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CTPS2 elisa kit :: Human CTP synthase 2, CTPS2 ELISA Kit

Scan QR to view Datasheet Catalog #    MBS2602678
Typical Testing Data/Standard Curve (for reference only)
Unit / Price
48-Strip-Wells  /  $275 +1 FREE 8GB USB
96-Strip-Wells  /  $420 +1 FREE 8GB USB
5x96-Strip-Wells  /  $1,615 +2 FREE 8GB USB
10x96-Strip-Wells  /  $2,880 +3 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

CTP synthase 2, CTPS2, ELISA Kit

★Popular Item★
 Also Known As   

Human CTP synthase 2, CTPS2 ELISA Kit

 Product Gene Name   

CTPS2 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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  Sample Manual Insert    Download PDF Manual View PDF Manual
 Request for Current Manual Insert    Request Current Manual
 OMIM    300380
 3D Structure    ModBase 3D Structure for Q9NRF8
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 Species Reactivity    Human
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 Specificity    No cross-reaction with other factors.
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 Samples    Human serum, plasma or Cell Culture Supernatant and organizations in the natural and recombinant CTPS2 concentration
 Assay Type    Sandwich
 Detection Range    20 ng/ml-0.312 ng/ml
 Sensitivity    0.06 ng/ml.
 Intra-assay Precision    <= 8%
 Inter-assay Precision    <= 12%
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 Preparation and Storage    Store all reagents at 2-8 degree C.
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of CTPS2 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for CTPS2 purchase    MBS2602678 is a ready-to-use microwell, strip plate Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the CTP synthase 2, CTPS2, ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range of 20 ng/ml-0.312 ng/ml in biological research samples containing CTPS2, with an estimated sensitivity of 0.06 ng/ml. The ELISA analytical biochemical technique of the MBS2602678 kit is based on CTPS2 antibody-CTPS2 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect CTPS2 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, CTPS2. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions such as Human serum, plasma or Cell Culture Supernatant and organizations in the natural and recombinant CTPS2 concentration. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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Product Description specifically for CTPS2 elisa kit

   Priciple of the assay: This experiment use double-sandwich elisa technique and the ELISA Kit provided is typical. The pre-coated antibody is human CTPS2 monoclonal antibody and the detecting antibody is polyclonal antibody with biotin labeled. Samples and biotin labeling antibody are added into ELISA plate wells and washed out with PBS or TBS. Then Avidin-peroxidase conjugates are added to ELISA wells in order; Use TMB substrate for coloring after reactant thoroughly washed out by PBS or TBS. TMB turns into blue in peroxidase catalytic and finally turns into yellow under the action of acid. The color depth and the testing factors in samples are positively correlated.
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 Typical Testing Data/Standard Curve (for reference only) of CTPS2 elisa kit    CTPS2 elisa kit Typical Testing Data/Standard Curve (for reference only) image
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Sample Manual Insert of MBS2602678. Click to request current manual
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NCBI/Uniprot data below describe general gene information for CTPS2. It may not necessarily be applicable to this product.
 NCBI GI #    221316689
 NCBI GeneID    56474
 NCBI Accession #    NP_001137474.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001144002.1 [Other Products]
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 UniProt Primary Accession #    Q9NRF8 [Other Products]
 UniProt Secondary Accession #    Q9BRI0; Q9H809; Q9H8K9; B3KWM2 [Other Products]
 UniProt Related Accession #    Q9NRF8 [Other Products]
 Molecular Weight    65,678 Da
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 NCBI Official Full Name    CTP synthase 2
 NCBI Official Synonym Full Names    CTP synthase 2
 NCBI Official Symbol    CTPS2 [Similar Products]
 NCBI Protein Information    CTP synthase 2; CTP synthase II; UTP-ammonia ligase 2; CTP synthetase type 2; cytidine 5'-triphosphate synthetase 2
 UniProt Protein Name    CTP synthase 2
 UniProt Synonym Protein Names   
CTP synthetase 2; UTP--ammonia ligase 2
 Protein Family    CTP synthase
 UniProt Gene Name    CTPS2 [Similar Products]
 UniProt Entry Name    PYRG2_HUMAN
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 NCBI Summary for CTPS2    The protein encoded by this gene catalyzes the formation of CTP from UTP with the concomitant deamination of glutamine to glutamate. This protein is the rate-limiting enzyme in the synthesis of cytosine nucleotides, which play an important role in various metabolic processes and provide the precursors necessary for the synthesis of RNA and DNA. Cancer cells that exhibit increased cell proliferation also exhibit an increased activity of this encoded protein. Thus, this protein is an attractive target for selective chemotherapy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]
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 UniProt Comments for CTPS2    CTPS2: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Constitutes the rate-limiting enzyme in the synthesis of cytosine nucleotides. Belongs to the CTP synthase family.

Protein type: Nucleotide Metabolism - pyrimidine; EC 6.3.4.2; Ligase

Chromosomal Location of Human Ortholog: Xp22

Cellular Component: mitochondrion; cytosol

Molecular Function: CTP synthase activity; ATP binding

Biological Process: nucleobase, nucleoside and nucleotide metabolic process; nucleobase, nucleoside and nucleotide interconversion; pyrimidine nucleotide metabolic process; glutamine metabolic process
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 Research Articles on CTPS2    1. CTPS2 was identified by genome-wide gene expression analyses as correlated with cellular sensitivity to cisplatin and carboplatin.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with CTPS2 elisa kitDiseases associated with CTPS2 elisa kit
 Products by Pathway  Pathway Diagram
 Metabolism Pathway antibodies  Metabolism Pathway Diagram
 Metabolism Of Nucleotides Pathway antibodies  Metabolism Of Nucleotides Pathway Diagram
 Pyrimidine Metabolism Pathway antibodies  Pyrimidine Metabolism Pathway Diagram
 Pyrimidine Metabolism Pathway antibodies  Pyrimidine Metabolism Pathway Diagram
 Pyrimidine Ribonucleotide Biosynthesis, UMP => UDP/UTP,CDP/CTP Pathway antibodies  Pyrimidine Ribonucleotide Biosynthesis, UMP => UDP/UTP,CDP/CTP Pathway Diagram
 Pyrimidine Ribonucleotide Biosynthesis, UMP => UDP/UTP,CDP/CTP Pathway antibodies  Pyrimidine Ribonucleotide Biosynthesis, UMP => UDP/UTP,CDP/CTP Pathway Diagram
 Synthesis And Interconversion Of Nucleotide Di- And Triphosphates Pathway antibodies  Synthesis And Interconversion Of Nucleotide Di- And Triphosphates Pathway Diagram
 Pyrimidine Ribonucleotides De Novo Biosynthesis Pathway antibodies  Pyrimidine Ribonucleotides De Novo Biosynthesis Pathway Diagram
 Pyrimidine Ribonucleotides Interconversion Pathway antibodies  Pyrimidine Ribonucleotides Interconversion Pathway Diagram
 Pyrimidine Ribonucleotides Interconversion Pathway antibodies  Pyrimidine Ribonucleotides Interconversion Pathway Diagram
 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >1 publications with CTPS2 and Neoplasms
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