Antibody Protein ELISA Kit from MyBioSource header Telephone 1.858.633.0165          
1.855.MyBioSource
Fax 1.858.633.0166    Email sales@mybiosource.com 
tel/fax
menu1 Home Products Ordering Company Help menu7
bottom
   MyBioSource rightarrow ELISA Kit rightarrow COL17A1 rightarrow Human COL17A1  rightarrow LOG IN  rightarrow MY ACCOUNT  rightarrow CART CONTENTS  rightarrow CHECKOUT 
horiz bar
MyBioSource Menu separator
separator
ELISA Kit ELISA Kit
CLIA Kit CLIA Kit
PCR Kit PCR Kit
Monoclonal Antibody Monoclonal Antibody
Polyclonal Antibody Polyclonal Antibody
Secondary Antibody Secondary Antibody
Antigen Antigen
Biochemical Biochemical
cDNA Clone cDNA Clone
siRNA siRNA
Peptide Peptide
Recombinant/Purified Protein Rec./Purified Protein

Custom ELISA Kit Custom ELISA Kit
Custom Protein Custom Protein
Custom Antibody Custom Antibody
Antibody Matched Pairs Antibody Matched Pairs
Antibody & Corresponding Blocking Peptide Pairs Antibody Peptide Pairs
Phospho-Specific Antibodies Phospho Antibodies
Products by Disease Products by Disease
Products by Pathway Products by Pathway
Products by Tissue Products by Tissue

arrow Advanced Search
arrow Submit Technical Q&A
arrow International Distributors
arrow Contact Us
separator
Our Best Sellers moreseparator
separator
 • GK cDNA Clone
 • GARNL1 Antibody
 • interleukin 1 family, member 9 (IL1F9) ELISA Kit
 • I-Ek (public; Ia.m7) Antibody
 • ZAP70 Antibody
 • Inhibin-Alpha A Chain (INHA) Recombinant Protein
 • Matrix Metalloproteinase 2 (MMP2) ELISA Kit
 • HIV-1 p24 Antibody
 • Granzyme B (GZMB) Antibody
 • Cryptosporidium parvum Antibody
 • HRP Conjugated Goat Anti-human IgA Secondary Antibody
 • RAB4B Antibody
 • Claudin-18 (CLDN18) Recombinant Protein
 • Osteocalcin ELISA Kit
 downarrow more ...
separator
separator
DatasheetFull DatasheetPrinter Friendly DatasheetPrint This DatasheetAdd to Compare ListHave Questions? Ask UsRequest for a Quotation today

COL17A1 elisa kit :: Human Collagen alpha-1(XVII) chain ELISA Kit

Scan QR to view Datasheet Catalog #    MBS289893
Typical Testing Data/Standard Curve (for reference only)
Unit / Price
48-Strip-Wells  /  $380 +1 FREE 8GB USB
96-Strip-Wells  /  $500 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,170 +2 FREE 8GB USB
10x96-Strip-Wells  /  $3,840 +4 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Collagen alpha-1(XVII) chain (COL17A1), ELISA Kit

★Popular Item★
 Also Known As   

Human Collagen alpha-1(XVII) chain ELISA Kit

 Product Synonym Names    Collagen alpha-1(XVII) chain; 180 kDa bullous pemphigoid antigen 2; Bullous pemphigoid antigen 2; COL17A1; BP180; BPAG2
 Product Gene Name   

COL17A1 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
Table BarTOPTable Bar
  Sample Manual Insert    Download PDF Manual View PDF Manual
 Request for Current Manual Insert    Request Current Manual
 MBS289893 Testing Data    Testing Data PDF
 OMIM    113811
 3D Structure    ModBase 3D Structure for Q9UMD9
Section Bar
 Species Reactivity    Human
Section Bar
Section Bar
 Assay Type    Sandwich
 Detection Range    0.156-10 ng/ml
 Sensitivity    0.089 ng/mL
 Intra-Assay CV    <=5.1%
 Inter-Assay CV    <=7.4%
 Recovery    88%
Section Bar
 Preparation and Storage    For long term storage, please store the entire kit at -20 degree C.
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of COL17A1 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for COL17A1 purchase    MBS289893 is a ready-to-use microwell, strip plate Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Collagen alpha-1(XVII) chain (COL17A1) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range of 0.156-10 ng/ml in biological research samples containing COL17A1, with an estimated sensitivity of 0.089 ng/mL. The ELISA analytical biochemical technique of the MBS289893 kit is based on COL17A1 antibody-COL17A1 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect COL17A1 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, COL17A1. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
Table BarTOPTable Bar
 

Related Product Information for COL17A1 elisa kit

   Intended Uses: This immunoassay kit allows for the in vitro quantitative determination of target antigen concentrations in serum, plasma, tissue homogenates, cell culture supernates or other biological fluids.

