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FPR1 elisa kit :: Human Formyl Peptide Receptor 1 (FPR1) ELISA Kit

Scan QR to view Datasheet Catalog #    MBS2000187 (SPECIAL PROMOTION: Get FREE Starbucks gift card ($5 for 48-Wells-Kit or $10 for 96-Wells-Kit. Maximum 5 gift cards/product). Gift card(s) will be included with shipment)
Typical Testing Data/Standard Curve (for reference only)
Unit / Price
24-Strip-Wells  /  $260 +1 FREE 8GB USB
48-Strip-Wells  /  $475 +1 FREE 8GB USB
96-Strip-Wells  /  $640 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,590 +3 FREE 8GB USB
10x96-Strip-Wells  /  $4,670 +5 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Formyl Peptide Receptor 1 (FPR1), ELISA Kit

★Popular Item★
 Also Known As   

Formyl Peptide Receptor 1 (FPR1) ELISA Kit

 Product Synonym Names    FMLP; FPR; fMet-Leu-Phe receptor; N-formylpeptide chemoattractant receptor
 Product Gene Name   

FPR1 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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  Sample Manual Insert    Download PDF Manual View PDF Manual
 Request for Current Manual Insert    Request Current Manual
 OMIM    136537
 3D Structure    ModBase 3D Structure for P21462
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 Species Reactivity    Human
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 Specificity    This assay has high sensitivity and excellent specificity for detection of Formyl Peptide Receptor 1 (FPR1).
No significant cross-reactivity or interference between Formyl Peptide Receptor 1 (FPR1) and analogues was observed.
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 Assay Type    Double-antibody Sandwich
 Samples    Cell lysates, Cell culture supernates and Other Biological Fluids
 Detection Range    0.156-10ng/mL
 Sensitivity    < 0.061ng/mL
 Application    Enzyme-linked immunosorbent assay for Antigen Detection.
 Intra-assay Precision (Precision within an assay)    3 samples with low, middle and high level Formyl Peptide Receptor 1 (FPR1) were tested 20 times on one plate, respectively.
 Inter-assay Precision (Precision between assays)    3 samples with low, middle and high level Formyl Peptide Receptor 1 (FPR1) were tested on 3 different plates, 8 replicates in each plate.
 CV(%) =    SD/meanX100
 Intra-Assay    CV<10%
 Inter-Assay    CV<12%
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 Preparation and Storage    The stability of kit is determined by the loss rate of activity. The loss rate of this kit is less than 5% within the expiration date under appropriate storage condition.
To minimize extra influence on the performance, operation procedures and lab conditions, especially room temperature, air humidity, incubator temperature should be strictly controlled. It is also strongly suggested that the whole assay is performed by the same operator from the beginning to the end.
 ISO Certification    Manufactured in an ISO 9001:2015 and ISO 13485:2016 Certified Laboratory.
 Supply Chain Verification    Manufactured in a lab with traceable raw materials manufactured on site. Coordinated product portfolio of antibodies, pairs, conjugates, recombinant proteins, and immunoassay materials available. Please inquire.
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of FPR1 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for FPR1 purchase    MBS2000187 is a ready-to-use microwell, strip plate Double-antibody Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Formyl Peptide Receptor 1 (FPR1) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range of 0.156-10ng/mL in biological research samples containing FPR1, with an estimated sensitivity of < 0.061ng/mL. The ELISA analytical biochemical technique of the MBS2000187 kit is based on FPR1 antibody-FPR1 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect FPR1 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, FPR1. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions such as Cell lysates, Cell culture supernates and Other Biological Fluids. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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Related Product Information for FPR1 elisa kit

   The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Formyl Peptide Receptor 1 (FPR1). Standards or samples are then added to the appropriate microtiter plate wells with a biotin-conjugated antibody specific to Formyl Peptide Receptor 1 (FPR1). Next, Avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. After TMB substrate solution is added, only those wells that contain Formyl Peptide Receptor 1 (FPR1), biotin-conjugated antibody and enzyme-conjugated Avidin will exhibit a change in color. The enzyme-substrate reaction is terminated by the addition of sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450nm ± 10nm. The concentration of Formyl Peptide Receptor 1 (FPR1) in the samples is then determined by comparing the O.D. of the samples to the standard curve.
 Product Categories/Family for FPR1 elisa kit    Endocrinology
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 Typical Testing Data/Standard Curve (for reference only) of FPR1 elisa kit    FPR1 elisa kit Typical Testing Data/Standard Curve (for reference only) image
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Sample Manual Insert of MBS2000187. Click to request current manual
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NCBI/Uniprot data below describe general gene information for FPR1. It may not necessarily be applicable to this product.
 NCBI GI #    9454516
 NCBI GeneID    2357
 NCBI Accession #    AAF87842.1 [Other Products]
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 UniProt Primary Accession #    P21462 [Other Products]
 UniProt Secondary Accession #    Q14939; Q7Z6A4; Q86U52; Q9NS48 [Other Products]
 UniProt Related Accession #    P21462 [Other Products]
 Molecular Weight    38,446 Da
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 NCBI Official Full Name    formyl peptide receptor 1; FPR1
 NCBI Official Synonym Full Names    formyl peptide receptor 1
 NCBI Official Symbol    FPR1 [Similar Products]
 NCBI Official Synonym Symbols   
FPR; FMLP
[Similar Products]
 NCBI Protein Information    fMet-Leu-Phe receptor
 UniProt Protein Name    fMet-Leu-Phe receptor
 UniProt Synonym Protein Names   
N-formyl peptide receptor; FPR; N-formylpeptide chemoattractant receptor
 Protein Family    FK506-binding protein
 UniProt Gene Name    FPR1 [Similar Products]
 UniProt Synonym Gene Names    fMLP receptor; FPR [Similar Products]
 UniProt Entry Name    FPR1_HUMAN
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 NCBI Summary for FPR1    This gene encodes a G protein-coupled receptor of mammalian phagocytic cells that is a member of the G-protein coupled receptor 1 family. The protein mediates the response of phagocytic cells to invasion of the host by microorganisms and is important in host defense and inflammation.[provided by RefSeq, Jul 2010]
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 UniProt Comments for FPR1    FPR1: High affinity receptor for N-formyl-methionyl peptides, which are powerful neutrophils chemotactic factors. Binding of FMLP to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. Belongs to the G-protein coupled receptor 1 family.

