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FASN elisa kit :: Human FASN ELISA Kit

Scan QR to view Datasheet Catalog #    MBS2507799
Typical Testing Data/Standard Curve (for reference only)
Unit / Price
48-Strip-Wells  /  $410 +1 FREE 8GB USB
96-Strip-Wells  /  $490 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,040 +2 FREE 8GB USB
10x96-Strip-Wells  /  $3,590 +4 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

FASN, ELISA Kit

★Popular Item★
 Also Known As   

Human FASN(Fatty Acid Synthase)ELISA Kit

 Product Gene Name   

FASN elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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  Sample Manual Insert    Download PDF Manual View PDF Manual
 Request for Current Manual Insert    Request Current Manual
 MBS2507799 COA    COA PDF
 MBS2507799 Testing Data    Testing Data PDF
 OMIM    600212
 3D Structure    ModBase 3D Structure for P49327
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 Species Reactivity    Human
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 Specificity    This kit recognizes Human FASN in samples. No Significant cross-reactivity or interference between Human FASN and analogues was observed.
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 Samples    Serum, Plasma, Biological Fluids
 Assay Type    Sandwich
 Detection Range    0.313-20ng/mL
 Sensitivity    Min: 0.188ng/mL; Max: 20ng/mL
 Intra-assay Precision    Intra-assay Precision (Precision within an assay): 3 samples with low, mid range and high level Human FASN were tested 20 times on one plate, respectively.
 Inter-assay Precision    Inter-assay Precision (Precision between assays): 3 samples with low, mid range and high level Human FASN were tested on 3 different plates, 20 replicates in each plate.
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 Preparation and Storage    Store at 4 degree C.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of FASN elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for FASN purchase    MBS2507799 is a ready-to-use microwell, strip plate Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the FASN, ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range of 0.313-20ng/mL in biological research samples containing FASN, with an estimated sensitivity of Min: 0.188ng/mL; Max: 20ng/mL. The ELISA analytical biochemical technique of the MBS2507799 kit is based on FASN antibody-FASN antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect FASN antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, FASN. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions such as Serum, Plasma, Biological Fluids. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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Related Product Information for FASN elisa kit

   Intended Uses: This ELISA kit applies to the in vitro quantitative determination of Human FASN concentrations in serum, plasma and other biological fluids.
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 Typical Testing Data/Standard Curve (for reference only) of FASN elisa kit    FASN elisa kit Typical Testing Data/Standard Curve (for reference only) image
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Sample Manual Insert of MBS2507799. Click to request current manual
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NCBI/Uniprot data below describe general gene information for FASN. It may not necessarily be applicable to this product.
 NCBI GI #    41872631
 NCBI GeneID    2194
 NCBI Accession #    NP_004095.4 [Other Products]
 NCBI GenBank Nucleotide #    NM_004104.4 [Other Products]
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 UniProt Primary Accession #    P49327 [Other Products]
 UniProt Secondary Accession #    Q13479; Q16702; Q4LE83; Q6P4U5; Q6SS02; Q969R1; Q96C68; Q96IT0 [Other Products]
 UniProt Related Accession #    P49327 [Other Products]
 Molecular Weight    273,427 Da
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 NCBI Official Full Name    fatty acid synthase
 NCBI Official Synonym Full Names    fatty acid synthase
 NCBI Official Symbol    FASN [Similar Products]
 NCBI Official Synonym Symbols   
FAS; OA-519; SDR27X1
[Similar Products]
 NCBI Protein Information    fatty acid synthase; short chain dehydrogenase/reductase family 27X, member 1
 UniProt Protein Name    Fatty acid synthase
 Protein Family    Fatty acid synthase
 UniProt Gene Name    FASN [Similar Products]
 UniProt Synonym Gene Names    FAS [Similar Products]
 UniProt Entry Name    FAS_HUMAN
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 NCBI Summary for FASN    The enzyme encoded by this gene is a multifunctional protein. Its main function is to catalyze the synthesis of palmitate from acetyl-CoA and malonyl-CoA, in the presence of NADPH, into long-chain saturated fatty acids. In some cancer cell lines, this protein has been found to be fused with estrogen receptor-alpha (ER-alpha), in which the N-terminus of FAS is fused in-frame with the C-terminus of ER-alpha. [provided by RefSeq, Jul 2008]
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 UniProt Comments for FASN    FASN: a multifunctional enzyme. Catalyzes the synthesis of palmitate from acetyl-CoA and malonyl-CoA, in the presence of NADPH, into long-chain saturated fatty acids. In some cancer cell lines, this protein has been found to be fused with estrogen receptor-alpha (ER-alpha), in which the N-terminus of FAS is fused in-frame with the C-terminus of ER-alpha.

