NP_061947.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
74,605 Da
NCBI Official Full Name
delta-like protein 4
NCBI Official Synonym Full Names
delta-like 4 (Drosophila)
NCBI Official Synonym Symbols
NCBI Protein Information
delta-like protein 4; delta4; delta 4; delta ligand 4; notch ligand DLL4; delta-like 4 homolog; delta-like 4 protein; notch ligand delta-2; drosophila Delta homolog 4
UniProt Protein Name
Delta-like protein 4
UniProt Synonym Protein Names
Drosophila Delta homolog 4
UniProt Synonym Gene Names
UniProt Entry Name
DLL4_HUMAN
NCBI Summary for dLL4
This gene is a homolog of the Drosophila delta gene. The delta gene family encodes Notch ligands that are characterized by a DSL domain, EGF repeats, and a transmembrane domain. [provided by RefSeq, Jul 2008]
UniProt Comments for dLL4
DLL4: Plays a role in the Notch signaling pathway. Activates Notch-1 and Notch-4. Binds to Notch-1 and Notch-4. Expressed in vascular endothelium.
Protein type: Membrane protein, integral; Cell development/differentiation
Chromosomal Location of Human Ortholog: 15q14
Cellular Component: plasma membrane; integral to membrane
Molecular Function: calcium ion binding; Notch binding
Biological Process: patterning of blood vessels; negative regulation of cell proliferation; Notch signaling pathway; regulation of neurogenesis; visual perception; blood circulation; Notch receptor processing; blood vessel remodeling; angiogenesis; negative regulation of transcription from RNA polymerase II promoter; signal transduction
Research Articles on dLL4
Precautions
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Products associated with dLL4 elisa kit
Pathways associated with dLL4 elisa kit
Diseases associated with dLL4 elisa kit
Organs/Tissues associated with dLL4 elisa kit
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