NP_001018090.1
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NCBI GenBank Nucleotide #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
14,700 Da
NCBI Official Full Name
follitropin subunit beta
NCBI Official Synonym Full Names
follicle stimulating hormone beta subunit
NCBI Official Synonym Symbols
NCBI Protein Information
follitropin subunit beta
UniProt Protein Name
Follitropin subunit beta
UniProt Synonym Protein Names
Follicle-stimulating hormone beta subunit; FSH-B; FSH-beta; Follitropin beta chain
UniProt Synonym Gene Names
UniProt Entry Name
FSHB_HUMAN
NCBI Summary for FSHB
The pituitary glycoprotein hormone family includes follicle-stimulating hormone, luteinizing hormone, chorionic gonadotropin, and thyroid-stimulating hormone. All of these glycoproteins consist of an identical alpha subunit and a hormone-specific beta subunit. This gene encodes the beta subunit of follicle-stimulating hormone. In conjunction with luteinizing hormone, follicle-stimulating hormone induces egg and sperm production. Alternative splicing results in two transcript variants encoding the same protein. [provided by RefSeq, Jul 2008]
UniProt Comments for FSHB
FSHB: Stimulates development of follicle and spermatogenesis in the reproductive organs. Defects in FSHB are a cause of isolated follicle- stimulating hormone deficiency (IFSHD). Selective follicle-stimulating hormone deficiency is an uncommon cause of infertility, producing amenorrhea and hypogonadism in women and oligo or azoospermia with normal testosterone levels in normally virilised men. Belongs to the glycoprotein hormones subunit beta family.
Protein type: Secreted; Secreted, signal peptide
Chromosomal Location of Human Ortholog: 11p13
Cellular Component: cytoplasm; extracellular region
Molecular Function: follicle-stimulating hormone activity; hormone activity; protein binding
Biological Process: cellular protein metabolic process; female gamete generation; female pregnancy; follicle-stimulating hormone signaling pathway; peptide hormone processing; positive regulation of bone resorption; positive regulation of cell migration; positive regulation of cell proliferation; positive regulation of transcription from RNA polymerase II promoter; progesterone biosynthetic process; regulation of osteoclast differentiation; Sertoli cell proliferation; signal transduction; transforming growth factor beta receptor signaling pathway
Disease: Follicle-stimulating Hormone Deficiency, Isolated
Research Articles on FSHB
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Products associated with FSHB elisa kit
Pathways associated with FSHB elisa kit
Diseases associated with FSHB elisa kit
Organs/Tissues associated with FSHB elisa kit
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