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CDH6 elisa kit :: Human Cadherin-6 ELISA Kit

Scan QR to view Datasheet Catalog #    MBS762016
Typical Standard Curve/Testing Data
Unit / Price
48-Strip-Wells  /  $295 +1 FREE 8GB USB
96-Strip-Wells  /  $390 +1 FREE 8GB USB
5x96-Strip-Wells  /  $1,615 +2 FREE 8GB USB
10x96-Strip-Wells  /  $3,015 +3 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Cadherin-6 (CDH6), ELISA Kit

 Also Known As   

Human Cadherin-6 ELISA Kit

 Product Synonym Names    CDH6/K-Cadherin/cadherin 6; type 2; K-cadherin (fetal kidney)/cadherin; fetal kidney/cadherin-6/KCAD/K-cadherin/K-cadherin (fetal kidney)
 Product Gene Name   

CDH6 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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  Sample Manual Insert    Download PDF Manual View PDF Manual
 Request for Current Manual Insert    Request Current Manual
 MBS762016 COA    COA PDF
 OMIM    603007
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 Species Reactivity    Human
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 Specificity    This assay has high sensitivity and excellent specificity for detection of CDH6. No significant cross-reactivity or interference between CDH6 and analogues was observed. Note: Limited by current skills and knowledge, it is difficult for us to complete the crossreactivity detection between CDH6 and all the analogues, therefore, cross reaction may still exist.
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 Samples    Serum, plasma, tissue homogenates and other biological fluids
 Assay Type    Quantitative Sandwich
 Detection Range    0.312-20ng/ml
 Sensitivity    <0.188ng/ml
 Intra-assay Precision    Intra-assay Precision (Precision within an assay): 3 samples with low, middle and high level CDH6 were tested 20 times on one plate, respectively. Intra-Assay: CV<8%
 Inter-assay Precision    Inter-assay Precision (Precision between assays): 3 samples with low, middle and high level CDH6 were tested on 3 different plates, 8 replicates in each plate. CV (%) = SD/meanX100. Inter-Assay: CV<10%
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 Preparation and Storage    Store at 4 degree C if kit is to be used within 1 week. Stable for 6 months (if micro ELISA Plate, Lyophilized Standard and Concentrated Biotinylated Detection Protein stored at-20 degree C. Other components at 2-8 degree C). Stable for 12 months (if the entire kit is stored at-20 degree C).
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Product Note    Our ELISA assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of CDH6 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for CDH6 purchase    MBS762016 is a ready-to-use microwell, strip plate Quantitative Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Cadherin-6 (CDH6) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range of 0.312-20ng/ml in biological research samples containing CDH6, with an estimated sensitivity of <0.188ng/ml. The ELISA analytical biochemical technique of the MBS762016 kit is based on CDH6 antibody-CDH6 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect CDH6 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, CDH6. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions such as Serum, plasma, tissue homogenates and other biological fluids. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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Product Description specifically for CDH6 elisa kit

   Principle of the Assay: This kit was based on sandwich enzyme-linked immune-sorbent assay technology. Anti- CDH6 antibody was pre-coated onto 96-well plates. And the biotin conjugated anti- CDH6 antibody was used as detection antibodies. The standards, test samples and biotin conjugated detection antibody were added to the wells subsequently, and washed with wash buffer. HRPStreptavidin was added and unbound conjugates were washed away with wash buffer. TMB substrates were used to visualize HRP enzymatic reaction. TMB was catalyzed by HRP to produce a blue color product that changed into yellow after adding acidic stop solution. The density of yellow is proportional to the CDH6 amount of sample captured in plate. Read the O.D. absorbance at 450nm in a microplate reader, and then the concentration of CDH6 can be calculated.
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 Typical Standard Curve/Testing Data of CDH6 elisa kit    CDH6 elisa kit Typical Standard Curve/Testing Data image
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Sample Manual Insert of MBS762016. Click to request current manual
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NCBI/Uniprot data below describe general gene information for CDH6. It may not necessarily be applicable to this product.
 NCBI GI #    4826673
 NCBI GeneID    1004
 NCBI Accession #    NP_004923.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_004932.3 [Other Products]
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 UniProt Secondary Accession #    Q9BWS0; A8K5H5 [Other Products]
 UniProt Related Accession #    P55285 [Other Products]
 Molecular Weight    73,864 Da
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 NCBI Official Full Name    cadherin-6 preproprotein
 NCBI Official Synonym Full Names    cadherin 6
 NCBI Official Symbol    CDH6 [Similar Products]
 NCBI Official Synonym Symbols   
CAD6; KCAD
[Similar Products]
 NCBI Protein Information    cadherin-6
 UniProt Protein Name    Cadherin-6
 UniProt Synonym Protein Names   
Kidney cadherin; K-cadherin
 Protein Family    Cadherin
 UniProt Gene Name    CDH6 [Similar Products]
 UniProt Synonym Gene Names    K-cadherin [Similar Products]
 UniProt Entry Name    CADH6_HUMAN
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 NCBI Summary for CDH6    This gene encodes a member of the cadherin superfamily. Cadherins are membrane glycoproteins that mediate homophilic cell-cell adhesion and play critical roles in cell differentiation and morphogenesis. The encoded protein is a type II cadherin and may play a role in kidney development as well as endometrium and placenta formation. Decreased expression of this gene may be associated with tumor growth and metastasis. [provided by RefSeq, May 2011]
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 UniProt Comments for CDH6    CDH6: Cadherins are calcium dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. Highly expressed in brain, cerebellum, and kidney. Lung, pancreas, and gastric mucosa show a weak expression. Also expressed in certain liver and kidney carcinomas. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral; Cell adhesion

