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FAS elisa kit :: Human Fatty Acid Synthase ELISA Kit

Scan QR to view Datasheet Catalog #    MBS017927 FAS elisa kit
Unit / Price
48-Strip-Wells  /  $435 +1 FREE 8GB USB
96-Strip-Wells  /  $600 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Fatty Acid Synthase (FAS), ELISA Kit

 Also Known As   

Human Fatty Acid Synthase ELISA Kit

 Product Gene Name   

FAS elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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  Manual Insert    Download PDF Manual View PDF Manual
 Chromosome Location    Chromosome: 17; NC_000017.10 (80036214..80056106, complement). Location: 17q25
 OMIM    600212
 3D Structure    ModBase 3D Structure for P49327
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 Species Reactivity    Human
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 Specificity    No significant cross-reactivity or interference between this analyte and analogues is observed.
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 Assay Type    Quantitative Sandwich
 Detection Range    3.12U/L-100U/L.
 Sensitivity    1.0U/L.
 Intra-assay Precision    Intra-assay CV (%) is less than 15%.
 Inter-assay Precision    Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean 100].
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 Preparation and Storage    Store all reagents at 2-8 degree C
 Other Notes    Small volumes of FAS elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for FAS purchase    MBS017927 is a ready-to-use microwell, strip plate Quantitative Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Fatty Acid Synthase (FAS) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range of 3.12U/L-100U/L in biological research samples containing FAS, with an estimated sensitivity of 1.0U/L. The ELISA analytical biochemical technique of the MBS017927 kit is based on FAS antibody-FAS antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect FAS antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, FAS. Appropriate sample types may include undiluted human body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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Product Description specifically for FAS elisa kit

   Background/Introduction: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of FAS (hereafter termed "analyte") in undiluted original Human body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.
Sample Manual Insert of MBS017927
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NCBI/Uniprot data below describe general gene information for FAS. It may not necessarily be applicable to this product.
 NCBI GI #    41872631
 NCBI GeneID    2194
 NCBI Accession #    NP_004095.4 [Other Products]
 NCBI GenBank Nucleotide #    NM_004104.4 [Other Products]
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 UniProt Primary Accession #    P49327 [Other Products]
 UniProt Secondary Accession #    Q13479; Q16702; Q4LE83; Q6P4U5; Q6SS02; Q969R1; Q96C68; Q96IT0 [Other Products]
 UniProt Related Accession #    P49327 [Other Products]
 Molecular Weight    273,427 Da
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 NCBI Official Full Name    fatty acid synthase
 NCBI Official Synonym Full Names    fatty acid synthase
 NCBI Official Symbol    FASN [Similar Products]
 NCBI Official Synonym Symbols   
FAS; OA-519; SDR27X1
[Similar Products]
 NCBI Protein Information    fatty acid synthase; short chain dehydrogenase/reductase family 27X, member 1
 UniProt Protein Name    Fatty acid synthase
 Protein Family    Fatty acid synthase
 UniProt Gene Name    FASN [Similar Products]
 UniProt Synonym Gene Names    FAS [Similar Products]
 UniProt Entry Name    FAS_HUMAN
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 NCBI Summary for FAS    The enzyme encoded by this gene is a multifunctional protein. Its main function is to catalyze the synthesis of palmitate from acetyl-CoA and malonyl-CoA, in the presence of NADPH, into long-chain saturated fatty acids. In some cancer cell lines, this protein has been found to be fused with estrogen receptor-alpha (ER-alpha), in which the N-terminus of FAS is fused in-frame with the C-terminus of ER-alpha. [provided by RefSeq, Jul 2008]
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 UniProt Comments for FAS    FASN: a multifunctional enzyme. Catalyzes the synthesis of palmitate from acetyl-CoA and malonyl-CoA, in the presence of NADPH, into long-chain saturated fatty acids. In some cancer cell lines, this protein has been found to be fused with estrogen receptor-alpha (ER-alpha), in which the N-terminus of FAS is fused in-frame with the C-terminus of ER-alpha.

Protein type: EC 2.3.1.41; EC 2.3.1.85; EC 2.3.1.39; EC 4.2.1.59; Acetyltransferase; EC 1.3.1.39; EC 1.1.1.100; Hydrolase; EC 3.1.2.14; EC 2.3.1.38; Oxidoreductase; Lyase; Lipid Metabolism - fatty acid biosynthesis

Chromosomal Location of Human Ortholog: 17q25

Cellular Component: Golgi apparatus; mitochondrion; membrane; glycogen granule; cytoplasm; plasma membrane; melanosome; cytosol

