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ELAVL1 elisa kit :: Human ELAV (embryonic lethal, abnormal vision, Drosophila) -like 1 (Hu antigen R) ELISA Kit

Scan QR to view Datasheet Catalog #    MBS919324
Typical Testing Data/Standard Curve (for reference only)
Unit / Price
24-Strip-Wells (LIMIT 1)  /  $250 +1 FREE 8GB USB
48-Strip-Wells  /  $495 +1 FREE 8GB USB
96-Strip-Wells  /  $710 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,705 +3 FREE 8GB USB
10x96-Strip-Wells  /  $5,145 +6 FREE 8GB USB
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

ELAV (embryonic lethal, abnormal vision, Drosophila) -like 1 (Hu antigen R) (ELAVL1), ELISA Kit

★Popular Item★
 Also Known As   

Human ELAV-like protein 1, ELAVL1 ELISA Kit

 Product Synonym Names    Human ELAV-like protein 1 (ELAVL1) ELISA kit; ELAV1; HUR; Hua; MelG; ELAV-like 1; Hu antigen R; embryonic lethal; abnormal vision; drosophila; homolog-like 1; ELAV (embryonic lethal; abnormal vision; Drosophila) -like 1 (Hu antigen R)
 Product Gene Name   

ELAVL1 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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  Sample Manual Insert    Download PDF Manual View PDF Manual
 Request for Current Manual Insert    Request Current Manual
 MBS919324 Testing Data    Testing Data PDF
 OMIM    603466
 3D Structure    ModBase 3D Structure for Q15717
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 Species Reactivity    Human
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 Specificity    This assay has high sensitivity and excellent specificity for detection of human ELAVL1. No significant cross-reactivity or interference between human ELAVL1 and analogues was observed.
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 Samples    Serum, plasma, tissue homogenates, cell lysates.
 Assay Type    Sandwich
 Detection Range    25 pg/ml-1600 pg/ml.
 Sensitivity    Typically less than 6.25 pg/ml
 Intra-assay Precision    Intra-assay Precision (Precision within an assay): CV%<8%. Three samples of known concentration were tested twenty times on one plate to assess.
 Inter-assay Precision    Inter-assay Precision (Precision between assays): CV%<10%. Three samples of known concentration were tested in twenty assays to assess.
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 Preparation and Storage    Unopened test kits should be stored at 2 to 8 degree C upon receipt. Please refer to pdf manual for further storage instructions.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of ELAVL1 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for ELAVL1 purchase    MBS919324 is a ready-to-use microwell, strip plate Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the ELAV (embryonic lethal, abnormal vision, Drosophila) -like 1 (Hu antigen R) (ELAVL1) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range of 25 pg/ml-1600 pg/ml in biological research samples containing ELAVL1, with an estimated sensitivity of Typically less than 6.25 pg/ml. The ELISA analytical biochemical technique of the MBS919324 kit is based on ELAVL1 antibody-ELAVL1 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect ELAVL1 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, ELAVL1. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions such as Serum, plasma, tissue homogenates, cell lysates. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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Related Product Information for ELAVL1 elisa kit