Chromosomal Location of Human Ortholog: 5p13.3

Cellular Component: integral to membrane; plasma membrane

Molecular Function: calcium ion binding

Biological Process: cell adhesion; homophilic cell adhesion; intercellular junction assembly and maintenance; Notch signaling pathway
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 Research Articles on CDH6    1. CDH6 is under the control of the transcription factor RUNX2, which we previously described as a crucial mediator of the Id1 pro-invasive function in thyroid tumor cells.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with CDH6 elisa kitPathways associated with CDH6 elisa kit
 Reference Product  PubMed Publications
 CDH4 elisa kit  >8 publications with CDH6 and CDH4
 CDH7 elisa kit  >6 publications with CDH6 and CDH7
 CDH9 elisa kit  >3 publications with CDH6 and CDH9
 CDH13 elisa kit  >2 publications with CDH6 and CDH13
 CDH10 elisa kit  >2 publications with CDH6 and CDH10
 CDH15 elisa kit  >1 publications with CDH6 and CDH15
 CDH18 elisa kit  >1 publications with CDH6 and CDH18
 Products by Pathway  Pathway Diagram
 Adherens Junctions Interactions Pathway antibodies  Adherens Junctions Interactions Pathway Diagram
 Cell Junction Organization Pathway antibodies  Cell Junction Organization Pathway Diagram
 Cell-Cell Communication Pathway antibodies  Cell-Cell Communication Pathway Diagram
 Cell-cell Junction Organization Pathway antibodies  Cell-cell Junction Organization Pathway Diagram
 Neural Crest Differentiation Pathway antibodies  Neural Crest Differentiation Pathway Diagram
Diseases associated with CDH6 elisa kitOrgans/Tissues associated with CDH6 elisa kit
 Disease Name  Pubmed Publications
 Adenocarcinoma Antibodies  >2 publications with CDH6 and Adenocarcinoma
 Inflammation Antibodies  >2 publications with CDH6 and Inflammation
 Neoplasm Metastasis Antibodies  >2 publications with CDH6 and Neoplasm Metastasis
 Nervous System Malformations Antibodies  >2 publications with CDH6 and Nervous System Malformations
 Learning Disorders Antibodies  >2 publications with CDH6 and Learning Disorders
 Lung Neoplasms Antibodies  >2 publications with CDH6 and Lung Neoplasms
 Liver Neoplasms Antibodies  >2 publications with CDH6 and Liver Neoplasms
 Abnormalities, Multiple Antibodies  >2 publications with CDH6 and Abnormalities, Multiple
 Embryo Loss Antibodies  >1 publications with CDH6 and Embryo Loss
 Cell Transformation, Neoplastic Antibodies  >1 publications with CDH6 and Cell Transformation, Neoplastic
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >16 publications with CDH6 and Brain
 Eye Antibodies  >5 publications with CDH6 and Eye
 Embryonic Tissue Antibodies  >3 publications with CDH6 and Embryonic Tissue
 Skin Antibodies  >2 publications with CDH6 and Skin
 Prostate Antibodies  >2 publications with CDH6 and Prostate
 Lung Antibodies  >2 publications with CDH6 and Lung
 Kidney Antibodies  >2 publications with CDH6 and Kidney
 Muscle Antibodies  >1 publications with CDH6 and Muscle
 Testis Antibodies  >1 publications with CDH6 and Testis
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