NP_001192195.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
Molecular Weight
7,038 Da
NCBI Official Full Name
beta-defensin 4B
NCBI Official Synonym Full Names
defensin beta 4B
NCBI Official Synonym Symbols
NCBI Protein Information
beta-defensin 4B
UniProt Protein Name
Beta-defensin 4A
UniProt Synonym Protein Names
Beta-defensin 2; BD-2; hBD-2; Defensin, beta 2; Skin-antimicrobial peptide 1; SAP1
UniProt Synonym Gene Names
NCBI Summary for DEFb2
Defensins form a family of microbicidal and cytotoxic peptides made by neutrophils. Members of the defensin family are highly similar in protein sequence. This gene encodes defensin, beta 4, an antibiotic peptide which is locally regulated by inflammation. [provided by RefSeq, Oct 2014]
UniProt Comments for DEFb2
defensin, beta 2: Has antibacterial activity (Potential). Belongs to the beta-defensin family. LAP/TAP subfamily.
Protein type: Motility/polarity/chemotaxis; Secreted; Secreted, signal peptide
Chromosomal Location of Human Ortholog: 8p23.1
Cellular Component: extracellular region; extracellular space; Golgi lumen
Molecular Function: CCR6 chemokine receptor binding; protein binding
Biological Process: chemotaxis; defense response to bacterium; defense response to Gram-negative bacterium; defense response to Gram-positive bacterium; G-protein coupled receptor protein signaling pathway; immune response; innate immune response
Research Articles on DEFb2
Precautions
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Disclaimer
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Pathways associated with DEFb2 elisa kit
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