AAA60299.1
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
16,388 Da
NCBI Official Full Name
cystatin
NCBI Official Synonym Full Names
cystatin SN
NCBI Protein Information
cystatin-SN; cystatin 1; cystatin-1; cystain-SA-I; cystatin SA-I; salivary cystatin-SA-1; cysteine proteinase inhibitor, type 2 family
UniProt Protein Name
Cystatin-SN
UniProt Synonym Protein Names
Cystain-SA-I; Cystatin-1; Salivary cystatin-SA-1
UniProt Entry Name
CYTN_HUMAN
NCBI Summary for CST3
The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins and the kininogens. The type 2 cystatin proteins are a class of cysteine proteinase inhibitors found in a variety of human fluids and secretions, where they appear to provide protective functions. The cystatin locus on chromosome 20 contains the majority of the type 2 cystatin genes and pseudogenes. This gene is located in the cystatin locus and encodes a cysteine proteinase inhibitor found in saliva, tears, urine, and seminal fluid. [provided by RefSeq, Jul 2008]
UniProt Comments for CST3
CST1: Human saliva appears to contain several cysteine proteinase inhibitors that are immunologically related to cystatin S but that differ in their specificity due to amino acid sequence differences. Cystatin SN, with a pI of 7.5, is a much better inhibitor of papain and dipeptidyl peptidase I than is cystatin S, although both inhibit ficin equally well. Belongs to the cystatin family.
Protein type: Secreted, signal peptide; Secreted
Chromosomal Location of Human Ortholog: 20p11.21
Cellular Component: extracellular space
Molecular Function: cysteine protease inhibitor activity
Biological Process: detection of chemical stimulus involved in sensory perception of bitter taste
Research Articles on CST3
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Pathways associated with CST3 elisa kit
Diseases associated with CST3 elisa kit
Organs/Tissues associated with CST3 elisa kit
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