit

 Product Synonym Names    Human Cluster of differentiation 8; CD8 ELISA Kit; CD8; Leu2; MAL; p32; CD8 antigen alpha polypeptide; CD8 antigen; alpha polypeptide (p32) ; Leu2 T-lymphocyte antigen; OKT8 T-cell antigen; OTTHUMP00000203721; T cell co-receptor; T-cell antigen Leu2; T-cell; CD8a molecule
 Product Gene Name   

CD8A elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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  Sample Manual Insert    Download PDF Manual View PDF Manual
 Request for Current Manual Insert    Request Current Manual
 MBS701418 Testing Data    Testing Data PDF
 OMIM    gene 608957
 3D Structure    ModBase 3D Structure for P01732
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 Species Reactivity    Human
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 Specificity    This assay has high sensitivity and excellent specificity for detection of human CD8. No significant cross-reactivity or interference between human CD8 and analogues was observed.
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 Samples    Serum, plasma, cell culture supernates, tissue homogenates.
 Assay Type    Sandwich (Quantitative)
 Detection Range    62.5 U/ml-4000 U/ml.
 Sensitivity    15.6 U/ml.
 Intra-assay Precision    Intra-assay Precision (Precision within an assay): CV%<8%. Three samples of known concentration were tested twenty times on one plate to assess.
 Inter-assay Precision    Inter-assay Precision (Precision between assays): CV%<10%. Three samples of known concentration were tested in twenty assays to assess.
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 Preparation and Storage    Unopened test kits should be stored at 2 to 8 degree C upon receipt. Please refer to pdf manual for further storage instructions.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of CD8A elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for CD8A purchase    MBS701418 is a ready-to-use microwell, strip plate Sandwich (Quantitative) ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the CD8a molecule, ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range of 62.5 U/ml-4000 U/ml in biological research samples containing CD8A, with an estimated sensitivity of 15.6 U/ml. The ELISA analytical biochemical technique of the MBS701418 kit is based on CD8A antibody-CD8A antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect CD8A antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, CD8A. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions such as Serum, plasma, cell culture supernates, tissue homogenates. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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Related Product Information for CD8A elisa kit

