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CFD elisa kit :: Human Complement Factor D (CFD) ELISA Kit

Scan QR to view Datasheet Catalog #    MBS455969 (SPECIAL PROMOTIONAL PRICING for a limited time)
Typical Testing Data/Standard Curve (for reference only)
Unit / Price
48-Strip-Wells  /  $290 +1 FREE 8GB USB
96-Strip-Wells  /  $365 +1 FREE 8GB USB
5x96-Strip-Wells  /  $1,590 +1 FREE 8GB USB
10x96-Strip-Wells  /  $3,065 +3 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Complement Factor D (CFD), ELISA Kit

★Popular Item★
 Also Known As   

Human Complement Factor D (CFD) ELISA Kit

 Product Synonym Names    CF-D; DF; PFD; ADN; Adipsin; Properdin Factor D; C3 convertase activator
 Product Gene Name   

CFD elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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  Sample Manual Insert    Download PDF Manual View PDF Manual
 Request for Current Manual Insert    Request Current Manual
 OMIM    AJ313463 mRNA
 3D Structure    ModBase 3D Structure for P00746
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 Species Reactivity    Human
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 Samples    Serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids.
 Assay Type    Sandwich
 Detection Range    0.312-20ng/mL
 Sensitivity    0.137ng/mL
 Intra Assay    CV<10%
 Inter Assay    CV<12%
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 Preparation and Storage    For unopened kit, all reagents should be kept according to the labels on vials. The TMB Substrate, Wash Buffer, Stop Solution should be stored at 4 degree C. All others should be stored at -20 degree C.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of CFD elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for CFD purchase    MBS455969 is a ready-to-use microwell, strip plate Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Complement Factor D (CFD) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range of 0.312-20ng/mL in biological research samples containing CFD, with an estimated sensitivity of 0.137ng/mL. The ELISA analytical biochemical technique of the MBS455969 kit is based on CFD antibody-CFD antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect CFD antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, CFD. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions such as Serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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 Typical Testing Data/Standard Curve (for reference only) of CFD elisa kit    CFD elisa kit Typical Testing Data/Standard Curve (for reference only) image
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Sample Manual Insert of MBS455969. Click to request current manual
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NCBI/Uniprot data below describe general gene information for CFD. It may not necessarily be applicable to this product.
 NCBI GI #    955654851
 NCBI GeneID    1675
 NCBI Accession #    NP_001304264.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001317335.1 [Other Products]
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 UniProt Primary Accession #    P00746 [Other Products]
 UniProt Secondary Accession #    Q5U5S1; Q86VJ5; Q8N4E0; Q8WZB4; B4DV76 [Other Products]
 UniProt Related Accession #    P00746 [Other Products]
 Molecular Weight    27,033 Da
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 NCBI Official Full Name    complement factor D isoform 2
 NCBI Official Synonym Full Names    complement factor D
 NCBI Official Symbol    CFD [Similar Products]
 NCBI Official Synonym Symbols   
DF; ADN; PFD; ADIPSIN
[Similar Products]
 NCBI Protein Information    complement factor D
 UniProt Protein Name    Complement factor D
 UniProt Synonym Protein Names   
Adipsin; C3 convertase activator; Properdin factor D
 Protein Family    Complement factor
 UniProt Gene Name    CFD [Similar Products]
 UniProt Synonym Gene Names    DF; PFD [Similar Products]
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 NCBI Summary for CFD    This gene encodes a member of the S1, or chymotrypsin, family of serine peptidases. This protease catalyzes the cleavage of factor B, the rate-limiting step of the alternative pathway of complement activation. This protein also functions as an adipokine, a cell signaling protein secreted by adipocytes, which regulates insulin secretion in mice. Mutations in this gene underlie complement factor D deficiency, which is associated with recurrent bacterial meningitis infections in human patients. Alternative splicing of this gene results in multiple transcript variants. At least one of these variants encodes a preproprotein that is proteolytically processed to generate the mature protease. [provided by RefSeq, Nov 2015]
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 UniProt Comments for CFD    Factor D cleaves factor B when the latter is complexed with factor C3b, activating the C3bbb complex, which then becomes the C3 convertase of the alternate pathway. Its function is homologous to that of C1s in the classical pathway.
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 Research Articles on CFD    1. our findings set up a novel mechanism for FABP4, adipsin and adiponectin through gut microbiota mediating expression in gut Paneth cells.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with CFD elisa kitPathways associated with CFD elisa kit
 Reference Product  PubMed Publications
 SPARC elisa kit  >1 publications with CFD and SPARC
 INS elisa kit  >1 publications with CFD and INS
 SERPING1 elisa kit  >1 publications with CFD and SERPING1
 SERPINE1 elisa kit  >1 publications with CFD and SERPINE1
 Products by Pathway  Pathway Diagram
 Adipogenesis Pathway antibodies  Adipogenesis Pathway Diagram
 Alternative Complement Activation Pathway antibodies  Alternative Complement Activation Pathway Diagram
 Complement Activation Pathway antibodies  Complement Activation Pathway Diagram
 Complement And Coagulation Cascades Pathway antibodies  Complement And Coagulation Cascades Pathway Diagram
 Complement And Coagulation Cascades Pathway antibodies  Complement And Coagulation Cascades Pathway Diagram
 Complement And Coagulation Cascades Pathway antibodies  Complement And Coagulation Cascades Pathway Diagram
 Complement Cascade Pathway antibodies  Complement Cascade Pathway Diagram
 Hemostasis Pathway antibodies  Hemostasis Pathway Diagram
 Immune System Pathway antibodies  Immune System Pathway Diagram
 Initial Triggering Of Complement Pathway antibodies  Initial Triggering Of Complement Pathway Diagram
Diseases associated with CFD elisa kitOrgans/Tissues associated with CFD elisa kit
 Disease Name  Pubmed Publications
 Cardiovascular Diseases Antibodies  >514 publications with CFD and Cardiovascular Diseases
 Heart Diseases Antibodies  >149 publications with CFD and Heart Diseases
 Heart Failure Antibodies  >56 publications with CFD and Heart Failure
 Hyperplasia Antibodies  >35 publications with CFD and Hyperplasia
 Disease Models, Animal Antibodies  >27 publications with CFD and Disease Models, Animal
 Inflammation Antibodies  >25 publications with CFD and Inflammation
 Carcinoma Antibodies  >22 publications with CFD and Carcinoma
 Hypertension Antibodies  >19 publications with CFD and Hypertension
 Liver Diseases Antibodies  >17 publications with CFD and Liver Diseases
 Kidney Diseases Antibodies  >11 publications with CFD and Kidney Diseases
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >894 publications with CFD and Blood
 Vascular Antibodies  >595 publications with CFD and Vascular
 Heart Antibodies  >355 publications with CFD and Heart
 Lung Antibodies  >139 publications with CFD and Lung
 Brain Antibodies  >101 publications with CFD and Brain
 Bone Antibodies  >84 publications with CFD and Bone
 Mouth Antibodies  >65 publications with CFD and Mouth
 Liver Antibodies  >40 publications with CFD and Liver
 Muscle Antibodies  >37 publications with CFD and Muscle
 Pharynx Antibodies  >33 publications with CFD and Pharynx
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