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GALR1 elisa kit :: Human GALR1 ELISA Kit

Scan QR to view Datasheet Catalog #    MBS2500552
Typical Testing Data/Standard Curve (for reference only)
Unit / Price
48-Strip-Wells  /  $410 +1 FREE 8GB USB
96-Strip-Wells  /  $490 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,040 +2 FREE 8GB USB
10x96-Strip-Wells  /  $3,590 +4 FREE 8GB USB
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 Product Name   


★Popular Item★
 Also Known As   

Human GALR1 (Galanin Receptor 1) ELISA Kit

 Product Gene Name   

GALR1 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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  Sample Manual Insert    Download PDF Manual View PDF Manual
 Request for Current Manual Insert    Request Current Manual
 OMIM    600377
 3D Structure    ModBase 3D Structure for P47211
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 Species Reactivity    Human
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 Specificity    This kit recognizes natural and recombinant Human GALR1. No significant cross-reactivity or interference between Human GALR1 and analogues was observed.
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 Samples    Serum, Plasma, Biological Fluids
 Assay Type    Sandwich
 Detection Range    0.156-10ng/mL
 Sensitivity    Min: 0.094ng/mL; Max: 10ng/mL
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 Preparation and Storage    Store at 4 degree C.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of GALR1 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for GALR1 purchase    MBS2500552 is a ready-to-use microwell, strip plate Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the GALR1, ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range of 0.156-10ng/mL in biological research samples containing GALR1, with an estimated sensitivity of Min: 0.094ng/mL; Max: 10ng/mL. The ELISA analytical biochemical technique of the MBS2500552 kit is based on GALR1 antibody-GALR1 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect GALR1 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, GALR1. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions such as Serum, Plasma, Biological Fluids. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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Related Product Information for GALR1 elisa kit

   Intended Uses: This ELISA kit applies to the in vitro quantitative determination of Human GALR1 concentrations in serum, plasma and other biological fluids.

Principle of the Assay: This ELISA kit uses Sandwich-ELISA as the method. The micro ELISA plate provided in this kit has been pre-coated with an antibody specific to GALR1. Standards or samples are added to the appropriate micro ELISA plate wells and combined with the specific antibody. Then a biotinylated detection antibody specific for GALR1 and Avidin-Horseradish Peroxidase (HRP) conjugate is added to each micro plate well successively and incubated. Free components are washed away. The substrate solution is added to each well. Only those wells that contain GALR1, biotinylated detection antibody and Avidin-HRP conjugate will appear blue in color. The enzyme-substrate reaction is terminated by the addition of a sulphuric acid solution and the color turns yellow. The optical density (OD) is measured spectrophotometrically at a wavelength of 450 nm +/- 2 nm. The OD value is proportional to the concentration of GALR1. You can calculate the concentration of GALR1 in the samples by comparing the OD of the samples to the standard curve.
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 Typical Testing Data/Standard Curve (for reference only) of GALR1 elisa kit    GALR1 elisa kit Typical Testing Data/Standard Curve (for reference only) image
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Sample Manual Insert of MBS2500552. Click to request current manual
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NCBI/Uniprot data below describe general gene information for GALR1. It may not necessarily be applicable to this product.
 NCBI GI #    167000885
 NCBI GeneID    2587
 NCBI Accession #    NP_001471.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_001480.3 [Other Products]
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 UniProt Primary Accession #    P47211 [Other Products]
 UniProt Secondary Accession #    Q4VBL7 [Other Products]
 UniProt Related Accession #    P47211 [Other Products]
 Molecular Weight    38,953 Da
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 NCBI Official Full Name    galanin receptor type 1
 NCBI Official Synonym Full Names    galanin receptor 1
 NCBI Official Symbol    GALR1 [Similar Products]
 NCBI Official Synonym Symbols   
[Similar Products]
 NCBI Protein Information    galanin receptor type 1; GAL1-R; GALR-1
 UniProt Protein Name    Galanin receptor type 1
 Protein Family    Galanin receptor
 UniProt Gene Name    GALR1 [Similar Products]
 UniProt Synonym Gene Names    GALNR; GALNR1; GAL1-R; GALR-1 [Similar Products]
 UniProt Entry Name    GALR1_HUMAN
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 NCBI Summary for GALR1    The neuropeptide galanin elicits a range of biological effects by interaction with specific G-protein-coupled receptors. Galanin receptors are seven-transmembrane proteins shown to activate a variety of intracellular second-messenger pathways. GALR1 inhibits adenylyl cyclase via a G protein of the Gi/Go family. GALR1 is widely expressed in the brain and spinal cord, as well as in peripheral sites such as the small intestine and heart. [provided by RefSeq, Jul 2008]
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 UniProt Comments for GALR1    GALR1: Receptor for the hormone galanin. The activity of this receptor is mediated by G proteins that inhibit adenylate cyclase activity. Belongs to the G-protein coupled receptor 1 family.

