NP_001014765.1
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NCBI GenBank Nucleotide #
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UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
F-box only protein 44 isoform 1
NCBI Official Synonym Full Names
F-box protein 44
NCBI Official Synonym Symbols
FBG3; FBX30; FBX6A; Fbx44; Fbxo6a [Similar Products]
NCBI Protein Information
F-box only protein 44; F-box gene 3; F-box protein FBX30; F-box/G-domain protein 3
UniProt Protein Name
F-box only protein 44
UniProt Synonym Protein Names
F-box protein FBX30; F-box/G-domain protein 3
UniProt Synonym Gene Names
UniProt Entry Name
FBX44_HUMAN
NCBI Summary for FBXO44
This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class. It is also a member of the NFB42 (neural F Box 42 kDa) family, similar to F-box only protein 2 and F-box only protein 6. Four alternatively spliced transcript variants encoding two distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
UniProt Comments for FBXO44
FBXO44: Substrate-recognition component of the SCF (SKP1-CUL1-F- box protein)-type E3 ubiquitin ligase complex. 2 isoforms of the human protein are produced by alternative splicing.
Chromosomal Location of Human Ortholog: 1p36.22
Cellular Component: SCF ubiquitin ligase complex
Molecular Function: protein binding
Research Articles on FBXO44
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Pathways associated with FBXO44 elisa kit
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