Protein type: Membrane protein, multi-pass; GPCR, family 1; Receptor, GPCR; Membrane protein, integral; Motility/polarity/chemotaxis

Chromosomal Location of Human Ortholog: 19q13.4

Cellular Component: integral to membrane; plasma membrane; endosome

Molecular Function: RAGE receptor binding; protein binding; N-formyl peptide receptor activity; receptor activity

Biological Process: G-protein signaling, coupled to cAMP nucleotide second messenger; G-protein coupled receptor protein signaling pathway; activation of MAPK activity; G-protein signaling, coupled to IP3 second messenger (phospholipase C activating); signal transduction; chemotaxis; cell motility; nitric oxide mediated signal transduction
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 Research Articles on FPR1    1. FPR1 rs78488639 interacted with CFH rs800292, HTRA1 rs11200638, and smoking, enhancing risk to exudative age-related macular degeneration and polypoidal choroidal vasculopathy .
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with FPR1 elisa kitPathways associated with FPR1 elisa kit
 Reference Product  PubMed Publications
 FPR2 elisa kit  >76 publications with FPR1 and FPR2
 ANXA1 elisa kit  >14 publications with FPR1 and ANXA1
 CXCR2 elisa kit  >5 publications with FPR1 and CXCR2
 CCR1 elisa kit  >3 publications with FPR1 and CCR1
 C3AR1 elisa kit  >1 publications with FPR1 and C3AR1
 C5AR1 elisa kit  >1 publications with FPR1 and C5AR1
 Products by Pathway  Pathway Diagram
 Class A/1 (Rhodopsin-like Receptors) Pathway antibodies  Class A/1 (Rhodopsin-like Receptors) Pathway Diagram
 Defective ACTH Causes Obesity And Pro-opiomelanocortinin Deficiency (POMCD) Pathway antibodies  Defective ACTH Causes Obesity And Pro-opiomelanocortinin Deficiency (POMCD) Pathway Diagram
 Disease Pathway antibodies  Disease Pathway Diagram
 Formyl Peptide Receptors Bind Formyl Peptides And Many Other Ligands Pathway antibodies  Formyl Peptide Receptors Bind Formyl Peptides And Many Other Ligands Pathway Diagram
 G Alpha (i) Signalling Events Pathway antibodies  G Alpha (i) Signalling Events Pathway Diagram
 GPCR Downstream Signaling Pathway antibodies  GPCR Downstream Signaling Pathway Diagram
 GPCR Ligand Binding Pathway antibodies  GPCR Ligand Binding Pathway Diagram
 GPCRs, Class A Rhodopsin-like Pathway antibodies  GPCRs, Class A Rhodopsin-like Pathway Diagram
 Metabolic Disorders Of Biological Oxidation Enzymes Pathway antibodies  Metabolic Disorders Of Biological Oxidation Enzymes Pathway Diagram
 Neuroactive Ligand-receptor Interaction Pathway antibodies  Neuroactive Ligand-receptor Interaction Pathway Diagram
Diseases associated with FPR1 elisa kitOrgans/Tissues associated with FPR1 elisa kit
 Disease Name  Pubmed Publications
 Inflammation Antibodies  >77 publications with FPR1 and Inflammation
 Disease Models, Animal Antibodies  >9 publications with FPR1 and Disease Models, Animal
 Cardiovascular Diseases Antibodies  >8 publications with FPR1 and Cardiovascular Diseases
 Necrosis Antibodies  >8 publications with FPR1 and Necrosis
 Lung Diseases Antibodies  >6 publications with FPR1 and Lung Diseases
 Liver Diseases Antibodies  >6 publications with FPR1 and Liver Diseases
 Heart Diseases Antibodies  >4 publications with FPR1 and Heart Diseases
 Pain Antibodies  >3 publications with FPR1 and Pain
 Myocardial Ischemia Antibodies  >3 publications with FPR1 and Myocardial Ischemia
 Asthma Antibodies  >3 publications with FPR1 and Asthma
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >82 publications with FPR1 and Blood
 Lung Antibodies  >12 publications with FPR1 and Lung
 Brain Antibodies  >9 publications with FPR1 and Brain
 Bone Marrow Antibodies  >9 publications with FPR1 and Bone Marrow
 Intestine Antibodies  >7 publications with FPR1 and Intestine
 Kidney Antibodies  >6 publications with FPR1 and Kidney
 Heart Antibodies  >6 publications with FPR1 and Heart
 Eye Antibodies  >5 publications with FPR1 and Eye
 Stomach Antibodies  >3 publications with FPR1 and Stomach
 Spleen Antibodies  >2 publications with FPR1 and Spleen
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