Principle of the Assay: The microtiter plate provided in this kit has been pre-coated with an antibody specific to target antigen. Standards or samples are then added to the appropriate microtiter plate wells with a biotin-conjugated antibody preparation specific for target antigen and then avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. Then a TMB substrate solution is added to each well. Only those wells that contain target antigen, biotin-conjugated antibody and enzyme-conjugated Avidin will exhibit a change in color. The enzyme-substrate reaction is terminated by the addition of a sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450 nm +/- 2 nm. The concentration of target antigen in the samples is then determined by comparing the O.D. of the samples to the standard curve.
Section Bar
 Typical Testing Data/Standard Curve (for reference only) of COL17A1 elisa kit    COL17A1 elisa kit Typical Testing Data/Standard Curve (for reference only) image
Table BarTOPTable Bar
Sample Manual Insert of MBS289893. Click to request current manual
Table BarTOPTable Bar
NCBI/Uniprot data below describe general gene information for COL17A1. It may not necessarily be applicable to this product.
 NCBI GI #    119829187
 NCBI GeneID    1308
 NCBI Accession #    NP_000485.3 [Other Products]
 NCBI GenBank Nucleotide #    NM_000494.3 [Other Products]
Section Bar
 UniProt Primary Accession #    Q9UMD9 [Other Products]
 UniProt Secondary Accession #    Q02802; Q5JV36; Q99018; Q9NQK9; Q9UC14 [Other Products]
 UniProt Related Accession #    Q9UMD9 [Other Products]
 Molecular Weight    142,344 Da
Table BarTOPTable Bar
 NCBI Official Full Name    collagen alpha-1(XVII) chain
 NCBI Official Synonym Full Names    collagen type XVII alpha 1
 NCBI Official Symbol    COL17A1 [Similar Products]
 NCBI Official Synonym Symbols   
ERED; BP180; BPA-2; BPAG2; LAD-1; BA16H23.2
[Similar Products]
 NCBI Protein Information    collagen alpha-1(XVII) chain
 UniProt Protein Name    Collagen alpha-1(XVII) chain
 UniProt Synonym Protein Names   
180 kDa bullous pemphigoid antigen 2; Bullous pemphigoid antigen 2
 UniProt Gene Name    COL17A1 [Similar Products]
 UniProt Synonym Gene Names    BP180; BPAG2; LAD-1; 97 kDa LAD antigen; 97-LAD; LABD97 [Similar Products]
 UniProt Entry Name    COHA1_HUMAN
Section Bar
 NCBI Summary for COL17A1    This gene encodes the alpha chain of type XVII collagen. Unlike most collagens, collagen XVII is a transmembrane protein. Collagen XVII is a structural component of hemidesmosomes, multiprotein complexes at the dermal-epidermal basement membrane zone that mediate adhesion of keratinocytes to the underlying membrane. Mutations in this gene are associated with both generalized atrophic benign and junctional epidermolysis bullosa. Two homotrimeric forms of type XVII collagen exist. The full length form is the transmembrane protein. A soluble form, referred to as either ectodomain or LAD-1, is generated by proteolytic processing of the full length form. [provided by RefSeq, Jul 2008]
Section Bar
 UniProt Comments for COL17A1    COL17A1: May play a role in the integrity of hemidesmosome and the attachment of basal keratinocytes to the underlying basement membrane. Defects in COL17A1 are a cause of generalized atrophic benign epidermolysis bullosa (GABEB). GABEB is a non- lethal, adult form of junctional epidermolysis bullosa characterized by life-long blistering of the skin, associated with hair and tooth abnormalities. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral; Motility/polarity/chemotaxis; Extracellular matrix

Chromosomal Location of Human Ortholog: 10q24.3

Cellular Component: basement membrane; collagen; endoplasmic reticulum lumen; extracellular region; hemidesmosome; integral to plasma membrane; intercellular junction; plasma membrane

Molecular Function: protein binding

Biological Process: cell-matrix adhesion; collagen catabolic process; epidermis development; extracellular matrix disassembly; extracellular matrix organization and biogenesis; hemidesmosome assembly; regulation of immune response