   Principle of the Assay: This assay employs the quantitative sandwich enzyme immunoassay technique. Antibody specific for CD8 has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and any CD8 present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for CD8 is added to the wells. After washing, avidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of CD8 bound in the initial step. The color development is stopped and the intensity of the color is measured.
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 Typical Testing Data/Standard Curve (for reference only) of CD8A elisa kit    CD8A elisa kit Typical Testing Data/Standard Curve (for reference only) image
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Sample Manual Insert of MBS701418. Click to request current manual
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NCBI/Uniprot data below describe general gene information for CD8A. It may not necessarily be applicable to this product.
 NCBI GI #    225007536
 NCBI GeneID    925
 NCBI Accession #    NP_001139345.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001145873.1 [Other Products]
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 UniProt Primary Accession #    P01732 [Other Products]
 UniProt Secondary Accession #    Q13970; Q4ZG17; B4DT80; D6W5M8 [Other Products]
 UniProt Related Accession #    P01732 [Other Products]
 Molecular Weight    25,729 Da
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 NCBI Official Full Name    T-cell surface glycoprotein CD8 alpha chain isoform 1
 NCBI Official Synonym Full Names    CD8a molecule
 NCBI Official Symbol    CD8A [Similar Products]
 NCBI Official Synonym Symbols   
CD8; MAL; p32; Leu2
[Similar Products]
 NCBI Protein Information    T-cell surface glycoprotein CD8 alpha chain; T8 T-cell antigen; T cell co-receptor; OKT8 T-cell antigen; T-cell antigen Leu2; Leu2 T-lymphocyte antigen; CD8 antigen, alpha polypeptide (p32); T-lymphocyte differentiation antigen T8/Leu-2
 UniProt Protein Name    T-cell surface glycoprotein CD8 alpha chain
 UniProt Synonym Protein Names   
T-lymphocyte differentiation antigen T8/Leu-2; CD_antigen: CD8a
 Protein Family    T-cell surface glycoprotein
 UniProt Gene Name    CD8A [Similar Products]
 UniProt Synonym Gene Names    MAL [Similar Products]
 UniProt Entry Name    CD8A_HUMAN
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 NCBI Summary for CD8A    The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen acts as a coreceptor with the T-cell receptor on the T lymphocyte to recognize antigens displayed by an antigen presenting cell in the context of class I MHC molecules. The coreceptor functions as either a homodimer composed of two alpha chains or as a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. This gene encodes the CD8 alpha chain. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011]
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 UniProt Comments for CD8A    Function: Identifies cytotoxic/suppressor T-cells that interact with MHC class I bearing targets. CD8 is thought to play a role in the process of T-cell mediated killing. CD8 alpha chains binds to class I MHC molecules alpha-3 domains.
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 Research Articles on CD8A    1. CD8-positivity proved to be an independent prognostic predictor of worse outcome in pediatric anaplastic lymphoma kinase-positive anaplastic large cell lymphoma.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with CD8A elisa kitPathways associated with CD8A elisa kit
 Reference Product  PubMed Publications
 CD4 elisa kit  >80 publications with CD8A and CD4
 CD8B elisa kit  >19 publications with CD8A and CD8B
 CD3E elisa kit  >6 publications with CD8A and CD3E
 HLA-A elisa kit  >4 publications with CD8A and HLA-A
 CD3D elisa kit  >3 publications with CD8A and CD3D
 LCK elisa kit  >2 publications with CD8A and LCK
 HLA-B elisa kit  >1 publications with CD8A and HLA-B
 Products by Pathway  Pathway Diagram
 Adaptive Immune System Pathway antibodies  Adaptive Immune System Pathway Diagram
 Antigen Processing And Presentation Pathway antibodies  Antigen Processing And Presentation Pathway Diagram
 Antigen Processing And Presentation Pathway antibodies  Antigen Processing And Presentation Pathway Diagram
 Cell Adhesion Molecules (CAMs) Pathway antibodies  Cell Adhesion Molecules (CAMs) Pathway Diagram
 Cell Adhesion Molecules (CAMs) Pathway antibodies  Cell Adhesion Molecules (CAMs) Pathway Diagram
 Downstream Signaling In Naive CD8+ T Cells Pathway antibodies  Downstream Signaling In Naive CD8+ T Cells Pathway Diagram
 Hematopoietic Cell Lineage Pathway antibodies  Hematopoietic Cell Lineage Pathway Diagram
 Hematopoietic Cell Lineage Pathway antibodies  Hematopoietic Cell Lineage Pathway Diagram
 IL12-mediated Signaling Events Pathway antibodies  IL12-mediated Signaling Events Pathway Diagram
 Immune System Pathway antibodies  Immune System Pathway Diagram
Diseases associated with CD8A elisa kitOrgans/Tissues associated with CD8A elisa kit
 Disease Name  Pubmed Publications
 Inflammation Antibodies  >18 publications with CD8A and Inflammation
 Necrosis Antibodies  >12 publications with CD8A and Necrosis
 Cardiovascular Diseases Antibodies  >9 publications with CD8A and Cardiovascular Diseases
 Neoplasms, Experimental Antibodies  >8 publications with CD8A and Neoplasms, Experimental
 Carcinoma Antibodies  >7 publications with CD8A and Carcinoma
 Liver Diseases Antibodies  >6 publications with CD8A and Liver Diseases
 Kidney Diseases Antibodies  >5 publications with CD8A and Kidney Diseases
 Fibrosis Antibodies  >4 publications with CD8A and Fibrosis
 Liver Neoplasms Antibodies  >3 publications with CD8A and Liver Neoplasms
 Heart Diseases Antibodies  >3 publications with CD8A and Heart Diseases
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >84 publications with CD8A and Blood
 Spleen Antibodies  >16 publications with CD8A and Spleen
 Kidney Antibodies  >10 publications with CD8A and Kidney
 Liver Antibodies  >10 publications with CD8A and Liver
 Brain Antibodies  >9 publications with CD8A and Brain
 Thymus Antibodies  >9 publications with CD8A and Thymus
 Intestine Antibodies  >6 publications with CD8A and Intestine
 Lung Antibodies  >4 publications with CD8A and Lung
 Connective Tissue Antibodies  >2 publications with CD8A and Connective Tissue
 Stomach Antibodies  >2 publications with CD8A and Stomach
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