NP_932065.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
83,398 Da
NCBI Official Full Name
dipeptidyl peptidase 8 isoform 4
NCBI Official Synonym Full Names
dipeptidyl-peptidase 8
NCBI Official Synonym Symbols
DP8; DPRP1; MST097; MSTP097; MSTP135; MSTP141 [Similar Products]
NCBI Protein Information
dipeptidyl peptidase 8
UniProt Protein Name
Dipeptidyl peptidase 8
UniProt Synonym Protein Names
Dipeptidyl peptidase IV-related protein 1; DPRP-1; Dipeptidyl peptidase VIII; DPP VIII; Prolyl dipeptidase DPP8
UniProt Synonym Gene Names
UniProt Entry Name
DPP8_HUMAN
NCBI Summary for DPP8
This gene encodes a member of the peptidase S9B family, a small family of dipeptidyl peptidases that are able to cleave peptide substrates at a prolyl bond. The encoded protein shares similarity with dipeptidyl peptidase IV in that it is ubiquitously expressed, and hydrolyzes the same substrates. These similarities suggest that, like dipeptidyl peptidase IV, this protein may play a role in T-cell activation and immune function. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008]
UniProt Comments for DPP8
DPP8: Dipeptidyl peptidase that cleaves off N-terminal dipeptides from proteins having a Pro or Ala residue at position 2. May play a role in T-cell activation and immune function. Belongs to the peptidase S9B family. DPPIV subfamily. 6 isoforms of the human protein are produced by alternative splicing.
Protein type: EC 3.4.14.5; Protease
Chromosomal Location of Human Ortholog: 15q22
Cellular Component: nucleoplasm; membrane; cytoplasm
Molecular Function: dipeptidyl-peptidase activity; serine-type peptidase activity
Biological Process: immune response; proteolysis
Research Articles on DPP8
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Diseases associated with DPP8 elisa kit
Organs/Tissues associated with DPP8 elisa kit
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