NP_001272985.1
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NCBI GenBank Nucleotide #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
31,380 Da
NCBI Official Full Name
calponin-3 isoform 3
NCBI Official Synonym Full Names
calponin 3, acidic
NCBI Protein Information
calponin-3; calponin, acidic isoform; dJ639P13.2.2 (acidic calponin 3)
UniProt Protein Name
Calponin-3
UniProt Synonym Protein Names
Calponin, acidic isoform
UniProt Entry Name
CNN3_HUMAN
NCBI Summary for CNN3
This gene encodes a protein with a markedly acidic C terminus; the basic N-terminus is highly homologous to the N-terminus of a related gene, CNN1. Members of the CNN gene family all contain similar tandemly repeated motifs. This encoded protein is associated with the cytoskeleton but is not involved in contraction. [provided by RefSeq, Jul 2008]
UniProt Comments for CNN3
calponin 3: Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin, troponin C and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity. Belongs to the calponin family.
Protein type: Motility/polarity/chemotaxis; Cytoskeletal
Chromosomal Location of Human Ortholog: 1p22-p21
Cellular Component: focal adhesion; cytoplasm; actin cytoskeleton
Molecular Function: calmodulin binding; actin binding
Biological Process: epithelial cell differentiation; actomyosin structure organization and biogenesis
Research Articles on CNN3
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Products associated with CNN3 elisa kit
Diseases associated with CNN3 elisa kit
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