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FAIM3 elisa kit :: Human Fas apoptotic inhibitory molecule 3 ELISA Kit

Scan QR to view Datasheet Catalog #    MBS903912
Typical Testing Data/Standard Curve (for reference only)
Unit / Price
24-Strip-Wells (LIMIT 1)  /  $250 +1 FREE 8GB USB
48-Strip-Wells  /  $495 +1 FREE 8GB USB
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 Product Name   

Fas apoptotic inhibitory molecule 3 (FAIM3), ELISA Kit

★Popular Item★
 Also Known As   

Human Fas apoptotic inhibitory molecule 3, FAIM3 ELISA Kit

 Product Synonym Names    Human Fas apoptotic inhibitory molecule 3 (FAIM3) ELISA kit; FcmR; TOSO; Fc mu receptor; IgM Fc receptor; immunoglobulin mu Fc receptor; regulator of Fas-induced apoptosis; Fas apoptotic inhibitory molecule 3
 Product Gene Name   

FAIM3 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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  Sample Manual Insert    Download PDF Manual View PDF Manual
 Request for Current Manual Insert    Request Current Manual
 MBS903912 Testing Data    Testing Data PDF
 OMIM    606015
 3D Structure    ModBase 3D Structure for O60667
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 Species Reactivity    Human
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 Specificity    This assay has high sensitivity and excellent specificity for detection of Human FAIM3. No significant cross-reactivity or interference between Human FAIM3 and analogues was observed.
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 Assay Type    Sandwich
 Intra-assay Precision    Intra-assay Precision (Precision within an assay): CV% is less than 8%
Three samples of known concentration were tested twenty times on one plate to assess.
Inter-assay Precision (Precision between assays): CV% is less than 10%
Three samples of known concentration were tested in twenty assays to assess.
 Detection Wavelength    450 nm
 Sample Volume    50-100ul
 Protein Biological Process 1    Immunity
 Protein Biological Process 3    Immunity
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 Preparation and Storage    Unopened test kits should be stored at 2 to 8 degree C upon receipt. Please refer to pdf manual for further storage instructions.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of FAIM3 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for FAIM3 purchase    MBS903912 is a ready-to-use microwell, strip plate Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Fas apoptotic inhibitory molecule 3 (FAIM3) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing FAIM3. The ELISA analytical biochemical technique of the MBS903912 kit is based on FAIM3 antibody-FAIM3 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect FAIM3 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, FAIM3. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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Related Product Information for FAIM3 elisa kit

   Principle of the Assay: This assay employs the quantitative sandwich enzyme immunoassay technique. Antibody specific for FAIM3 has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and any FAIM3 present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for FAIM3 is added to the wells. After washing, avidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of FAIM3 bound in the initial step. The color development is stopped and the intensity of the color is measured.
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 Typical Testing Data/Standard Curve (for reference only) of FAIM3 elisa kit    FAIM3 elisa kit Typical Testing Data/Standard Curve (for reference only) image
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Sample Manual Insert of MBS903912. Click to request current manual
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NCBI/Uniprot data below describe general gene information for FAIM3. It may not necessarily be applicable to this product.
 NCBI GI #    216547554
 NCBI GeneID    9214
 NCBI Accession #    NP_001135945.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001142473.1 [Other Products]
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 UniProt Primary Accession #    O60667 [Other Products]
 UniProt Secondary Accession #    A8K7J2; B7Z6Z0; D9MWM3 [Other Products]
 UniProt Related Accession #    O60667 [Other Products]
 Molecular Weight    43,146 Da
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 NCBI Official Full Name    fas apoptotic inhibitory molecule 3 isoform b
 NCBI Official Synonym Full Names    Fas apoptotic inhibitory molecule 3
 NCBI Official Symbol    FAIM3 [Similar Products]
 NCBI Official Synonym Symbols   
[Similar Products]
 NCBI Protein Information    fas apoptotic inhibitory molecule 3; Fc mu receptor; IgM Fc receptor; immunoglobulin mu Fc receptor; regulator of Fas-induced apoptosis Toso
 UniProt Protein Name    Fas apoptotic inhibitory molecule 3
 UniProt Synonym Protein Names   
Regulator of Fas-induced apoptosis Toso
 Protein Family    Fas apoptotic inhibitory molecule
 UniProt Gene Name    FAIM3 [Similar Products]
 UniProt Synonym Gene Names    TOSO [Similar Products]
 UniProt Entry Name    FAIM3_HUMAN
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 NCBI Summary for FAIM3    Fc receptors specifically bind to the Fc region of immunoglobulins (Igs) to mediate the unique functions of each Ig class. FAIM3 encodes an Fc receptor for IgM (see MIM 147020) (Kubagawa et al., 2009 [PubMed 19858324]; Shima et al., 2010 [PubMed 20042454]).[supplied by OMIM, Jul 2010]
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 UniProt Comments for FAIM3    FAIM3: May play a role in the immune system processes. Protects cells from FAS-, TNF alpha- and FADD-induced apoptosis without increasing expression of the inhibitors of apoptosis BCL2 and BCLXL. Seems to activate an inhibitory pathway that prevents CASP8 activation following FAS stimulation, rather than blocking apoptotic signals downstream. May inhibit FAS-induced apoptosis by preventing CASP8 processing through CFLAR up-regulation. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Apoptosis; Membrane protein, integral

Chromosomal Location of Human Ortholog: 1q32.1

Cellular Component: integral to membrane; extracellular region

Biological Process: immune system process; cellular defense response; negative regulation of apoptosis
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 Research Articles on FAIM3    1. Overexpression of TOSO gene is associated with chronic lymphocytic leukemia.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Diseases associated with FAIM3 elisa kitOrgans/Tissues associated with FAIM3 elisa kit
 Disease Name  Pubmed Publications
 Necrosis Antibodies  >1 publications with FAIM3 and Necrosis
 Neoplasms Antibodies  >1 publications with FAIM3 and Neoplasms
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >3 publications with FAIM3 and Blood
 Placenta Antibodies  >1 publications with FAIM3 and Placenta
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