Protein type: Lipid Metabolism - fatty acid biosynthesis; Hydrolase; EC 2.3.1.85; EC 1.3.1.39; EC 1.1.1.100; EC 2.3.1.41; Acetyltransferase; EC 4.2.1.59; EC 3.1.2.14; Lyase; EC 2.3.1.38; EC 2.3.1.39; Oxidoreductase

Chromosomal Location of Human Ortholog: 17q25

Cellular Component: Golgi apparatus; glycogen granule; mitochondrion; membrane; cytoplasm; melanosome; plasma membrane; cytosol

Molecular Function: protein homodimerization activity; fatty-acid synthase activity; 3-oxoacyl-[acyl-carrier-protein] synthase activity; myristoyl-[acyl-carrier-protein] hydrolase activity; zinc ion binding; enoyl-[acyl-carrier-protein] reductase (NADPH, A-specific) activity; enoyl-[acyl-carrier-protein] reductase (NADPH, B-specific) activity; drug binding; [acyl-carrier-protein] S-acetyltransferase activity; 3-oxoacyl-[acyl-carrier-protein] reductase activity; protein binding; 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity; oleoyl-[acyl-carrier-protein] hydrolase activity; palmitoyl-[acyl-carrier-protein] hydrolase activity; [acyl-carrier-protein] S-malonyltransferase activity; 3-hydroxypalmitoyl-[acyl-carrier-protein] dehydratase activity

Biological Process: osteoblast differentiation; vitamin metabolic process; acetyl-CoA metabolic process; pantothenate metabolic process; energy reserve metabolic process; positive regulation of cellular metabolic process; triacylglycerol biosynthetic process; cellular lipid metabolic process; fatty acid metabolic process; water-soluble vitamin metabolic process; fatty acid biosynthetic process
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 Research Articles on FASN    1. MicroRNA-142-3p inhibits the protein expression of FASN in osteosarcoma cell linesthrough binding to its 3'-untranslated region
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with FASN elisa kitDiseases associated with FASN elisa kit
 Products by Pathway  Pathway Diagram
 AMPK Signaling Pathway antibodies  AMPK Signaling Pathway Diagram
 AMPK Signaling Pathway antibodies  AMPK Signaling Pathway Diagram
 AMPK Signaling Pathway antibodies  AMPK Signaling Pathway Diagram
 Activation Of Gene Expression By SREBF (SREBP) Pathway antibodies  Activation Of Gene Expression By SREBF (SREBP) Pathway Diagram
 ChREBP Activates Metabolic Gene Expression Pathway antibodies  ChREBP Activates Metabolic Gene Expression Pathway Diagram
 Defective AMN Causes Hereditary Megaloblastic Anemia 1 Pathway antibodies  Defective AMN Causes Hereditary Megaloblastic Anemia 1 Pathway Diagram
 Defective BTD Causes Biotidinase Deficiency Pathway antibodies  Defective BTD Causes Biotidinase Deficiency Pathway Diagram
 Defective CD320 Causes Methylmalonic Aciduria Pathway antibodies  Defective CD320 Causes Methylmalonic Aciduria Pathway Diagram
 Defective CUBN Causes Hereditary Megaloblastic Anemia 1 Pathway antibodies  Defective CUBN Causes Hereditary Megaloblastic Anemia 1 Pathway Diagram
 Defective GIF Causes Intrinsic Factor Deficiency Pathway antibodies  Defective GIF Causes Intrinsic Factor Deficiency Pathway Diagram
 Disease Name  Pubmed Publications
 Fatty Liver Antibodies  >141 publications with FASN and Fatty Liver
 Obesity Antibodies  >107 publications with FASN and Obesity
 Liver Diseases Antibodies  >64 publications with FASN and Liver Diseases
 Breast Neoplasms Antibodies  >52 publications with FASN and Breast Neoplasms
 Insulin Resistance Antibodies  >48 publications with FASN and Insulin Resistance
 Inflammation Antibodies  >40 publications with FASN and Inflammation
 Disease Models, Animal Antibodies  >26 publications with FASN and Disease Models, Animal
 Weight Loss Antibodies  >22 publications with FASN and Weight Loss
 Necrosis Antibodies  >19 publications with FASN and Necrosis
 Hepatitis Antibodies  >18 publications with FASN and Hepatitis
Organs/Tissues associated with FASN elisa kit
 Organ/Tissue Name  Pubmed Publications
 Liver Antibodies  >165 publications with FASN and Liver
 Adipose Tissue Antibodies  >119 publications with FASN and Adipose Tissue
 Blood Antibodies  >104 publications with FASN and Blood
 Muscle Antibodies  >53 publications with FASN and Muscle
 Prostate Antibodies  >49 publications with FASN and Prostate
 Mammary Gland Antibodies  >34 publications with FASN and Mammary Gland
 Lung Antibodies  >23 publications with FASN and Lung
 Brain Antibodies  >18 publications with FASN and Brain
 Kidney Antibodies  >17 publications with FASN and Kidney
 Vascular Antibodies  >16 publications with FASN and Vascular
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