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FZD3 elisa kit :: Human Frizzled Homolog 3 (FZD3) ELISA Kit

Scan QR to view Datasheet Catalog #    MBS9300151 FZD3 elisa kit
Unit / Price
48-Strip-Wells  /  $435 +1 FREE 8GB USB
96-Strip-Wells  /  $600 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,650 +3 FREE 8GB USB
10x96-Strip-Wells  /  $5,205 +6 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Frizzled Homolog 3 (FZD3), ELISA Kit

 Also Known As   

Human Frizzled Homolog 3 (FZD3) ELISA Kit

 Product Gene Name   

FZD3 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Request for Manual Insert    Request Manual
 Chromosome Location    Chromosome: 8; NC_000008.10 (28351722..28431785). Location: 8p21
 OMIM    606143
 3D Structure    ModBase 3D Structure for Q9NPG1
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 Species Reactivity    Human
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 Preparation and Storage    Store all reagents at 2-8 degree C
 Product Note    Our ELISA assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay.
 Other Notes    Small volumes of FZD3 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for FZD3 purchase    MBS9300151 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Frizzled Homolog 3 (FZD3) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing FZD3. The ELISA analytical biochemical technique of the MBS9300151 kit is based on FZD3 antibody-FZD3 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect FZD3 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, FZD3. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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NCBI/Uniprot data below describe general gene information for FZD3. It may not necessarily be applicable to this product.
 NCBI GI #    313851102
 NCBI GeneID    7976
 NCBI Accession #    NP_665873.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_145866.1 [Other Products]
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 UniProt Primary Accession #    Q9NPG1 [Other Products]
 UniProt Related Accession #    Q9NPG1 [Other Products]
 Molecular Weight    76,263 Da
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 NCBI Official Full Name    frizzled-3
 NCBI Official Synonym Full Names    frizzled family receptor 3
 NCBI Official Symbol    FZD3 [Similar Products]
 NCBI Official Synonym Symbols   
Fz-3
[Similar Products]
 NCBI Protein Information    frizzled-3; frizzled homolog 3; frizzled 3, seven transmembrane spanning receptor
 UniProt Protein Name    Frizzled-3
 UniProt Gene Name    FZD3 [Similar Products]
 UniProt Synonym Gene Names    Fz-3; hFz3 [Similar Products]
 UniProt Entry Name    FZD3_HUMAN
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 NCBI Summary for FZD3    This gene is a member of the frizzled gene family. Members of this family encode seven-transmembrane domain proteins that are receptors for the wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. The function of this protein is unknown, although it may play a role in mammalian hair follicle development. Alternative splicing results in multiple transcript variants. This gene is a susceptibility locus for schizophrenia. [provided by RefSeq, Dec 2010]
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 UniProt Comments for FZD3    FZD3: Receptor for Wnt proteins. Most of frizzled receptors are coupled to the beta-catenin canonical signaling pathway, which leads to the activation of disheveled proteins, inhibition of GSK- 3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes. A second signaling pathway involving PKC and calcium fluxes has been seen for some family members, but it is not yet clear if it represents a distinct pathway or if it can be integrated in the canonical pathway, as PKC seems to be required for Wnt-mediated inactivation of GSK-3 kinase. Both pathways seem to involve interactions with G-proteins. May be involved in transduction and intercellular transmission of polarity information during tissue morphogenesis and/or in differentiated tissues. Belongs to the G-protein coupled receptor Fz/Smo family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral; Membrane protein, multi-pass; Receptor, GPCR; GPCR, Fz/Smo family

Chromosomal Location of Human Ortholog: 8p21

Cellular Component: cell surface; cell soma; axon; dendrite; apical plasma membrane; cytoplasm; integral to membrane; presynaptic active zone; plasma membrane; lateral plasma membrane

Molecular Function: G-protein coupled receptor activity; Wnt-protein binding; protein binding; Wnt receptor activity; PDZ domain binding

Biological Process: neuron differentiation; positive regulation of neuroblast proliferation; G-protein coupled receptor protein signaling pathway; inner ear morphogenesis; hair follicle development; neural tube closure; neuron migration; establishment of planar polarity; Wnt receptor signaling pathway through beta-catenin; cell proliferation in midbrain; negative regulation of mitotic cell cycle, embryonic
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 Research Articles on FZD3    1. Genetic variants of the FZD3 gene may affect susceptibility to schizophrenia in Chinese Han and Va populations.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with FZD3 elisa kitPathways associated with FZD3 elisa kit
 Reference Product  PubMed Publications
 WNT5A elisa kit  >14 publications with FZD3 and WNT5A
 LRP5 elisa kit  >8 publications with FZD3 and LRP5
 WNT7A elisa kit  >7 publications with FZD3 and WNT7A
 WNT11 elisa kit  >7 publications with FZD3 and WNT11
 WNT3A elisa kit  >7 publications with FZD3 and WNT3A
 DVL2 elisa kit  >7 publications with FZD3 and DVL2
 WNT2B elisa kit  >5 publications with FZD3 and WNT2B
 LRP6 elisa kit  >5 publications with FZD3 and LRP6
 DVL3 elisa kit  >4 publications with FZD3 and DVL3
 DVL1 elisa kit  >3 publications with FZD3 and DVL1
 Products by Pathway  Pathway Diagram
 Basal Cell Carcinoma Pathway antibodies  Basal Cell Carcinoma Pathway Diagram
 Basal Cell Carcinoma Pathway antibodies  Basal Cell Carcinoma Pathway Diagram
 Class B/2 (Secretin Family Receptors) Pathway antibodies  Class B/2 (Secretin Family Receptors) Pathway Diagram
 GPCR Ligand Binding Pathway antibodies  GPCR Ligand Binding Pathway Diagram
 HTLV-I Infection Pathway antibodies  HTLV-I Infection Pathway Diagram
 HTLV-I Infection Pathway antibodies  HTLV-I Infection Pathway Diagram
 Hippo Signaling Pathway antibodies  Hippo Signaling Pathway Diagram
 Hippo Signaling Pathway antibodies  Hippo Signaling Pathway Diagram
 Melanogenesis Pathway antibodies  Melanogenesis Pathway Diagram
 Melanogenesis Pathway antibodies  Melanogenesis Pathway Diagram
Diseases associated with FZD3 elisa kitOrgans/Tissues associated with FZD3 elisa kit
 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >34 publications with FZD3 and Neoplasms
 Congenital Abnormalities Antibodies  >9 publications with FZD3 and Congenital Abnormalities
 Bipolar Disorder Antibodies  >5 publications with FZD3 and Bipolar Disorder
 Immune System Diseases Antibodies  >5 publications with FZD3 and Immune System Diseases
 Neurobehavioral Manifestations Antibodies  >4 publications with FZD3 and Neurobehavioral Manifestations
 Central Nervous System Diseases Antibodies  >4 publications with FZD3 and Central Nervous System Diseases
 Brain Diseases Antibodies  >3 publications with FZD3 and Brain Diseases
 Nervous System Malformations Antibodies  >3 publications with FZD3 and Nervous System Malformations
 Inflammation Antibodies  >2 publications with FZD3 and Inflammation
 Drug Toxicity Antibodies  >2 publications with FZD3 and Drug Toxicity
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >28 publications with FZD3 and Brain
 Testis Antibodies  >5 publications with FZD3 and Testis
 Kidney Antibodies  >5 publications with FZD3 and Kidney
 Intestine Antibodies  >2 publications with FZD3 and Intestine
 Heart Antibodies  >2 publications with FZD3 and Heart
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