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FcgR3A elisa kit :: Human Fc Fragment Of IgG Low Affinity IIIa Receptor (FcgR3A) ELISA Kit

Scan QR to view Datasheet Catalog #    MBS2024221 (SPECIAL PROMOTION: Get FREE Starbucks gift card ($5 for 48-Wells-Kit or $10 for 96-Wells-Kit. Maximum 5 gift cards/product). Gift card(s) will be included with shipment)
Typical Testing Data/Standard Curve (for reference only)
Unit / Price
24-Strip-Wells  /  $260 +1 FREE 8GB USB
48-Strip-Wells  /  $475 +1 FREE 8GB USB
96-Strip-Wells  /  $640 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,590 +3 FREE 8GB USB
10x96-Strip-Wells  /  $4,670 +5 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Fc Fragment Of IgG Low Affinity IIIa Receptor (FcgR3A), ELISA Kit

 Also Known As   

Fc Fragment Of IgG Low Affinity IIIa Receptor (FcgR3A) ELISA Kit

 Product Synonym Names    CD16a; CD16-A; FCGR3-A; FCG3; FcgRIII; IGFR3; NA; Neutrophil Antigen; Low affinity immunoglobulin gamma Fc region receptor III-A
 Product Gene Name   

FcgR3A elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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  Sample Manual Insert    Download PDF Manual View PDF Manual
 Request for Current Manual Insert    Request Current Manual
 OMIM    146740
 3D Structure    ModBase 3D Structure for P08637
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 Species Reactivity    Human
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 Specificity    This assay has high sensitivity and excellent specificity for detection of Fc Fragment Of IgG Low Affinity IIIa Receptor (FcgR3A).
No significant cross-reactivity or interference between Fc Fragment Of IgG Low Affinity IIIa Receptor (FcgR3A) and analogues was observed.
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 Assay Type    Double-antibody Sandwich
 Samples    Serum, Plasma, Tissue homogenates, Cell lysates and Other Biological Fluids
 Detection Range    125-2000ng/mL
 Sensitivity    < 50pg/mL
 Application    Enzyme-linked immunosorbent assay for Antigen Detection.
 Intra-assay Precision (Precision within an assay)    3 samples with low, middle and high level Fc Fragment Of IgG Low Affinity IIIa Receptor (FcgR3A) were tested 20 times on one plate, respectively.
 Inter-assay Precision (Precision between assays)    3 samples with low, middle and high level Fc Fragment Of IgG Low Affinity IIIa Receptor (FcgR3A) were tested on 3 different plates, 8 replicates in each plate.
 CV(%) =    SD/meanX100
 Intra-Assay    CV<10%
 Inter-Assay    CV<12%
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 Preparation and Storage    The stability of kit is determined by the loss rate of activity. The loss rate of this kit is less than 5% within the expiration date under appropriate storage condition.
To minimize extra influence on the performance, operation procedures and lab conditions, especially room temperature, air humidity, incubator temperature should be strictly controlled. It is also strongly suggested that the whole assay is performed by the same operator from the beginning to the end.
 ISO Certification    Manufactured in an ISO 9001:2015 and ISO 13485:2016 Certified Laboratory.
 Supply Chain Verification    Manufactured in a lab with traceable raw materials manufactured on site. Coordinated product portfolio of antibodies, pairs, conjugates, recombinant proteins, and immunoassay materials available. Please inquire.
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of FcgR3A elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for FcgR3A purchase    MBS2024221 is a ready-to-use microwell, strip plate Double-antibody Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Fc Fragment Of IgG Low Affinity IIIa Receptor (FcgR3A) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range of 125-2000ng/mL in biological research samples containing FcgR3A, with an estimated sensitivity of < 50pg/mL. The ELISA analytical biochemical technique of the MBS2024221 kit is based on FcgR3A antibody-FcgR3A antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect FcgR3A antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, FcgR3A. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions such as Serum, Plasma, Tissue homogenates, Cell lysates and Other Biological Fluids. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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Related Product Information for FcgR3A elisa kit