Molecular Function: protein homodimerization activity; fatty-acid synthase activity; myristoyl-[acyl-carrier-protein] hydrolase activity; 3-oxoacyl-[acyl-carrier-protein] synthase activity; zinc ion binding; enoyl-[acyl-carrier-protein] reductase (NADPH, A-specific) activity; enoyl-[acyl-carrier-protein] reductase (NADPH, B-specific) activity; [acyl-carrier-protein] S-acetyltransferase activity; drug binding; 3-oxoacyl-[acyl-carrier-protein] reductase activity; protein binding; 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity; oleoyl-[acyl-carrier-protein] hydrolase activity; palmitoyl-[acyl-carrier-protein] hydrolase activity; [acyl-carrier-protein] S-malonyltransferase activity; 3-hydroxypalmitoyl-[acyl-carrier-protein] dehydratase activity

Biological Process: osteoblast differentiation; vitamin metabolic process; acetyl-CoA metabolic process; pantothenate metabolic process; energy reserve metabolic process; positive regulation of cellular metabolic process; triacylglycerol biosynthetic process; cellular lipid metabolic process; fatty acid metabolic process; water-soluble vitamin metabolic process; fatty acid biosynthetic process
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 Research Articles on FAS    1. FAS and HER2 overexpression are common in esophageal carcinomas
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products related to Human Fatty Acid Synthase ELISA Kit
 Catalog #  Product Name  Catalog #  Product Name
 MBS2532043  Mouse FASN (Fatty Acid Synthase) CLIA Kit  MBS2065915  APC-Linked Polyclonal Antibody to Fatty Acid Synthase (FASN)
 MBS081033  Chicken Fatty Acid Synthase ELISA Kit  MBS2008051  Biotin-Linked Antibody to Fatty Acid Synthase (FASN)
 MBS005149  Chicken Fatty Acid Synthase ELISA Kit  MBS2065910  Cy3-Linked Polyclonal Antibody to Fatty Acid Synthase (FASN)
 MBS9375796  Plant S-Acyl Fatty Acid Synthase Thioesterase, Medium Chain (OLAH) ELISA Kit  MBS052592  Donkey Fatty Acid Synthase ELISA Kit
 MBS2065929  FITC-Linked Polyclonal Antibody to Fatty Acid Synthase (FASN)  MBS2027676  Polyclonal Antibody to Fatty Acid Synthase (FASN)
Pathways associated with FAS elisa kitDiseases associated with FAS elisa kit
 Products by Pathway  Pathway Diagram
 AMPK Signaling Pathway antibodies  AMPK Signaling Pathway Diagram
 Activation Of Gene Expression By SREBP (SREBF) Pathway antibodies  Activation Of Gene Expression By SREBP (SREBF) Pathway Diagram
 ChREBP Activates Metabolic Gene Expression Pathway antibodies  ChREBP Activates Metabolic Gene Expression Pathway Diagram
 Fatty Acid Biosynthesis Pathway antibodies  Fatty Acid Biosynthesis Pathway Diagram
 Fatty Acyl-CoA Biosynthesis Pathway antibodies  Fatty Acyl-CoA Biosynthesis Pathway Diagram
 Fatty Acid Biosynthesis Pathway antibodies  Fatty Acid Biosynthesis Pathway Diagram
 Fatty Acid Biosynthesis Pathway antibodies  Fatty Acid Biosynthesis Pathway Diagram
 Fatty Acid Biosynthesis, Elongation Pathway antibodies  Fatty Acid Biosynthesis, Elongation Pathway Diagram
 Fatty Acid Biosynthesis, Elongation Pathway antibodies  Fatty Acid Biosynthesis, Elongation Pathway Diagram
 Fatty Acid, Triacylglycerol, And Ketone Body Metabolism Pathway antibodies  Fatty Acid, Triacylglycerol, And Ketone Body Metabolism Pathway Diagram
 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >158 publications with FAS and Neoplasms
 Fatty Liver Antibodies  >81 publications with FAS and Fatty Liver
 Obesity Antibodies  >69 publications with FAS and Obesity
 Liver Diseases Antibodies  >36 publications with FAS and Liver Diseases
 Breast Neoplasms Antibodies  >36 publications with FAS and Breast Neoplasms
 Insulin Resistance Antibodies  >31 publications with FAS and Insulin Resistance
 Inflammation Antibodies  >25 publications with FAS and Inflammation
 Weight Loss Antibodies  >16 publications with FAS and Weight Loss
 Drug Toxicity Antibodies  >15 publications with FAS and Drug Toxicity
 Hepatitis Antibodies  >12 publications with FAS and Hepatitis
Organs/Tissues associated with FAS elisa kit
 Organ/Tissue Name  Pubmed Publications
 Liver Antibodies  >98 publications with FAS and Liver
 Adipose Tissue Antibodies  >73 publications with FAS and Adipose Tissue
 Blood Antibodies  >72 publications with FAS and Blood
 Connective Tissue Antibodies  >45 publications with FAS and Connective Tissue
 Muscle Antibodies  >34 publications with FAS and Muscle
 Prostate Antibodies  >34 publications with FAS and Prostate
 Mammary Gland Antibodies  >21 publications with FAS and Mammary Gland
 Lung Antibodies  >13 publications with FAS and Lung
 Brain Antibodies  >12 publications with FAS and Brain
 Kidney Antibodies  >10 publications with FAS and Kidney
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