NP_001158110.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
30,792 Da
NCBI Official Full Name
endonuclease V isoform 3
NCBI Official Synonym Full Names
endonuclease V
NCBI Protein Information
endonuclease V
UniProt Protein Name
Endonuclease V
UniProt Entry Name
ENDOV_HUMAN
UniProt Comments for ENDOV
ENDOV: Selectively cleaves DNA at the second phosphodiester bond 3' to hypoxanthine- and uracil-containing nucleotides. Shows higher activity towards single-stranded than double-stranded DNA and towards hypoxanthine than uracil. Belongs to the endonuclease V family. 4 isoforms of the human protein are produced by alternative splicing.
Protein type: EC 3.1.21.-; EC 3.1.-.-; Nucleolus; Hydrolase
Chromosomal Location of Human Ortholog: 17q25.3
Cellular Component: cytoplasm; nucleolus
Molecular Function: endodeoxyribonuclease activity, producing 5'-phosphomonoesters; single-stranded RNA binding; structure-specific DNA binding; magnesium ion binding; endoribonuclease activity, producing 5'-phosphomonoesters
Biological Process: DNA repair; DNA catabolic process, endonucleolytic
Research Articles on ENDOV
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Organs/Tissues associated with ENDOV elisa kit
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