   The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Fc Fragment Of IgG Low Affinity IIIa Receptor (FcgR3A). Standards or samples are then added to the appropriate microtiter plate wells with a biotin-conjugated antibody specific to Fc Fragment Of IgG Low Affinity IIIa Receptor (FcgR3A). Next, Avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. After TMB substrate solution is added, only those wells that contain Fc Fragment Of IgG Low Affinity IIIa Receptor (FcgR3A), biotin-conjugated antibody and enzyme-conjugated Avidin will exhibit a change in color. The enzyme-substrate reaction is terminated by the addition of sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450nm ± 10nm. The concentration of Fc Fragment Of IgG Low Affinity IIIa Receptor (FcgR3A) in the samples is then determined by comparing the O.D. of the samples to the standard curve.
 Product Categories/Family for FcgR3A elisa kit    CD & Adhesion molecule
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 Typical Testing Data/Standard Curve (for reference only) of FcgR3A elisa kit    FcgR3A elisa kit Typical Testing Data/Standard Curve (for reference only) image
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Sample Manual Insert of MBS2024221. Click to request current manual
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NCBI/Uniprot data below describe general gene information for FcgR3A. It may not necessarily be applicable to this product.
 NCBI GI #    22477184
 NCBI GeneID    2214
 NCBI Accession #    AAH36723.1 [Other Products]
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 UniProt Primary Accession #    P08637 [Other Products]
 UniProt Secondary Accession #    Q53FJ0; Q53FL6; Q5EBR4; Q65ZM6; Q6PIJ0; A2N6W9 [Other Products]
 UniProt Related Accession #    P08637 [Other Products]
 Molecular Weight    29,089 Da
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 NCBI Official Full Name    Fc fragment of IgG, low affinity IIIa, receptor (CD16a)
 NCBI Official Synonym Full Names    Fc fragment of IgG, low affinity IIIa, receptor (CD16a)
 NCBI Official Symbol    FCGR3A [Similar Products]
 NCBI Official Synonym Symbols   
CD16; FCG3; CD16A; FCGR3; IGFR3; IMD20; FCR-10; FCRIII; FCGRIII; FCRIIIA
[Similar Products]
 NCBI Protein Information    low affinity immunoglobulin gamma Fc region receptor III-A
 UniProt Protein Name    Low affinity immunoglobulin gamma Fc region receptor III-A
 UniProt Synonym Protein Names   
CD16a antigen; Fc-gamma RIII-alpha; Fc-gamma RIII; Fc-gamma RIIIa; FcRIII; FcRIIIa; FcR-10; IgG Fc receptor III-2; CD_antigen: CD16a
 Protein Family    Low affinity immunoglobulin gamma Fc region receptor
 UniProt Gene Name    FCGR3A [Similar Products]
 UniProt Synonym Gene Names    CD16A; FCG3; FCGR3; IGFR3; Fc-gamma RIII; Fc-gamma RIIIa; FcRIII; FcRIIIa [Similar Products]
 UniProt Entry Name    FCG3A_HUMAN
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 NCBI Summary for FcgR3A    This gene encodes a receptor for the Fc portion of immunoglobulin G, and it is involved in the removal of antigen-antibody complexes from the circulation, as well as other other antibody-dependent responses. This gene (FCGR3A) is highly similar to another nearby gene (FCGR3B) located on chromosome 1. The receptor encoded by this gene is expressed on natural killer (NK) cells as an integral membrane glycoprotein anchored through a transmembrane peptide, whereas FCGR3B is expressed on polymorphonuclear neutrophils (PMN) where the receptor is anchored through a phosphatidylinositol (PI) linkage. Mutations in this gene have been linked to susceptibility to recurrent viral infections, susceptibility to systemic lupus erythematosus, and alloimmune neonatal neutropenia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
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 UniProt Comments for FcgR3A    FCGR3A: Receptor for the Fc region of IgG. Binds complexed or aggregated IgG and also monomeric IgG. Mediates antibody-dependent cellular cytotoxicity (ADCC) and other antibody-dependent responses, such as phagocytosis.

