Q9H469.2
[Other Products]
UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
F-box/LRR-repeat protein 15
NCBI Official Synonym Full Names
F-box and leucine-rich repeat protein 15
NCBI Protein Information
F-box/LRR-repeat protein 15; F-box only protein 37; pleckstrin and Sec7 domain protein
UniProt Protein Name
F-box/LRR-repeat protein 15
UniProt Synonym Protein Names
F-box only protein 37
UniProt Synonym Gene Names
UniProt Entry Name
FXL15_HUMAN
UniProt Comments for FBXL15
FBXL15: Substrate recognition component of a (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of SMURF1, thereby acting as a positive regulator of the BMP signaling pathway. Required for dorsal/ventral pattern formation and bone mass maintenance. Also mediates ubiquitination of SMURF2 and WWP2. Belongs to the FBXL15 family.
Chromosomal Location of Human Ortholog: 10q24.32
Cellular Component: cytoplasm; SCF ubiquitin ligase complex
Molecular Function: protein binding; ubiquitin-protein ligase activity
Biological Process: SCF-dependent proteasomal ubiquitin-dependent protein catabolic process; dorsal/ventral pattern formation; protein ubiquitination; G2/M transition of mitotic cell cycle; positive regulation of BMP signaling pathway; bone mineralization
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice. It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Products associated with FBXL15 elisa kit
Organs/Tissues associated with FBXL15 elisa kit
|