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COTININE elisa kit :: Human Cotinine ELISA Kit

Scan QR to view Datasheet Catalog #    MBS019457
Typical Testing Data/Standard Curve (for reference only)
Unit / Price
48-Strip-Wells  /  $500 +1 FREE 8GB USB
96-Strip-Wells  /  $710 +1 FREE 8GB USB
5x96-Strip-Wells  /  $3,250 +4 FREE 8GB USB
10x96-Strip-Wells  /  $6,395 +7 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Cotinine, ELISA Kit

★Popular Item★
 Also Known As   

Human Cotinine ELISA Kit

 Product Gene Name   

COTININE elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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  Sample Manual Insert    Download PDF Manual View PDF Manual
 Request for Current Manual Insert    Request Current Manual
 OMIM    605608
 3D Structure    ModBase 3D Structure for O95500
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 Species Reactivity    Human
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 Specificity    No significant cross-reactivity or interference between this analyte and analogues is observed.
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 Samples    undiluted original Human body fluids, tissue homogenates, secretions or feces samples
 Assay Type    Quantitative Sandwich
 Detection Range    0.5 ng/ml - 16 ng/mL
 Sensitivity    0.1 ng/mL
 Intra-assay Precision    Intra-assay CV (%) is less than 15%.
 Inter-assay Precision    Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean 100].
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 Preparation and Storage    Store all reagents at 2-8 degree C
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of COTININE elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for COTININE purchase    MBS019457 is a ready-to-use microwell, strip plate Quantitative Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Cotinine, ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range of 0.5 ng/ml - 16 ng/mL in biological research samples containing COTININE, with an estimated sensitivity of 0.1 ng/mL. The ELISA analytical biochemical technique of the MBS019457 kit is based on COTININE antibody-COTININE antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect COTININE antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, COTININE. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions such as undiluted original Human body fluids, tissue homogenates, secretions or feces samples. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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Related Product Information for COTININE elisa kit

   Background: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of CTN (hereafter termed "analyte") in undiluted original Human body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.
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 Typical Testing Data/Standard Curve (for reference only) of COTININE elisa kit    COTININE elisa kit Typical Testing Data/Standard Curve (for reference only) image
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Sample Manual Insert of MBS019457. Click to request current manual
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NCBI/Uniprot data below describe general gene information for COTININE. It may not necessarily be applicable to this product.
 NCBI GI #    225703140
 NCBI GeneID    23562
 NCBI Accession #    NP_001139550.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001146078.2 [Other Products]
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 UniProt Primary Accession #    O95500 [Other Products]
 UniProt Related Accession #    O95500 [Other Products]
 Molecular Weight    25,699 Da
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 NCBI Official Full Name    claudin-14
 NCBI Official Synonym Full Names    claudin 14
 NCBI Official Symbol    CLDN14 [Similar Products]
 NCBI Official Synonym Symbols   
DFNB29
[Similar Products]
 NCBI Protein Information    claudin-14
 UniProt Protein Name    Claudin-14
 UniProt Gene Name    CLDN14 [Similar Products]
 UniProt Entry Name    CLD14_HUMAN
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 NCBI Summary for COTININE    Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. The protein encoded by this gene, a member of the claudin family, is an integral membrane protein and a component of tight junction strands. The encoded protein also binds specifically to the WW domain of Yes-associated protein. Defects in this gene are the cause of an autosomal recessive form of nonsyndromic sensorineural deafness. It is also reported that four synonymous variants in this gene are associated with kidney stones and reduced bone mineral density. Several transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jun 2010]
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 UniProt Comments for COTININE    Claudin-14: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium- independent cell-adhesion activity. Defects in CLDN14 are the cause of deafness autosomal recessive type 29 (DFNB29). DFNB29 is a form of sensorineural hearing loss. Sensorineural deafness results from damage to the neural receptors of the inner ear, the nerve pathways to the brain, or the area of the brain that receives sound information. Belongs to the claudin family.

Protein type: Membrane protein, integral; Membrane protein, multi-pass; Cell adhesion

Chromosomal Location of Human Ortholog: 21q22.3

Cellular Component: tight junction; endoplasmic reticulum; integral to membrane; plasma membrane

Molecular Function: identical protein binding; structural molecule activity

Biological Process: intercellular junction assembly and maintenance; protein complex assembly; calcium-independent cell-cell adhesion

Disease: Deafness, Autosomal Recessive 29
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 Research Articles on COTININE    1. Claudin 14 expression was up-regulated in gastric cancer.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with COTININE elisa kitPathways associated with COTININE elisa kit
 Reference Product  PubMed Publications
 TJP2 elisa kit  >1 publications with COTININE and TJP2
 CLDN9 elisa kit  >1 publications with COTININE and CLDN9
 CLDN12 elisa kit  >1 publications with COTININE and CLDN12
 Products by Pathway  Pathway Diagram
 Cell Adhesion Molecules (CAMs) Pathway antibodies  Cell Adhesion Molecules (CAMs) Pathway Diagram
 Cell Adhesion Molecules (CAMs) Pathway antibodies  Cell Adhesion Molecules (CAMs) Pathway Diagram
 Cell Junction Organization Pathway antibodies  Cell Junction Organization Pathway Diagram
 Cell-Cell Communication Pathway antibodies  Cell-Cell Communication Pathway Diagram
 Cell-cell Junction Organization Pathway antibodies  Cell-cell Junction Organization Pathway Diagram
 Hepatitis C Pathway antibodies  Hepatitis C Pathway Diagram
 Hepatitis C Pathway antibodies  Hepatitis C Pathway Diagram
 Leukocyte Transendothelial Migration Pathway antibodies  Leukocyte Transendothelial Migration Pathway Diagram
 Leukocyte Transendothelial Migration Pathway antibodies  Leukocyte Transendothelial Migration Pathway Diagram
 Tight Junction Pathway antibodies  Tight Junction Pathway Diagram
Diseases associated with COTININE elisa kit
 Disease Name  Pubmed Publications
 Deafness Antibodies  >10 publications with COTININE and Deafness
 Kidney Diseases Antibodies  >4 publications with COTININE and Kidney Diseases
 Kidney Calculi Antibodies  >2 publications with COTININE and Kidney Calculi
 Inflammation Antibodies  >1 publications with COTININE and Inflammation
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