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CLDN3 elisa kit :: Human CLDN3 ELISA Kit

Scan QR to view Datasheet Catalog #    MBS2505784
Typical Testing Data/Standard Curve (for reference only)
Unit / Price
48-Strip-Wells  /  $410 +1 FREE 8GB USB
96-Strip-Wells  /  $490 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,040 +2 FREE 8GB USB
10x96-Strip-Wells  /  $3,590 +4 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

CLDN3, ELISA Kit

★Popular Item★
 Also Known As   

Human CLDN3 (Claudin 3) ELISA Kit

 Product Gene Name   

CLDN3 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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  Sample Manual Insert    Download PDF Manual View PDF Manual
 Request for Current Manual Insert    Request Current Manual
 MBS2505784 COA    COA PDF
 OMIM    602910
 3D Structure    ModBase 3D Structure for O15551
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 Species Reactivity    Human
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 Specificity    This kit recognizes natural and some recombinant Human CLDN3. No significant crossreactivity or interference between Human CLDN3 and analogues was observed.
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 Samples    Serum, plasma and other biological fluids
 Assay Type    Quantitative Sandwich
 Detection Range    0.31-20 ng/mL
 Sensitivity    0.19 ng/mL
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 Preparation and Storage    Store at 4 degree C.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of CLDN3 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for CLDN3 purchase    MBS2505784 is a ready-to-use microwell, strip plate Quantitative Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the CLDN3, ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range of 0.31-20 ng/mL in biological research samples containing CLDN3, with an estimated sensitivity of 0.19 ng/mL. The ELISA analytical biochemical technique of the MBS2505784 kit is based on CLDN3 antibody-CLDN3 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect CLDN3 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, CLDN3. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions such as Serum, plasma and other biological fluids. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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Related Product Information for CLDN3 elisa kit

   Intended Uses: This ELISA kit can be applied to the in vitro quantitative determination of Human CLDN3 concentrations in serum, plasma and other biological fluids.

Principle of the Assay: This ELISA kit uses Sandwich-ELISA as the method. The micro ELISA plate provided in this kit has been precoated with an antibody specific to Human CLDN3. Standards or samples are added to appropriate micro ELISA plate wells and combined with the specific antibody. Then a biotinylated detection antibodies specific for Human CLDN3 and Avidin-Horseradish Peroxidase (HRP) conjugate are added to each micro plate well successively and incubated. After incubation, free components are washed away. Then the Substrate Reagent is added to each well, only those wells that contain Human CLDN3, biotinylated detection antibody and Avidin-HRP conjugate will appear blue in color. The enzyme-substrate reaction will be terminated by adding Stop Solution and appears yellow in color. The optical density (OD) can be measured with spectrophotometry at a wavelength of 450 nm +/- 2 nm. The OD value is proportional to the concentration of Human CLDN3. The concentration of Human CLDN3 in samples can be calculated by comparing the OD of the samples with the standard curve.
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 Typical Testing Data/Standard Curve (for reference only) of CLDN3 elisa kit    CLDN3 elisa kit Typical Testing Data/Standard Curve (for reference only) image
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Sample Manual Insert of MBS2505784. Click to request current manual
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NCBI/Uniprot data below describe general gene information for CLDN3. It may not necessarily be applicable to this product.
 NCBI GI #    4502875
 NCBI GeneID    1365
 NCBI Accession #    NP_001297.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001306.3 [Other Products]
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 UniProt Primary Accession #    O15551 [Other Products]
 UniProt Related Accession #    O15551 [Other Products]
 Molecular Weight    23,319 Da
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 NCBI Official Full Name    claudin-3
 NCBI Official Synonym Full Names    claudin 3
 NCBI Official Symbol    CLDN3 [Similar Products]
 NCBI Official Synonym Symbols   
RVP1; HRVP1; C7orf1; CPE-R2; CPETR2
[Similar Products]
 NCBI Protein Information    claudin-3; CPE-R 2; CPE-receptor 2; Clostridium perfringens enterotoxin receptor 2; ventral prostate.1 protein homolog; ventral prostate.1-like protein
 UniProt Protein Name    Claudin-3
 UniProt Synonym Protein Names   
Clostridium perfringens enterotoxin receptor 2; CPE-R 2; CPE-receptor 2; Rat ventral prostate.1 protein homolog; hRVP1
 Protein Family    Claudin
 UniProt Gene Name    CLDN3 [Similar Products]
 UniProt Synonym Gene Names    C7orf1; CPETR2; CPE-R 2; CPE-receptor 2; hRVP1 [Similar Products]
 UniProt Entry Name    CLD3_HUMAN
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 NCBI Summary for CLDN3    Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. The protein encoded by this intronless gene, a member of the claudin family, is an integral membrane protein and a component of tight junction strands. It is also a low-affinity receptor for Clostridium perfringens enterotoxin, and shares aa sequence similarity with a putative apoptosis-related protein found in rat. [provided by RefSeq, Jul 2008]
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 UniProt Comments for CLDN3    Claudin-3: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium- independent cell-adhesion activity. CLDN3 is located in the Williams-Beuren syndrome (WBS) critical region. WBS results from a hemizygous deletion of several genes on chromosome 7q11.23, thought to arise as a consequence of unequal crossing over between highly homologous low-copy repeat sequences flanking the deleted region. Belongs to the claudin family.