   Principle of the Assay: This assay employs the quantitative sandwich enzyme immunoassay technique. Antibody specific for ELAVL1 has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and any ELAVL1 present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for ELAVL1 is added to the wells. After washing, avidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of ELAVL1 bound in the initial step. The color development is stopped and the intensity of the color is measured.
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 Typical Testing Data/Standard Curve (for reference only) of ELAVL1 elisa kit    ELAVL1 elisa kit Typical Testing Data/Standard Curve (for reference only) image
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Sample Manual Insert of MBS919324. Click to request current manual
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NCBI/Uniprot data below describe general gene information for ELAVL1. It may not necessarily be applicable to this product.
 NCBI GI #    38201714
 NCBI GeneID    1994
 NCBI Accession #    NP_001410.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_001419.2 [Other Products]
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 UniProt Primary Accession #    Q15717 [Other Products]
 UniProt Secondary Accession #    Q53XN6; Q9BTT1 [Other Products]
 UniProt Related Accession #    Q15717 [Other Products]
 Molecular Weight    36,092 Da
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 NCBI Official Full Name    ELAV-like protein 1
 NCBI Official Synonym Full Names    ELAV like RNA binding protein 1
 NCBI Official Symbol    ELAVL1 [Similar Products]
 NCBI Official Synonym Symbols   
HUR; Hua; MelG; ELAV1
[Similar Products]
 NCBI Protein Information    ELAV-like protein 1; Hu antigen R; hu-antigen R; embryonic lethal, abnormal vision, drosophila, homolog-like 1; ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R)
 UniProt Protein Name    ELAV-like protein 1
 UniProt Synonym Protein Names   
Hu-antigen R; HuR
 Protein Family    ELAV-like protein
 UniProt Gene Name    ELAVL1 [Similar Products]
 UniProt Synonym Gene Names    HUR; HuR [Similar Products]
 UniProt Entry Name    ELAV1_HUMAN
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 NCBI Summary for ELAVL1    The protein encoded by this gene is a member of the ELAVL family of RNA-binding proteins that contain several RNA recognition motifs, and selectively bind AU-rich elements (AREs) found in the 3' untranslated regions of mRNAs. AREs signal degradation of mRNAs as a means to regulate gene expression, thus by binding AREs, the ELAVL family of proteins play a role in stabilizing ARE-containing mRNAs. This gene has been implicated in a variety of biological processes and has been linked to a number of diseases, including cancer. It is highly expressed in many cancers, and could be potentially useful in cancer diagnosis, prognosis, and therapy. [provided by RefSeq, Sep 2012]
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 UniProt Comments for ELAVL1    HuR: Involved in 3'-UTR ARE-mediated MYC stabilization. Binds avidly to the AU-rich element in FOS and IL3/interleukin-3 mRNAs. In the case of the FOS AU-rich element, HUR binds to a core element of 27 nucleotides that contain AUUUA, AUUUUA and AUUUUUA motifs. Binds preferentially to the 5'-UUUU[AG]UUU-3' motif in vitro. Identified in a mRNP complex, at least composed of DHX9, DDX3X, ELAVL1, HNRNPU, IGF2BP1, ILF3, PABPC1, PCBP2, PTBP2, STAU1, STAU2, SYNCRIP and YBX1. Interacts with ANP32A, EIF2C1 and EIF2C2. Ubiquitous. Belongs to the RRM elav family.

Protein type: RNA-binding

Chromosomal Location of Human Ortholog: 19p13.2

Cellular Component: nucleoplasm; membrane; cytoplasm; cytosol; nucleus

Molecular Function: mRNA binding; protein binding; mRNA 3'-UTR binding; RNA binding; double-stranded RNA binding; nucleotide binding; AU-rich element binding; protein kinase binding

Biological Process: positive regulation of translation; mRNA stabilization; multicellular organismal development; gene expression
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 Research Articles on ELAVL1    1. The overexpression of a HuR mutant that could not be phosphorylated blocked the associated TRA2beta4 interaction.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with ELAVL1 elisa kitPathways associated with ELAVL1 elisa kit
 Reference Product  PubMed Publications
 SET elisa kit  >7 publications with ELAVL1 and SET
 ANP32B elisa kit  >7 publications with ELAVL1 and ANP32B
 ANP32A elisa kit  >5 publications with ELAVL1 and ANP32A
 TNPO2 elisa kit  >4 publications with ELAVL1 and TNPO2
 TNPO1 elisa kit  >1 publications with ELAVL1 and TNPO1
 CARM1 elisa kit  >1 publications with ELAVL1 and CARM1
 Products by Pathway  Pathway Diagram
 Gene Expression Pathway antibodies  Gene Expression Pathway Diagram
 Regulation Of MRNA Stability By Proteins That Bind AU-rich Elements Pathway antibodies  Regulation Of MRNA Stability By Proteins That Bind AU-rich Elements Pathway Diagram
 Stabilization Of MRNA By HuR Pathway antibodies  Stabilization Of MRNA By HuR Pathway Diagram
Diseases associated with ELAVL1 elisa kitOrgans/Tissues associated with ELAVL1 elisa kit
 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >105 publications with ELAVL1 and Neoplasms
 Carcinoma Antibodies  >59 publications with ELAVL1 and Carcinoma
 Necrosis Antibodies  >30 publications with ELAVL1 and Necrosis
 Adenocarcinoma Antibodies  >24 publications with ELAVL1 and Adenocarcinoma
 Inflammation Antibodies  >23 publications with ELAVL1 and Inflammation
 Death Antibodies  >12 publications with ELAVL1 and Death
 Endocrine Gland Neoplasms Antibodies  >9 publications with ELAVL1 and Endocrine Gland Neoplasms
 Kidney Neoplasms Antibodies  >9 publications with ELAVL1 and Kidney Neoplasms
 Disease Models, Animal Antibodies  >9 publications with ELAVL1 and Disease Models, Animal
 Carcinoma, Hepatocellular Antibodies  >7 publications with ELAVL1 and Carcinoma, Hepatocellular
 Organ/Tissue Name  Pubmed Publications
 Eye Antibodies  >3 publications with ELAVL1 and Eye
 Parathyroid Antibodies  >1 publications with ELAVL1 and Parathyroid
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