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CDC42BPB elisa kit :: Human CDC42 binding protein kinase beta (DMPK-like) ELISA Kit

Scan QR to view Datasheet Catalog #    MBS9330449 CDC42BPB elisa kit
Unit / Price
48-Strip-Wells  /  $470 +1 FREE 8GB USB
96-Strip-Wells  /  $680 +1 FREE 8GB USB
5x96-Strip-Wells  /  $3,100 +3 FREE 8GB USB
10x96-Strip-Wells  /  $6,095 +7 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

CDC42 binding protein kinase beta (DMPK-like) (CDC42BPB), ELISA Kit

 Also Known As   

Human Serine/threonine-protein kinase MRCK beta, CDC42BPB ELISA Kit

 Product Synonym Names    Human Serine/threonine-protein kinase MRCK beta (CDC42BPB) ELISA kit; KIAA1124; MRCKB; CDC42-binding protein kinase beta; CDC42-binding protein kinase beta (DMPK-like) ; myotonic dystrophy protein kinase-like beta; CDC42 binding protein kinase beta (DMPK-like)
 Product Gene Name   

CDC42BPB elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Request for Current Manual Insert    Request Current Manual
 OMIM    614062
 3D Structure    ModBase 3D Structure for Q9Y5S2
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 Species Reactivity    Human
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 Preparation and Storage    Store all reagents at 2-8 degree C
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of CDC42BPB elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for CDC42BPB purchase    MBS9330449 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the CDC42 binding protein kinase beta (DMPK-like) (CDC42BPB) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing CDC42BPB. The ELISA analytical biochemical technique of the MBS9330449 kit is based on CDC42BPB antibody-CDC42BPB antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect CDC42BPB antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, CDC42BPB. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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NCBI/Uniprot data below describe general gene information for CDC42BPB. It may not necessarily be applicable to this product.
 NCBI GI #    115527097
 NCBI GeneID    9578
 NCBI Accession #    NP_006026.3 [Other Products]
 NCBI GenBank Nucleotide #    NM_006035.3 [Other Products]
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 UniProt Primary Accession #    Q9Y5S2 [Other Products]
 UniProt Secondary Accession #    Q2L7A5; Q86TJ1; Q9ULU5; A9JR72 [Other Products]
 UniProt Related Accession #    Q9Y5S2 [Other Products]
 Molecular Weight    194,315 Da
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 NCBI Official Full Name    serine/threonine-protein kinase MRCK beta
 NCBI Official Synonym Full Names    CDC42 binding protein kinase beta (DMPK-like)
 NCBI Official Symbol    CDC42BPB [Similar Products]
 NCBI Official Synonym Symbols   
MRCKB
[Similar Products]
 NCBI Protein Information    serine/threonine-protein kinase MRCK beta; CDC42BP-beta; DMPK-like beta; myotonic dystrophy protein kinase-like beta; CDC42-binding protein kinase beta (DMPK-like); myotonic dystrophy kinase-related CDC42-binding kinase beta
 UniProt Protein Name    Serine/threonine-protein kinase MRCK beta
 UniProt Synonym Protein Names   
CDC42-binding protein kinase beta; CDC42BP-beta; DMPK-like beta; Myotonic dystrophy kinase-related CDC42-binding kinase beta; MRCK beta; Myotonic dystrophy protein kinase-like beta
 Protein Family    Serine/threonine-protein kinase
 UniProt Gene Name    CDC42BPB [Similar Products]
 UniProt Synonym Gene Names    KIAA1124; CDC42BP-beta; MRCK beta; Myotonic dystrophy protein kinase-like beta [Similar Products]
 UniProt Entry Name    MRCKB_HUMAN
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 NCBI Summary for CDC42BPB    This gene encodes a member of the serine/threonine protein kinase family. The encoded protein contains a Cdc42/Rac-binding p21 binding domain resembling that of PAK kinase. The kinase domain of this protein is most closely related to that of myotonic dystrophy kinase-related ROK. Studies of the similar gene in rat suggested that this kinase may act as a downstream effector of Cdc42 in cytoskeletal reorganization. [provided by RefSeq, Jul 2008]
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 UniProt Comments for CDC42BPB    MRCKB: Serine/threonine-protein kinase which is an important downstream effector of CDC42 and plays a role in the regulation of cytoskeleton reorganization and cell migration. Regulates actin cytoskeletal reorganization via phosphorylation of PPP1R12C and MYL9/MLC2. In concert with MYO18A and LURAP1, is involved in modulating lamellar actomyosin retrograde flow that is crucial to cell protrusion and migration. Phosphorylates PPP1R12A. Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. DMPK subfamily.

Protein type: Protein kinase, AGC; Kinase, protein; Protein kinase, Ser/Thr (non-receptor); EC 2.7.11.1; AGC group; DMPK family; GEK subfamily

Chromosomal Location of Human Ortholog: 14q32.3

Cellular Component: cytoskeleton; leading edge; cytoplasm; plasma membrane; actomyosin; intercellular junction

Molecular Function: protein serine/threonine kinase activity; Rho GTPase binding; magnesium ion binding; ATP binding; protein kinase activity

Biological Process: cell migration; regulation of catalytic activity; actomyosin structure organization and biogenesis; actin cytoskeleton reorganization; establishment and/or maintenance of cell polarity; cytoskeleton organization and biogenesis; signal transduction; protein amino acid phosphorylation
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 Research Articles on CDC42BPB    1. these results provide further validation for MRCK involvement in regulation of cancer cell invasion.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Diseases associated with CDC42BPB elisa kitOrgans/Tissues associated with CDC42BPB elisa kit
 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >5 publications with CDC42BPB and Neoplasms
 Inflammation Antibodies  >1 publications with CDC42BPB and Inflammation
 Prostatic Neoplasms Antibodies  >1 publications with CDC42BPB and Prostatic Neoplasms
 Breast Neoplasms Antibodies  >1 publications with CDC42BPB and Breast Neoplasms
 Prostatic Diseases Antibodies  >1 publications with CDC42BPB and Prostatic Diseases
 Organ/Tissue Name  Pubmed Publications
 Heart Antibodies  >1 publications with CDC42BPB and Heart
 Blood Antibodies  >1 publications with CDC42BPB and Blood
 Bone Antibodies  >1 publications with CDC42BPB and Bone
 Nerve Antibodies  >1 publications with CDC42BPB and Nerve
 Muscle Antibodies  >1 publications with CDC42BPB and Muscle
 Prostate Antibodies  >1 publications with CDC42BPB and Prostate
 Eye Antibodies  >1 publications with CDC42BPB and Eye
 Brain Antibodies  >1 publications with CDC42BPB and Brain
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