Disease: Epidermolysis Bullosa, Junctional, Non-herlitz Type; Epithelial Recurrent Erosion Dystrophy
Table BarTOPTable Bar
 Research Articles on COL17A1    1. Our findings implicate presumed gain-of-function COL17A1 mutations causing dominantly inherited ERED and improve understanding of the underlying pathology.
Table BarTOPTable Bar
 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Table BarTOPTable Bar
Products associated with COL17A1 elisa kitPathways associated with COL17A1 elisa kit
 Reference Product  PubMed Publications
 DST elisa kit  >17 publications with COL17A1 and DST
 LAMB3 elisa kit  >16 publications with COL17A1 and LAMB3
 LAMC2 elisa kit  >10 publications with COL17A1 and LAMC2
 LAMA3 elisa kit  >8 publications with COL17A1 and LAMA3
 ITGB4 elisa kit  >7 publications with COL17A1 and ITGB4
 ITGA6 elisa kit  >1 publications with COL17A1 and ITGA6
 PLEC elisa kit  >1 publications with COL17A1 and PLEC
 Products by Pathway  Pathway Diagram
 Alpha6-Beta4 Integrin Signaling Pathway antibodies  Alpha6-Beta4 Integrin Signaling Pathway Diagram
 Cell Junction Organization Pathway antibodies  Cell Junction Organization Pathway Diagram
 Cell-Cell Communication Pathway antibodies  Cell-Cell Communication Pathway Diagram
 Collagen Biosynthesis And Modifying Enzymes Pathway antibodies  Collagen Biosynthesis And Modifying Enzymes Pathway Diagram
 Collagen Degradation Pathway antibodies  Collagen Degradation Pathway Diagram
 Collagen Formation Pathway antibodies  Collagen Formation Pathway Diagram
 Degradation Of The Extracellular Matrix Pathway antibodies  Degradation Of The Extracellular Matrix Pathway Diagram
 Extracellular Matrix Organization Pathway antibodies  Extracellular Matrix Organization Pathway Diagram
 Protein Digestion And Absorption Pathway antibodies  Protein Digestion And Absorption Pathway Diagram
 Protein Digestion And Absorption Pathway antibodies  Protein Digestion And Absorption Pathway Diagram
Diseases associated with COL17A1 elisa kitOrgans/Tissues associated with COL17A1 elisa kit
 Disease Name  Pubmed Publications
 Carcinoma Antibodies  >8 publications with COL17A1 and Carcinoma
 Carcinoma, Squamous Cell Antibodies  >8 publications with COL17A1 and Carcinoma, Squamous Cell
 Skin Neoplasms Antibodies  >4 publications with COL17A1 and Skin Neoplasms
 Hyperplasia Antibodies  >2 publications with COL17A1 and Hyperplasia
 Fetal Death Antibodies  >1 publications with COL17A1 and Fetal Death
 Nervous System Malformations Antibodies  >1 publications with COL17A1 and Nervous System Malformations
 Fibrosis Antibodies  >1 publications with COL17A1 and Fibrosis
 Melanoma Antibodies  >1 publications with COL17A1 and Melanoma
 Neoplasm Invasiveness Antibodies  >1 publications with COL17A1 and Neoplasm Invasiveness
 Cell Transformation, Neoplastic Antibodies  >1 publications with COL17A1 and Cell Transformation, Neoplastic
 Organ/Tissue Name  Pubmed Publications
 Skin Antibodies  >57 publications with COL17A1 and Skin
 Blood Antibodies  >5 publications with COL17A1 and Blood
 Mouth Antibodies  >4 publications with COL17A1 and Mouth
 Eye Antibodies  >4 publications with COL17A1 and Eye
 Lung Antibodies  >2 publications with COL17A1 and Lung
 Embryonic Tissue Antibodies  >1 publications with COL17A1 and Embryonic Tissue
 Kidney Antibodies  >1 publications with COL17A1 and Kidney
 Brain Antibodies  >1 publications with COL17A1 and Brain
 Intestine Antibodies  >1 publications with COL17A1 and Intestine
 Bladder Antibodies  >1 publications with COL17A1 and Bladder
Table BarTOPTable Bar
horiz bar
 SSL   Follow us on Facebook Follow us onTwitter Follow us on Google Plus Connect us on LinkedIn Subscribe to our RSS Feed for latest products and special promotions