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FCGRT elisa kit :: Human Fc fragment of IgG, receptor, transporter, alpha ELISA Kit

Scan QR to view Datasheet Catalog #    MBS937383
Typical Testing Data/Standard Curve (for reference only)
Unit / Price
24-Strip-Wells (LIMIT 1)  /  $250 +1 FREE 8GB USB
48-Strip-Wells  /  $495 +1 FREE 8GB USB
96-Strip-Wells  /  $710 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,705 +3 FREE 8GB USB
10x96-Strip-Wells  /  $5,145 +6 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Fc fragment of IgG, receptor, transporter, alpha (FCGRT), ELISA Kit

 Also Known As   

Human IgG receptor FcRn large subunit p51, FCGRT ELISA Kit

 Product Synonym Names    Human IgG receptor FcRn large subunit p51 (FCGRT) ELISA kit; FCRN; alpha-chain; FcRn alpha chain; IgG receptor FcRn large subunit p51; immunoglobulin receptor; intestinal; heavy chain; major histocompatibility complex class I-like Fc receptor; neonatal Fc-recepto; Fc fragment of IgG; receptor; transporter; alpha
 Product Gene Name   

FCGRT elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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  Sample Manual Insert    Download PDF Manual View PDF Manual
 Request for Current Manual Insert    Request Current Manual
 MBS937383 Testing Data    Testing Data PDF
 OMIM    601437
 3D Structure    ModBase 3D Structure for P55899
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 Species Reactivity    Human
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 Specificity    This assay has high sensitivity and excellent specificity for detection of Human FCGRT. No significant cross-reactivity or interference between Human FCGRT and analogues was observed.
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 Samples    Serum, plasma, tissue homogenates
 Assay Type    Sandwich
 Detection Range    15.6 pg/ml-1000 pg/ml
 Sensitivity    3.9 pg/ml
 Intra-assay Precision    Intra-assay Precision (Precision within an assay): CV% is less than 8%
Three samples of known concentration were tested twenty times on one plate to assess.
Inter-assay Precision (Precision between assays): CV% is less than 10%
Three samples of known concentration were tested in twenty assays to assess.
 Detection Wavelength    450 nm
 Sample Volume    50-100ul
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 Preparation and Storage    Unopened test kits should be stored at 2 to 8 degree C upon receipt. Please refer to pdf manual for further storage instructions.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of FCGRT elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for FCGRT purchase    MBS937383 is a ready-to-use microwell, strip plate Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Fc fragment of IgG, receptor, transporter, alpha (FCGRT) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range of 15.6 pg/ml-1000 pg/ml in biological research samples containing FCGRT, with an estimated sensitivity of 3.9 pg/ml. The ELISA analytical biochemical technique of the MBS937383 kit is based on FCGRT antibody-FCGRT antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect FCGRT antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, FCGRT. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions such as Serum, plasma, tissue homogenates. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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Related Product Information for FCGRT elisa kit

   Principle of the Assay: This assay employs the quantitative sandwich enzyme immunoassay technique. Antibody specific for FCGRT has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and any FCGRT present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for FCGRT is added to the wells. After washing, avidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of FCGRT bound in the initial step. The color development is stopped and the intensity of the color is measured.
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 Typical Testing Data/Standard Curve (for reference only) of FCGRT elisa kit    FCGRT elisa kit Typical Testing Data/Standard Curve (for reference only) image
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Sample Manual Insert of MBS937383. Click to request current manual
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NCBI/Uniprot data below describe general gene information for FCGRT. It may not necessarily be applicable to this product.
 NCBI GI #    209862839
 NCBI GeneID    2217
 NCBI Accession #    NP_001129491.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001136019.2 [Other Products]
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 UniProt Primary Accession #    P55899 [Other Products]
 UniProt Secondary Accession #    Q5HYM5; Q9HBV7; Q9NZ19 [Other Products]
 UniProt Related Accession #    P55899 [Other Products]
 Molecular Weight    39,743 Da
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 NCBI Official Full Name    IgG receptor FcRn large subunit p51
 NCBI Official Synonym Full Names    Fc fragment of IgG, receptor, transporter, alpha
 NCBI Official Symbol    FCGRT [Similar Products]
 NCBI Official Synonym Symbols   
FCRN; alpha-chain
[Similar Products]
 NCBI Protein Information    IgG receptor FcRn large subunit p51; FcRn alpha chain; neonatal Fc receptor; neonatal Fc-receptor for Ig; IgG Fc fragment receptor transporter alpha chain; immunoglobulin receptor, intestinal, heavy chain; major histocompatibility complex class I-like Fc receptor
 UniProt Protein Name    IgG receptor FcRn large subunit p51
 UniProt Synonym Protein Names   
IgG Fc fragment receptor transporter alpha chain; Neonatal Fc receptor
 Protein Family    IgG receptor
 UniProt Gene Name    FCGRT [Similar Products]
 UniProt Synonym Gene Names    FCRN; FcRn [Similar Products]
 UniProt Entry Name    FCGRN_HUMAN
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 NCBI Summary for FCGRT    This gene encodes a receptor that binds the Fc region of monomeric immunoglobulin G. The encoded protein transfers immunoglobulin G antibodies from mother to fetus across the placenta. This protein also binds immunoglobulin G to protect the antibody from degradation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2009]
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 UniProt Comments for FCGRT    FCGRT: Binds to the Fc region of monomeric immunoglobulins gamma. Mediates the uptake of IgG from milk. Possible role in transfer of immunoglobulin G from mother to fetus. Belongs to the immunoglobulin superfamily.

Protein type: Receptor, misc.; Immunoglobulin superfamily; Membrane protein, integral

Chromosomal Location of Human Ortholog: 19q13.3

Cellular Component: plasma membrane; integral to membrane

Molecular Function: IgG binding; beta-2-microglobulin binding; IgG receptor activity; antigen binding

Biological Process: antigen processing and presentation; immune response; IgG immunoglobulin transcytosis in epithelial cells mediated by FcRn immunoglobulin receptor
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 Research Articles on FCGRT    1. Extending serum half-life of albumin by engineering neonatal Fc receptor (FcRn) binding.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with FCGRT elisa kitDiseases associated with FCGRT elisa kit
 Reference Product  PubMed Publications
 B2M elisa kit  >1 publications with FCGRT and B2M
 Disease Name  Pubmed Publications
 Kidney Diseases Antibodies  >1 publications with FCGRT and Kidney Diseases
 Immune System Diseases Antibodies  >1 publications with FCGRT and Immune System Diseases
Organs/Tissues associated with FCGRT elisa kit
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >4 publications with FCGRT and Blood
 Epididymis Antibodies  >1 publications with FCGRT and Epididymis
 Connective Tissue Antibodies  >1 publications with FCGRT and Connective Tissue
 Eye Antibodies  >1 publications with FCGRT and Eye
 Prostate Antibodies  >1 publications with FCGRT and Prostate
 Adipose Tissue Antibodies  >1 publications with FCGRT and Adipose Tissue
 Testis Antibodies  >1 publications with FCGRT and Testis
 Intestine Antibodies  >1 publications with FCGRT and Intestine
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