Protein type: Membrane protein, integral

Chromosomal Location of Human Ortholog: 1q23

Cellular Component: plasma membrane; integral to membrane; external side of plasma membrane

Molecular Function: IgG binding

Biological Process: regulation of immune response; innate immune response; immune response

Disease: Immunodeficiency 20
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 Research Articles on FcgR3A    1. No differences in polymorphisms were found between the FCGR polymorphisms HH and the others and VV versus the others in KRAS-WT mCRC patients refractory to irinotecan, oxaliplatin and 5-fluorouracil treated with cetuximab.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with FcgR3A elisa kitPathways associated with FcgR3A elisa kit
 Reference Product  PubMed Publications
 SYK elisa kit  >2 publications with FcgR3A and SYK
 TYROBP elisa kit  >1 publications with FcgR3A and TYROBP
 Products by Pathway  Pathway Diagram
 Adaptive Immune System Pathway antibodies  Adaptive Immune System Pathway Diagram
 FCGR Activation Pathway antibodies  FCGR Activation Pathway Diagram
 Fc Gamma R-mediated Phagocytosis Pathway antibodies  Fc Gamma R-mediated Phagocytosis Pathway Diagram
 Fc Gamma R-mediated Phagocytosis Pathway antibodies  Fc Gamma R-mediated Phagocytosis Pathway Diagram
 Fcgamma Receptor (FCGR) Dependent Phagocytosis Pathway antibodies  Fcgamma Receptor (FCGR) Dependent Phagocytosis Pathway Diagram
 Immune System Pathway antibodies  Immune System Pathway Diagram
 Immunoregulatory Interactions Between A Lymphoid And A Non-Lymphoid Cell Pathway antibodies  Immunoregulatory Interactions Between A Lymphoid And A Non-Lymphoid Cell Pathway Diagram
 Innate Immune System Pathway antibodies  Innate Immune System Pathway Diagram
 Leishmaniasis Pathway antibodies  Leishmaniasis Pathway Diagram
 Leishmaniasis Pathway antibodies  Leishmaniasis Pathway Diagram
Diseases associated with FcgR3A elisa kitOrgans/Tissues associated with FcgR3A elisa kit
 Disease Name  Pubmed Publications
 Necrosis Antibodies  >28 publications with FcgR3A and Necrosis
 Intestinal Diseases Antibodies  >27 publications with FcgR3A and Intestinal Diseases
 Lupus Erythematosus, Systemic Antibodies  >25 publications with FcgR3A and Lupus Erythematosus, Systemic
 Cardiovascular Diseases Antibodies  >23 publications with FcgR3A and Cardiovascular Diseases
 Inflammation Antibodies  >17 publications with FcgR3A and Inflammation
 Leukemia Antibodies  >14 publications with FcgR3A and Leukemia
 Breast Neoplasms Antibodies  >13 publications with FcgR3A and Breast Neoplasms
 Kidney Diseases Antibodies  >12 publications with FcgR3A and Kidney Diseases
 Neoplasms, Experimental Antibodies  >10 publications with FcgR3A and Neoplasms, Experimental
 Carcinoma Antibodies  >8 publications with FcgR3A and Carcinoma
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >156 publications with FcgR3A and Blood
 Kidney Antibodies  >8 publications with FcgR3A and Kidney
 Ovary Antibodies  >6 publications with FcgR3A and Ovary
 Lung Antibodies  >5 publications with FcgR3A and Lung
 Liver Antibodies  >4 publications with FcgR3A and Liver
 Brain Antibodies  >3 publications with FcgR3A and Brain
 Prostate Antibodies  >1 publications with FcgR3A and Prostate
 Intestine Antibodies  >1 publications with FcgR3A and Intestine
 Spleen Antibodies  >1 publications with FcgR3A and Spleen
 Connective Tissue Antibodies  >1 publications with FcgR3A and Connective Tissue
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