Protein type: Receptor, GPCR; Membrane protein, multi-pass; Membrane protein, integral; GPCR, family 1

Chromosomal Location of Human Ortholog: 18q23

Cellular Component: integral to membrane; plasma membrane

Molecular Function: neuropeptide binding; protein binding; peptide hormone binding; galanin receptor activity

Biological Process: positive regulation of cortisol secretion; elevation of cytosolic calcium ion concentration; neuropeptide signaling pathway; negative regulation of adenylate cyclase activity; digestion; positive regulation of transcription from RNA polymerase II promoter; G-protein signaling, adenylate cyclase activating pathway
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 Research Articles on GALR1    1. Variants in genes for galanin (GAL) and its receptors (GALR1, GALR2, GALR3), despite their disparate genomic loci, conferred increased risk of depression and anxiety in people who experienced childhood adversity or recent negative life events.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with GALR1 elisa kitPathways associated with GALR1 elisa kit
 Reference Product  PubMed Publications
 GALR2 elisa kit  >153 publications with GALR1 and GALR2
 GALR3 elisa kit  >79 publications with GALR1 and GALR3
 GAL elisa kit  >53 publications with GALR1 and GAL
 NPY elisa kit  >4 publications with GALR1 and NPY
 POMC elisa kit  >3 publications with GALR1 and POMC
 NPY1R elisa kit  >1 publications with GALR1 and NPY1R
 Products by Pathway  Pathway Diagram
 Class A/1 (Rhodopsin-like Receptors) Pathway antibodies  Class A/1 (Rhodopsin-like Receptors) Pathway Diagram
 Defective ACTH Causes Obesity And Pro-opiomelanocortinin Deficiency (POMCD) Pathway antibodies  Defective ACTH Causes Obesity And Pro-opiomelanocortinin Deficiency (POMCD) Pathway Diagram
 Disease Pathway antibodies  Disease Pathway Diagram
 G Alpha (i) Signalling Events Pathway antibodies  G Alpha (i) Signalling Events Pathway Diagram
 GPCR Downstream Signaling Pathway antibodies  GPCR Downstream Signaling Pathway Diagram
 GPCR Ligand Binding Pathway antibodies  GPCR Ligand Binding Pathway Diagram
 GPCRs, Class A Rhodopsin-like Pathway antibodies  GPCRs, Class A Rhodopsin-like Pathway Diagram
 Metabolic Disorders Of Biological Oxidation Enzymes Pathway antibodies  Metabolic Disorders Of Biological Oxidation Enzymes Pathway Diagram
 Neuroactive Ligand-receptor Interaction Pathway antibodies  Neuroactive Ligand-receptor Interaction Pathway Diagram
 Neuroactive Ligand-receptor Interaction Pathway antibodies  Neuroactive Ligand-receptor Interaction Pathway Diagram
Diseases associated with GALR1 elisa kitOrgans/Tissues associated with GALR1 elisa kit
 Disease Name  Pubmed Publications
 Seizures Antibodies  >22 publications with GALR1 and Seizures
 Inflammation Antibodies  >9 publications with GALR1 and Inflammation
 Death Antibodies  >6 publications with GALR1 and Death
 Necrosis Antibodies  >4 publications with GALR1 and Necrosis
 Learning Disorders Antibodies  >4 publications with GALR1 and Learning Disorders
 Weight Gain Antibodies  >4 publications with GALR1 and Weight Gain
 Adenoma Antibodies  >3 publications with GALR1 and Adenoma
 Memory Disorders Antibodies  >3 publications with GALR1 and Memory Disorders
 Diabetes Mellitus Antibodies  >2 publications with GALR1 and Diabetes Mellitus
 Cognition Disorders Antibodies  >2 publications with GALR1 and Cognition Disorders
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >114 publications with GALR1 and Brain
 Nerve Antibodies  >35 publications with GALR1 and Nerve
 Prostate Antibodies  >2 publications with GALR1 and Prostate
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