NP_001123478.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
55,756 Da
NCBI Official Full Name
eukaryotic peptide chain release factor GTP-binding subunit ERF3A isoform 2
NCBI Official Synonym Full Names
G1 to S phase transition 1
NCBI Protein Information
eukaryotic peptide chain release factor GTP-binding subunit ERF3A; G1 to S phase transition protein 1 homolog; eukaryotic peptide chain release factor subunit 3a
UniProt Protein Name
Eukaryotic peptide chain release factor GTP-binding subunit ERF3A
UniProt Synonym Protein Names
G1 to S phase transition protein 1 homolog
UniProt Synonym Gene Names
ERF3A; Eukaryotic peptide chain release factor subunit 3a; eRF3a [Similar Products]
UniProt Entry Name
ERF3A_HUMAN
UniProt Comments for GSPT1
GSPT1 iso3: Involved in translation termination in response to the termination codons UAA, UAG and UGA. Stimulates the activity of ERF1. Involved in regulation of mammalian cell growth. Component of the transient SURF complex which recruits UPF1 to stalled ribosomes in the context of nonsense-mediated decay (NMD) of mRNAs containing premature stop codons. Belongs to the GTP-binding elongation factor family. ERF3 subfamily. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Translation; Cell cycle regulation; RNA-binding; Hydrolase
Chromosomal Location of Human Ortholog: 16p13.1
Cellular Component: intracellular
Molecular Function: GTPase activity; protein binding; GTP binding; translation release factor activity
Biological Process: protein amino acid methylation; mRNA catabolic process, nonsense-mediated decay; translational termination; G1/S transition of mitotic cell cycle
Research Articles on GSPT1
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Products associated with GSPT1 elisa kit
Pathways associated with GSPT1 elisa kit
Diseases associated with GSPT1 elisa kit
Organs/Tissues associated with GSPT1 elisa kit
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