Protein type: Membrane protein, integral; Membrane protein, multi-pass; Cytoskeletal

Chromosomal Location of Human Ortholog: 7q11.23

Cellular Component: tight junction; integral to plasma membrane; integral to membrane; lateral plasma membrane

Molecular Function: identical protein binding; transmembrane receptor activity; structural molecule activity

Biological Process: response to hypoxia; signal transduction; calcium-independent cell-cell adhesion
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 Research Articles on CLDN3    1. Claudin 3 was expressed in all non-goblet columnar lined oesophagus, Barrett's oesophagus, high grade dysplasia and adenocarcinoma.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with CLDN3 elisa kitPathways associated with CLDN3 elisa kit
 Reference Product  PubMed Publications
 CLDN4 elisa kit  >121 publications with CLDN3 and CLDN4
 CLDN1 elisa kit  >99 publications with CLDN3 and CLDN1
 CLDN5 elisa kit  >49 publications with CLDN3 and CLDN5
 OCLN elisa kit  >48 publications with CLDN3 and OCLN
 TJP1 elisa kit  >34 publications with CLDN3 and TJP1
 CLDN7 elisa kit  >33 publications with CLDN3 and CLDN7
 TJP2 elisa kit  >2 publications with CLDN3 and TJP2
 CLDN16 elisa kit  >1 publications with CLDN3 and CLDN16
 TJP3 elisa kit  >1 publications with CLDN3 and TJP3
 Products by Pathway  Pathway Diagram
 Cell Adhesion Molecules (CAMs) Pathway antibodies  Cell Adhesion Molecules (CAMs) Pathway Diagram
 Cell Adhesion Molecules (CAMs) Pathway antibodies  Cell Adhesion Molecules (CAMs) Pathway Diagram
 Cell Junction Organization Pathway antibodies  Cell Junction Organization Pathway Diagram
 Cell-Cell Communication Pathway antibodies  Cell-Cell Communication Pathway Diagram
 Cell-cell Junction Organization Pathway antibodies  Cell-cell Junction Organization Pathway Diagram
 Hepatitis C Pathway antibodies  Hepatitis C Pathway Diagram
 Hepatitis C Pathway antibodies  Hepatitis C Pathway Diagram
 Leukocyte Transendothelial Migration Pathway antibodies  Leukocyte Transendothelial Migration Pathway Diagram
 Leukocyte Transendothelial Migration Pathway antibodies  Leukocyte Transendothelial Migration Pathway Diagram
 Tight Junction Pathway antibodies  Tight Junction Pathway Diagram
Diseases associated with CLDN3 elisa kitOrgans/Tissues associated with CLDN3 elisa kit
 Disease Name  Pubmed Publications
 Carcinoma Antibodies  >66 publications with CLDN3 and Carcinoma
 Adenocarcinoma Antibodies  >40 publications with CLDN3 and Adenocarcinoma
 Ovarian Neoplasms Antibodies  >36 publications with CLDN3 and Ovarian Neoplasms
 Breast Neoplasms Antibodies  >20 publications with CLDN3 and Breast Neoplasms
 Inflammation Antibodies  >16 publications with CLDN3 and Inflammation
 Necrosis Antibodies  >15 publications with CLDN3 and Necrosis
 Stomach Neoplasms Antibodies  >13 publications with CLDN3 and Stomach Neoplasms
 Nervous System Diseases Antibodies  >12 publications with CLDN3 and Nervous System Diseases
 Neoplasm Metastasis Antibodies  >12 publications with CLDN3 and Neoplasm Metastasis
 Neoplasm Invasiveness Antibodies  >11 publications with CLDN3 and Neoplasm Invasiveness
 Organ/Tissue Name  Pubmed Publications
 Intestine Antibodies  >43 publications with CLDN3 and Intestine
 Liver Antibodies  >23 publications with CLDN3 and Liver
 Lung Antibodies  >18 publications with CLDN3 and Lung
 Kidney Antibodies  >17 publications with CLDN3 and Kidney
 Stomach Antibodies  >17 publications with CLDN3 and Stomach
 Prostate Antibodies  >12 publications with CLDN3 and Prostate
 Ovary Antibodies  >12 publications with CLDN3 and Ovary
 Testis Antibodies  >11 publications with CLDN3 and Testis
 Embryonic Tissue Antibodies  >8 publications with CLDN3 and Embryonic Tissue
 Eye Antibodies  >7 publications with CLDN3 and Eye
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